IP Library Granted Patent US 11,155,563
Granted Patent B2
US 11,155,563 · App. 17/213,093 · Granted Oct 26, 2021

Macrocyclic compounds and uses thereof

Inventors: Jingrong Jean Cui (San Diego, CA); Evan W. Rogers (San Diego, CA); Jane Ung (San Diego, CA); Jeffrey Whitten (San Diego, CA); Dayong Zhai (San Diego, CA); Wei Deng (San Diego, CA); Xin Zhang (San Diego, CA); Zhongdong Huang (San Diego, CA); Jing Liu (San Diego, CA); Han Zhang (San Diego, CA)
Assignee: Turning Point Therapeutics, Inc.
C07D498/16A61P35/00C07K16/2863A61K45/06
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Quick Facts
Patent No.
US 11,155,563
App. No.
17/213,093
Granted
Oct 26, 2021
Kind
B2
Abstract

The present disclosure relates to certain macrocyclic compounds that inhibit SRC and MET, and/or CSF1R, pharmaceutical compositions containing such compounds, and methods of using such compounds to treat cancer.

Claims (5)

1. A compound having structure:

or a pharmaceutically acceptable salt thereof.

2. A compound having structure:

3. A pharmaceutical composition comprising a compound having structure:

or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable diluent, carrier or excipient.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 30, 2021
From: CUI, JINGRONG JEAN; ROGERS, EVAN W.; UNG, JANE; WHITTEN, JEFFREY; ZHAI, DAYONG; DENG, WEI; ZHANG, XIN; HUANG, ZHONGDONG; LIU, JING; ZHANG, HAN
To: TURNING POINT THERAPEUTICS, INC.
Reel/Frame 056724/0262 →
Continuity (4)
Continuation 16634289
Provisional Application 62700990 · Jul 20, 2018
Provisional Application 62538193 · Jul 28, 2017
Related Publication 20210214373A1 · Jul 15, 2021
Cited By (1)
US 12,606,571