IP Library Granted Patent US 11,850,391
Granted Patent B2
US 11,850,391 · App. 17/174,533 · Granted Dec 26, 2023

Aseptic connector

Inventors: Eric Faldt (Uppsala, SE); Klaus Gebauer (Uppsala, SE)
Assignee: CYTIVA SWEDEN AB
A61M39/105A61M39/16A61M39/18F16L39/00F16L2201/44
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Quick Facts
Patent No.
US 11,850,391
App. No.
17/174,533
Granted
Dec 26, 2023
Kind
B2
Abstract

Aseptic connectors are described. An aseptic connector includes a first connection unit and a second connection unit provided with at least one first and second openings orientated to substantially coincide when said first and second connection units are connected to each other. The first and second openings are sealed by at least one film, so that the contact between the film and each connection unit is aseptic. The at least one film is adapted to be mated with a corresponding film on the other connection unit; and the mated films are adapted to be pulled out together two and two after mating such that corresponding first and second openings are mated aseptically.

Claims (18)

1. An aseptic manifold comprising,

a first connection unit having a first side and a second side that is opposite to the first side, wherein the first side of the first connection unit comprises four first ports and the second side of the first connection unit comprises a first terminal end surface, wherein the first terminal end surface is provided with four first openings sealed by a first film and each first opening is in fluid communication with a corresponding first port, and

a second connection unit having a first side and a second side that is opposite to the first side, wherein the first side of the second connection unit comprises four second ports and the second side of the second connection unit comprises a second terminal end surface, wherein the second terminal end surface is provided with four second openings sealed by a second film and each second opening is in fluid communication with a corresponding second port,

wherein each of the first openings is positioned to coincide with a corresponding second opening when the units are connected,

wherein the first openings are arranged in a straight line along the first terminal end surface, and

wherein the second openings are arranged in a straight line along the second terminal end surface,

wherein the first film of the first connection unit is adapted to be mated with the second film of the second connection unit such that when the first and the second connection units are connected to each other the mated films are adapted to be pulled out together to allow the first and second terminal end surfaces to mate aseptically,

wherein two ends of each of the first film and the second film extend laterally beyond corresponding two ends of the first and second connection unit, and

wherein each of the first film and the second film is unfolded.

2. The aseptic manifold of claim 1 , wherein the aseptic manifold is a disposable unit.

3. The aseptic manifold of claim 1 , wherein a gasket is arranged around each opening and a gasket around a first opening is adapted to mate with a corresponding gasket around a second opening when first and the second connection units mate with each other such that each first opening is sealingly connected with its corresponding second opening.

4. The aseptic manifold of claim 3 , wherein a first foam layer is arranged around each gasket of the first terminal surface and a second foam layer is arranged around each gasket of the second terminal surface such that the first foam layer is adapted to be compressed with the second foam layer when two connection units are mated.

5. The aseptic manifold of claim 1 , wherein at least one of the first and second ports is provided with a valve, which is arranged to control fluid flow through the aseptic manifold.

6. The aseptic manifold of claim 1 , further comprising measuring means that comprises a sensor with an optional RFID tag arranged at the aseptic manifold.

7. The aseptic manifold of claim 1 , wherein the first and second connection units are provided with orientation specific locking means arranged to mechanically lock the connection units to each other.

8. The aseptic manifold of claim 1 , wherein the first and second terminal surfaces define a respective rectangular edge.

9. A sterile circuit comprising at least two lengths of tubing each fluidically connected to one of the four ports of the first connection unit of claim 1 .

10. The sterile circuit of claim 9 , further comprising a container fluidically connected to the at least two lengths of tubing.

Assignments (2)
CHANGE OF NAME Recorded Feb 15, 2021
From: GE HEALTHCARE BIO-SCIENCES AB
To: CYTIVA SWEDEN AB
Reel/Frame 055302/0669 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 12, 2021
From: FALDT, ERIC; GEBAUER, KLAUS
To: GE HEALTHCARE BIO-SCIENCES AB
Reel/Frame 055242/0465 →
Priority Claims (1)
SE 1250301-7 · Mar 27, 2012 · national
Continuity (3)
Division 15625401 · Jun 16, 2017
Division 14385307
Related Publication 20210162192A1 · Jun 3, 2021