IP Library › Granted Patent US 11,617,900
Granted Patent B2
US 11,617,900 · App. 17/182,601 · Granted Apr 4, 2023

Apparatus, method, and system for selectively effecting and/or killing bacteria

Inventors: Gerhard Randers-Pehrson (Ossining, NY); David Jonathan Brenner (New York, NY); Alan Bigelow (New York, NY)
Assignee: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
A61N5/0624A61B18/18A61L2/0047A61N5/0601A61B2018/1807A61N5/0616A61N2005/0654A61N2005/0655A61N2005/0661A61N2005/0667
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Quick Facts
Patent No.
US 11,617,900
App. No.
17/182,601
Granted
Apr 4, 2023
Kind
B2
Abstract

Certain exemplary embodiments can provide an apparatus and method for generating at least one radiation. The exemplary apparatus and/or method can selectively kill and/or affect at least one bacteria. For example, a radiation source first arrangement can be provided which is configured to generate at least one radiation having one or more wavelengths provided in a range of about 190 nanometers (nm) to about 230 nm, and at least one second arrangement can be provided which is configured to prevent the at least one radiation from having any wavelength that is outside of the range.

Claims (29)

1. A method for selectively killing or destroying at least one bacteria, comprising:

generating, with at least one ultraviolet (UV) source, at least one bactericidal radiation configured to selectively kill or destroy the at least one bacteria on or within a body, while avoiding harm to cells of the body, wherein the at least one bactericidal radiation has at least one wavelength that is in a range of 190 nanometers (nm) to 230 nm, and wherein a peak wavelength of the at least one bactericidal radiation is at least one of approximately at 207 nm or approximately at 222 nm;

filtering, with a filter arrangement comprising at least one of a band pass filter or a combination of a low pass filter and a high pass filter, the at least one bactericidal radiation to prevent all UVC wavelengths that are outside of the range from passing through the filter arrangement;

allowing all wavelengths in the range of 190 nm to 230 nm to pass through the filter arrangement and be provided to the body; and

irradiating the at least one bacteria using the allowed wavelengths and selectively killing or destroying the at least one bacteria,

wherein the at least one bacteria has a cell diameter that is less than 1 μm, and wherein the generation or the filtering comprises modifying the at least one bactericidal radiation to penetrate and kill or destroy the at least one bacteria while avoiding harm to cells of the body.

2. The method of claim 1 , further comprising directing the at least one bactericidal radiation using the at least one UV source.

3. The method of claim 1 , wherein the at least one UV source includes at least one of a krypton-bromine lamp or a krypton-chlorine lamp.

4. The method of claim 1 , wherein the filter arrangement includes at least one of a chemical filter or a dielectric filter.

5. The method of claim 1 , wherein the filtering the at least one bactericidal radiation to prevent all UVC wavelengths that are outside of the range from passing through the filter arrangement includes filtering out the at least one bactericidal radiation that has a peak wavelength outside of the range.

6. The method of claim 1 , wherein the selectively killing or destroying the at least one bacteria includes, at a same time, avoiding harm to the cells of the body.

7. The method of claim 1 , further comprising providing the at least one bactericidal radiation from within a housing through a window thereof in a first direction that is approximately parallel to a second direction of irradiation of the at least one radiation through the window.

8. The method of claim 1 , wherein the selectively killing or destroying at least one bacteria is performed at a medical treatment site or in a medical treatment environment.

9. The method of claim 1 , further comprising providing a fluorescing visible light to indicate that the at least one UV source is operating with the filter arrangement.

10. A method for selectively killing or destroying at least one bacteria, comprising:

generating, with at least one ultraviolet (UV) source, at least one bactericidal radiation configured to selectively kill or destroy the at least one bacteria on or within a body, while avoiding harm to cells of the body, wherein the at least one bactericidal radiation has at least one peak wavelength that is in a range of 190 nanometers (nm) to 230 nm;

filtering, with a filter arrangement comprising at least one of a band pass filter or a combination of a low pass filter and a high pass filter, the at least one bactericidal radiation to prevent all UVC wavelengths that are outside of the range from passing through the filter arrangement;

allowing all wavelengths in the range of 190 nm to 230 nm to pass through the filter arrangement and be provided to the body; and

irradiating the at least one bacteria using the allowed wavelengths and selectively killing or destroying the at least one bacteria,

wherein the at least one of bacteria has a cell diameter that is less than 1 μm, and wherein the generating or the filtering comprises modifying the at least one bactericidal radiation to penetrate and kill or destroy the at least one bacteria while avoiding harm to cells of the body.

11. The method of claim 10 , further comprising directing the at least one bactericidal radiation using the at least one UV source.

12. The method of claim 10 , wherein the at least one UV source includes at least one of a krypton-bromine lamp or a krypton-chlorine lamp.

13. The method of claim 10 , wherein the filter arrangement includes at least one of a chemical filter or a dielectric filter.

14. The method of claim 10 , wherein the selectively killing or destroying at least one bacteria includes selectively killing or destroying the at least one bacteria at a medical treatment site or in a medical treatment environment.

15. The method of claim 10 , further comprising providing a fluorescing visible light to indicate that the at least one UV source is operating with the filter arrangement.

16. An apparatus for killing or destroying at least one bacteria, comprising:

an excilamp configured to generate at least one bactericidal radiation configured to kill or destroy the at least one bacteria, wherein the at least one bactericidal radiation has a peak wavelength provided in a range of 190 nanometers (nm) to 230 nm; and

at least one filter arrangement configured to: (i) prevent all UVC wavelengths that are outside of the range from passing through the at least one filter arrangement and (ii) allow wavelengths in the range to pass through the at least one filter arrangement,

wherein the at least one of bacteria has a cell diameter that is less than 1 μm, and wherein the at least one filter arrangement is configured to modify the at least one bactericidal radiation to penetrate and kill or destroy the at least one bacteria while avoiding harm to cells of the body.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 23, 2021
From: RANDERS-PEHRSON, GERHARD; BRENNER, DAVID JONATHAN; BIGELOW, ALAN
To: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Reel/Frame 055371/0509 →
Continuity (6)
Continuation 16453565 · Jun 26, 2019
Continuation 14886635 · Oct 19, 2015
Division 14021631 · Sep 9, 2013
Continuation In Part PCTUS2012027963 · Mar 7, 2012
Provisional Application 61450038 · Mar 7, 2011
Related Publication 20210252305A1 · Aug 19, 2021