IP Library › Granted Patent US 12,033,755
Granted Patent B2
US 12,033,755 · App. 17/198,318 · Granted Jul 9, 2024

Method and arrangement for identifying similar pre-stored medical datasets

Inventors: David Jean Winkel (Basel, CH); Bin Lou (Princeton Junction, NJ); Dorin Comaniciu (Princeton Junction, NJ); Ali Kamen (Skillman, NJ)
Assignee: Siemens Healthineers AG
G16H50/20G16H10/40G16H20/30G16H30/00
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Quick Facts
Patent No.
US 12,033,755
App. No.
17/198,318
Granted
Jul 9, 2024
Kind
B2
Abstract

Similar pre-stored medical datasets are identified by comparison with a current case dataset. A current case dataset is provided and includes radiological data of a patient. A number of pre-stored medical datasets each including radiological data of other patients are provided. Each case dataset is evaluated according to a predefined AI-based method to obtain a number of definitive features for that case dataset. The definitive features of the current case dataset are compared with the definitive features of each pre-stored medical dataset to identify a number of pre-stored medical datasets most similar to the current case dataset. The identified number of most similar pre-stored medical datasets are output.

Claims (29)

1. A method for identifying similar pre-stored medical datasets for comparison with a current case dataset, the method comprising:

providing a current case dataset comprising radiological data of a patient;

providing a number of pre-stored medical datasets each comprising radiological data of other patients;

obtaining features for the current case dataset and each of the number of pre-stored medical datasets based on an evaluation of the current case dataset and the number of pre-stored medical datasets according to a predefined AI-based method comprising a convolutional neural network configured to evaluate datasets to obtain a vector of definitive abstract features, the convolutional neural network trained by comparing a predicted risk factor with a histologically determined Gleason score as ground truth;

identifying a number of pre-stored medical datasets most similar to the current case dataset based on a comparison of the features of the current case dataset with the features of each of the number of pre-stored medical datasets; and

outputting the identified number of most similar pre-stored medical datasets.

2. The method according to claim 1 , wherein obtaining comprises obtaining by the evaluation of the current case and pre-stored medical datasets with respect to tissue abnormalities.

3. The method according to claim 1 , wherein each current case and pre-stored medical dataset comprises multi-parametric MRI data.

4. The method according to claim 1 , wherein each current case and pre-stored medical dataset comprises values of one or more of the following parameters: PSA value, PSA density, DRU score, EPE score, lymph node status, and/or patient age.

5. The method according to claim 1 , wherein each current case and pre-stored medical dataset comprises values of one or more of the following radiologically determined parameters: PI-RADS value, lesion size, lesion location and/or organ volume.

6. The method according to claim 1 , wherein the predefined AI-based method obtains a single scalar value for a risk score as a feature in the evaluation of each current case and pre-stored medical dataset.

7. The method according to claim 1 , wherein the predefined AI-based method obtains, as part of the evaluation, a vector of features comprising values for one or more of the following radiomic parameters: lesion size, lesion intensity, lesion shape, lesion texture, wavelet transformation.

8. The method according to claim 1 , wherein the predefined AI-based method obtains, as part of the evaluation, a vector of features comprising one or more values for a risk score and values for parameters of a task-specific fingerprint.

9. The method according to claim 1 , wherein the most similar pre-stored medical datasets are identified by minimum distance measures between the current case dataset and the pre-stored medical datasets.

10. The method according to claim 2 , wherein obtaining comprises obtaining by the evaluation of the current case and pre-stored medical datasets with respect to tissue abnormalities comprising indications of prostate cancer.

11. An evaluation arrangement for identifying similar pre-stored medical datasets for comparison with a current case dataset, the evaluation arrangement comprising:

a first interface for receiving a current case dataset comprising radiological data of a patient;

a second interface to a number of pre-stored medical datasets each comprising radiological data of another patient;

a processor operating pursuant to instructions stored in a memory, the instruction comprising instruction to:

evaluate each current case and pre-stored medical dataset according to a predefined AI-based method to obtain a number of features for each respective case dataset, wherein the number of features comprise a vector of definitive features including values for one or more of the following radiomic parameters or parameter groups: lesion size, lesion intensity, lesion shape, lesion texture, and wavelet transformation, wherein the predefined AI-based method comprises a convolutional neural network trained by comparing a predicted risk factor with a histologically determined Gleason score as ground truth; and

identify a number of pre-stored medical datasets most similar to the current case dataset based on a comparison of the features of the current case dataset with the features of each pre-stored medical dataset; and

an output interface for outputting the identified number of most similar pre-stored medical datasets.

12. The evaluation arrangement of claim 11 further comprising a screen for displaying the identified datasets.

13. A non-transitory computer-readable medium on which program elements are stored that can be read and executed by a computer, the non-transitory computer-readable medium having stored thereon instructions for:

providing a current case dataset comprising radiological data of a patient;

providing a number of pre-stored medical datasets each comprising radiological data of other patients;

obtaining a number of features including one or more values for a risk score and values for parameters of a task-specific fingerprint for each respective case dataset based on an evaluation of each current case and pre-stored medical dataset according to a predefined AI-based method, wherein the AI-based method comprises a convolutional neural network configured to evaluate datasets to obtain a vector of definitive abstract features, the convolutional neural network trained by comparing a predicted risk factor with a histologically determined Gleason score as ground truth;

identifying a number of pre-stored medical datasets most similar to the current case dataset based on a comparison of the features of the current case dataset with the features of each pre-stored medical dataset; and

outputting the identified number of most similar pre-stored medical datasets.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2023
From: SIEMENS HEALTHCARE GMBH
To: SIEMENS HEALTHINEERS AG
Reel/Frame 066267/0346 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2021
From: SIEMENS MEDICAL SOLUTIONS USA, INC.
To: SIEMENS HEALTHCARE GMBH
Reel/Frame 055931/0764 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 22, 2021
From: WINKEL, DAVID JEAN; LOU, BIN; COMANICIU, DORIN; KAMEN, ALI
To: SIEMENS MEDICAL SOLUTIONS USA, INC.
Reel/Frame 055670/0032 →
Priority Claims (1)
DE 102020207943.9 · Jun 26, 2020 · national
Continuity (1)
Related Publication 20210407674A1 · Dec 30, 2021