IP Library Granted Patent US 12,156,533
Granted Patent B2
US 12,156,533 · App. 17/171,976 · Granted Dec 3, 2024

Nicotine salt formulations for aerosol devices and methods thereof

Inventors: Adam Bowen (San Francisco, CA); Chenyue Xing (San Francisco, CA)
Assignee: JUUL LABS, INC.
A24B15/167A24B15/16A61K9/007A61K9/12A61K31/465A61K31/60A61K47/10A24F40/10
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Quick Facts
Patent No.
US 12,156,533
App. No.
17/171,976
Granted
Dec 3, 2024
Kind
B2
Abstract

A nicotine salt liquid formulation for generating an inhalable aerosol in an electronic cigarette comprising nicotine salt that forms about 0.5% to about 20% nicotine is provided.

Claims (29)

1. An electronic cigarette comprising a cartridge, wherein the cartridge comprises a nicotine salt liquid formulation, wherein:

(a) the nicotine salt liquid formulation comprises a salt of nicotine and an organic acid in a liquid carrier, wherein the organic acid is benzoic acid or lactic acid;

(b) the salt is present in an amount that forms a nicotine concentration of 0.5% (w/w) to 20% (w/w) in the nicotine salt liquid formulation;

(c) the liquid carrier comprises glycerol and propylene glycol; and

(d) the nicotine salt liquid formulation generates an inhalable aerosol upon heating in the electronic cigarette.

2. The electronic cigarette of claim 1 , wherein the liquid carrier further comprises water.

3. The electronic cigarette of claim 1 , wherein the salt is present in an amount that forms a nicotine concentration of 1% (w/w) to 18% (w/w) in the nicotine salt liquid formulation.

4. The electronic cigarette of claim 1 , wherein the salt is present in an amount that forms a nicotine concentration of 3% (w/w) to 15% (w/w) in the nicotine salt liquid formulation.

5. The electronic cigarette of claim 1 , wherein the salt is present in an amount that forms a nicotine concentration of 4% (w/w) to 12% (w/w) in the nicotine salt liquid formulation.

6. The electronic cigarette of claim 1 , wherein the nicotine salt liquid formulation further comprises a flavorant.

7. The electronic cigarette of claim 1 , wherein the nicotine salt liquid formulation further comprises one or more additional organic acids.

8. The electronic cigarette of claim 1 , wherein the cartridge is configured to serve as a mouthpiece and a reservoir, wherein the reservoir holds the nicotine salt liquid formulation.

9. The electronic cigarette of claim 1 , wherein the organic acid is benzoic acid.

10. The electronic cigarette of claim 1 , wherein the organic acid is lactic acid.

11. A method of providing nicotine to a user, the method comprising:

(a) heating a nicotine salt liquid formulation in an electronic cigarette to produce an inhalable aerosol, and

(b) inhalation of the aerosol by the user;

wherein:

(i) the nicotine salt liquid formulation comprises a salt of nicotine and benzoic acid in a liquid carrier;

(ii) the salt is present in an amount that forms a nicotine concentration of 0.5% (w/w) to 20% (w/w) in the nicotine salt liquid formulation; and

(iii) the liquid carrier comprises glycerol and propylene glycol.

12. The method of claim 11 , wherein the liquid carrier further comprises water.

13. The method of claim 11 , wherein the salt is present in an amount that forms a nicotine concentration of 1% (w/w) to 20% (w/w) in the nicotine salt liquid formulation.

14. The method of claim 11 , wherein the salt is present in an amount that forms a nicotine concentration of 1% (w/w) to 18% (w/w) in the nicotine salt liquid formulation.

15. The method of claim 11 , wherein the salt is present in an amount that forms a nicotine concentration of 3% (w/w) to 15% (w/w) in the nicotine salt liquid formulation.

16. The method of claim 11 , wherein the salt is present in an amount that forms a nicotine concentration of 4% (w/w) to 12% (w/w) in the nicotine salt liquid formulation.

17. The method of claim 11 , wherein the nicotine salt liquid formulation further comprises a flavorant.

18. The method of claim 11 , wherein the nicotine salt liquid formulation further comprises one or more additional organic acids.

19. The method of claim 11 , wherein the electronic cigarette comprises a cartridge, and the cartridge is configured to serve as a mouthpiece and a reservoir, wherein the reservoir holds the nicotine salt liquid formulation.

Assignments (13)
SECURITY INTEREST Recorded Jul 25, 2025
From: JUUL LABS, INC.
To: JLI NATIONAL SETTLEMENT TRUST
Reel/Frame 072224/0075 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 29, 2024
From: BOWEN, ADAM; XING, CHENYUE
To: PLOOM, INC.
Reel/Frame 069063/0653 →
CHANGE OF NAME Recorded Oct 29, 2024
From: PAX LABS, INC.
To: JUUL LABS, INC.
Reel/Frame 069268/0407 →
CHANGE OF NAME Recorded Oct 29, 2024
From: PLOOM, INC.
To: PAX LABS, INC.
Reel/Frame 069268/0409 →
RELEASE OF SECURITY INTEREST Recorded Oct 17, 2024
From: ALTER DOMUS (US) LLC
To: JUUL LABS, INC.; VMR PRODUCTS LLC; ENVENIO INC.
Reel/Frame 069185/0228 →
SECURITY INTEREST Recorded Jul 11, 2023
From: JUUL LABS, INC.; VMR PRODUCTS LLC; ENVENIO INC.
To: ALTER DOMUS (US) LLC
Reel/Frame 064252/0225 →
CORRECTIVE ASSIGNMENT TO CORRECT THE THE ASSIGNEE ADDRESS PREVIOUSLY RECORDED AT REEL: 062114 FRAME: 0196. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 23, 2022
From: JUUL LABS, INC.
To: JLI NATIONAL SETTLEMENT TRUST
Reel/Frame 062214/0142 →
SECURITY INTEREST Recorded Dec 10, 2022
From: JUUL LABS, INC.
To: JLI NATIONAL SETTLEMENT TRUST
Reel/Frame 062114/0195 →
RELEASE OF SECURITY INTEREST Recorded Oct 2, 2022
From: CORTLAND CAPITAL MARKET SERVICES LLC
To: JUUL LABS, INC.
Reel/Frame 061588/0189 →
SECURITY INTEREST Recorded Sep 30, 2022
From: JUUL LABS, INC.
To: ALTER DOMUS (US) LLC
Reel/Frame 061578/0865 →
RELEASE OF SECURITY INTEREST Recorded Jun 28, 2022
From: MUFG UNION BANK, N.A.
To: JUUL LABS, INC.
Reel/Frame 060446/0261 →
SECURITY INTEREST Recorded May 19, 2021
From: JUUL LABS, INC.
To: CORTLAND CAPITAL MARKET SERVICES LLC
Reel/Frame 057681/0094 →
SECURITY INTEREST Recorded May 18, 2021
From: JUUL LABS, INC.
To: MUFG UNION BANK, N.A.
Reel/Frame 056281/0893 →
Continuity (5)
Continuation 14925961 · Oct 28, 2015
Continuation 14271071 · May 6, 2014
Provisional Application 61912507 · Dec 5, 2013
Provisional Application 61820128 · May 6, 2013
Related Publication 20210186082A1 · Jun 24, 2021