Oral cannabinoid tablet

1. An oral chewable tablet for delivery of cannabinoids comprising a population of particles and one or more cannabinoids, the population of particles comprising a) directly compressible (DC) particles and b) non-directly compressible (non-DC) sweetener particles, the non-DC sweetener particles providing the tablet with a plurality of discrete non-DC areas, wherein the tablet comprises said non-DC sweetener particles in an amount of at least 10% by weight of the tablet.

2. The oral chewable tablet according to claim 1 , wherein at least 30% by weight of the non-DC sweetener particles have a particle size above 500 μm.

3. The oral chewable tablet according to claim 1 , wherein the one or more cannabinoids are selected from the group consisting of cannabidiol (CBD), cannabidiolic acid (CBDA), cannabidivarin (CBDV), salts and derivatives thereof.

4. The oral tablet according to claim 1 , wherein the one or more cannabinoids are selected from the group consisting of tetrahydrocannabinol (THC), tetrahydrocannabinolic acid (THCA), tetrahydrocannabivarin (THCV), salts and derivatives thereof.

5. The oral chewable tablet according to claim 1 , wherein the non-DC sweetener particles are selected from the group consisting of non-DC particles of erythritol, maltitol, xylitol, isomalt, lactitol, mannitol, and combinations thereof.

6. The oral chewable tablet according to claim 1 , wherein the non-DC sweetener particles are selected from the group consisting of non-DC particles of dextrose, sucrose, maltose, fructose, lactose, and combinations thereof.

7. The oral chewable tablet according to claim 1 , wherein said DC particles are selected from the group consisting of DC particles of sorbitol, erythritol, xylitol, lactitol, maltitol, mannitol, isomalt, and combinations thereof.

8. The oral chewable tablet according to claim 1 , wherein said DC particles are selected from the group consisting of DC particles of dextrose, sucrose, maltose, fructose, lactose, and combinations thereof.

9. The oral chewable tablet according to claim 1 , wherein said DC particles are selected from the group consisting of DC particles of silica, microcrystalline cellulose, cellulose, silicified microcrystalline cellulose, clay, talc, starch, pregelatinized starch, calcium carbonate, dicalcium phosphate, magnesium carbonate, magnesium-alumino-metasilicates, hyper porous silica and mixtures thereof.

10. The oral chewable tablet according to claim 1 , wherein the tablet further comprises a self-emulsifying system that when hydrated with saliva upon oral administration forms an emulsion for delivery of the one or more cannabinoids to a mucosal surface.

11. The oral chewable tablet according to claim 10 , wherein the self-emulsifying system comprises one or more emulsifiers and one or more oil carriers.

12. The oral chewable tablet according to claim 10 , wherein the self-emulsifying system comprises one or more emulsifiers, one or more oil carriers and one or more solubilizers.

13. The oral chewable tablet according to claim 1 , wherein the one or more cannabinoids are present in a premixture.

14. The oral chewable tablet according to claim 13 , wherein the premixture is present in an amount of 5 to 50% by weight of the tablet.

15. The oral chewable tablet according to claim 1 , wherein said population of particles is comprised in a first module of the tablet and a second population of particles is comprised in a second module of the tablet.

16. The oral chewable tablet according to claim 15 , wherein the second module comprises DC particles in an amount of at least 50% by weight of the second module.

17. The oral chewable tablet according to claim 1 , wherein the one or more cannabinoids comprise at least one phytocannabinoid that forms part of an extract.

18. The oral chewable tablet according to claim 1 , wherein the one or more cannabinoids comprise at least one isolated cannabinoid.

19. The oral tablet according to claim 1 , wherein the one or more cannabinoids comprise at least one endocannabinoid or endocannabinoid-like compound.

20. The oral tablet according to claim 1 , wherein the one or more cannabinoids comprise at least one water-soluble cannabinoid.

21. An oral chewable tablet for delivery of cannabinoids comprising a population of particles and one or more cannabinoids, the population of particles comprising a) directly compressible (DC) particles and b) non-directly compressible (non-DC) sweetener particles, the non-DC particles providing the tablet with a plurality of discrete non-DC areas, wherein the tablet has a weight ratio between said non-DC sweetener particles and said DC particles, which is between 0.3 and 0.7.

22. An oral chewable tablet for delivery of cannabinoids comprising a population of particles and one or more cannabinoids, the population of particles comprising a) directly compressible (DC) particles and b) non-directly compressible (non-DC) sweetener particles, the non-DC particles providing the tablet with a plurality of discrete non-DC areas, wherein the one or more cannabinoids are present in a premixture and reversibly adsorbed onto one or more solid particles, wherein a weight ratio of the one or more cannabinoids relative to the one or more solid particles is from 1:30 to 1:1.

23. An oral chewable tablet for delivery of cannabinoids comprising a population of particles and one or more cannabinoids, the population of particles comprising non-directly compressible (non-DC) sweetener particles, the non-DC sweetener particles providing the tablet with a plurality of discrete non-DC areas, and the one or more cannabinoids being dispersed within a matrix of the non-DC sweetener particles, wherein the tablet comprises said non-DC sweetener particles in an amount of at least 10% by weight of the tablet.