IP Library › Granted Patent US 12,144,519
Granted Patent B2
US 12,144,519 · App. 17/214,323 · Granted Nov 19, 2024

Transperineal prostate biopsy and treatment methods

Inventor: Matthew J. Allaway (Cumberland, MD)
Assignee: Corbin Clinical Resources, LLC
A61B17/3403A61B8/0841A61B8/12A61B10/0241A61B2017/3405A61B2017/3411A61B2017/3413A61B2090/3925A61B2090/3933A61B2090/3954A61B2090/3966
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Quick Facts
Patent No.
US 12,144,519
App. No.
17/214,323
Granted
Nov 19, 2024
Kind
B2
Abstract

A method of performing a therapy on a prostate of a patient via transperineal access. The therapy uses an ultrasound probe. The method includes positioning a pair of stabilization members of a needle guide adjacent the perineum. The pair of stabilization members spaced apart from each other and supporting a platform configured to slide along a portion of a length of the pair of stabilization members. The needle guide is coupled to the ultrasound probe. The method further includes coupling an access needle to the platform, and sliding the platform and the access needle relative to the pair of stabilization members and the ultrasound probe so the access needle extends into the perineum. And the method further includes, using the access needle as a conduit, injecting a radiation blocking substance between the rectum and the prostate.

Claims (45)

1. A method of performing a therapy on a prostate of a patient via transperineal access, the therapy using an ultrasound probe, the patient including a rectum and a perineum, the method comprising:

positioning a pair of stabilization members of a needle guide adjacent the perineum, the pair of stabilization members spaced apart from each other and supporting a platform configured to slide along a portion of a length of the pair of stabilization members, the needle guide coupled to the ultrasound probe;

coupling an access needle to the platform;

sliding the platform and the access needle relative to the pair of stabilization members and the ultrasound probe so the access needle extends into the perineum; and

using the access needle as a conduit, injecting a radiation blocking substance between the rectum and the prostate.

2. The method of claim 1 , further comprising: providing radiation therapy to the prostate.

3. The method of claim 1 , wherein the radiation blocking substance comprises a hydrogel.

4. The method of claim 1 , further comprising: inserting a needle through the access needle, the radiation blocking substance being injected through the needle.

5. The method of claim 1 , wherein injecting the radiation blocking substance between the rectum and the prostate spaces the rectum and the prostate apart from each other.

6. The method of claim 1 , further comprising inserting a needle through the access needle and into a first location within the prostate.

7. The method of claim 6 , further comprising inserting the needle through the access needle and into a second location within the prostate, the second location being different than the first location.

8. The method of claim 7 , wherein the access needle remains positioned within the perineum during the insertion of the needle into both of the first and second locations.

9. The method of claim 1 , wherein positioning the pair of stabilization members of the needle guide proximate of the perineum comprises contacting a distal end of the pair of stabilization members with a perineal skin of the patient.

10. The method of claim 1 , wherein the access needle is generally parallel to a longitudinal axis of the ultrasound probe when the biopsy guide is secured to the ultrasound probe, and the pair of stabilization members are laterally spaced apart from each other and from a plane intersecting the access needle and the longitudinal axis of the ultrasound probe.

11. The method of claim 1 , wherein the radiation blocking substance comprises a hydrogel.

12. A method of performing a therapy on a prostate of a patient via transperineal access, the therapy using an ultrasound probe, the patient including a rectum and a perineum, the method comprising:

inserting an access needle through the perineum, the access needle engaged with a displacement member that is configured to slide on a pair of stabilization members of a biopsy guide, the access needle being centrally positioned between the pair of stabilization members when the access needle is engaged with the displacement member;

inserting a needle through the access needle; and

forming a radiation barrier in a space between the prostate and the rectum by injecting a radiation blocking substance into the space via the needle positioned through the access needle.

13. The method of claim 12 , further comprising contacting a distal end of the pair of stabilization members against a perineal skin of the patient prior to inserting the access needle into the perineum.

14. The method of claim 13 , further comprising positioning the perineal skin with the distal end of the pair of stabilization members so as to orient the access needle for injection of the radiation blocking substance.

15. The method of claim 12 , wherein inserting the access needle into the perineum comprises sliding the access needle and platform along a portion of a length of the pair of stabilization members.

16. The method of claim 12 , further comprising securing the platform at a distal position along the length of the pair of stabilization members.

17. The method of claim 12 , further comprising providing radiation therapy to the prostate.

18. A method of performing a therapy on a prostate of a patient via transperineal access, the prostate having a cancerous area therein, the therapy using an ultrasound probe, the patient including a rectum and a perineum, the method comprising:

positioning a needle guide adjacent the perineum, the needle guide supporting a platform configured to slide along a portion of a length of the needle guide, the platform including at least one hole, the needle guide coupled to the ultrasound probe;

inserting an access needle through the at least one hole in the platform;

inserting the access needle into the perineum;

using the access needle as a guide, inserting a tip of an instrument through the access needle and into a first location of the prostate within the cancerous area;

providing a first instance of focal therapy to the cancerous area at the first location of the prostate via the instrument;

positioning a trajectory of the access needle to intersect with a second location of the prostate within the cancerous area; and

providing a second instance of focal therapy to the cancerous area at the second location of the prostate via the instrument.

19. The method of claim 18 , wherein the instrument is a conduit, and providing a first instance of focal therapy further includes injecting water vapor into the prostate via the conduit.

20. The method of claim 19 , wherein the conduit is part of a water vapor delivery system including a control system and a water reservoir.

21. The method of claim 19 , further comprising retracting the conduit from the prostate after the first instance of focal therapy is provided, inserting the tip of the conduit through the access needle and into the prostate at the second location, and providing the second instance of focal therapy by injecting water vapor into the prostate via the conduit at the second location.

22. The method of claim 21 , wherein the access needle remains in the perineum between the first and second instances of focal therapy.

23. The method of claim 18 , further comprising retracting the access needle from the prostate after the second instance of focal therapy is provided.

24. The method of claim 18 , wherein the instrument is a thermotherapy instrument.

25. The method of claim 18 , wherein the instrument is a cryoablation instrument.

26. The method of claim 18 , wherein the instrument is a radiofrequency instrument.

27. The method of claim 18 , wherein the cancerous area includes a tumor.

28. The method of claim 18 , wherein the needle guide includes a pair of stabilization members spaced apart from each other.

29. The method of claim 28 , wherein the at least one hole of the platform includes a first hole and a second hole, the first hole positioned between the pair of stabilization members and the ultrasound probe, the second hole positioned above the pair of stabilization members.

30. The method of claim 18 , wherein inserting the access needle into the perineum includes sliding the platform and the access needle relative to the pair of stabilization members and the ultrasound probe so the access needle extends into the perineum.

31. The method of claim 18 , wherein the access needle remains in the perineum between the first and second instances of focal therapy.

Assignments (6)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 10, 2026
From: CORBIN CLINICAL RESOURCES, INC.
To: BOSTON SCIENTIFIC SCIMED, INC.
Reel/Frame 075734/0844 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 10, 2026
From: CORBIN CLINICAL RESOURCES, LLC
To: CORBIN CLINICAL RESOURCES, INC.
Reel/Frame 075833/0246 →
RELEASE OF SECURITY INTEREST Recorded May 12, 2025
From: FIRST UNITED BANK & TRUST
To: CORBIN CLINICAL RESOURCES, LLC
Reel/Frame 071092/0170 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 9, 2023
From: ALLAWAY, MATTHEW J.
To: CORBIN CLINICAL RESOURCES, LLC
Reel/Frame 065513/0731 →
SECURITY INTEREST Recorded May 27, 2022
From: CORBIN CLINICAL RESOURCES, LLC
To: FIRST UNITED BANK & TRUST
Reel/Frame 060039/0301 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 22, 2021
From: ALLAWAY, MATTHEW J.
To: CORBIN CLINICAL RESOURCES, LLC
Reel/Frame 056944/0186 →
Continuity (6)
Continuation In Part 16991150 · Aug 12, 2020
Continuation 14874104 · Oct 2, 2015
Continuation In Part 14677286 · Apr 2, 2015
Provisional Application 63005831 · Apr 6, 2020
Provisional Application 61974826 · Apr 3, 2014
Related Publication 20210338267A1 · Nov 4, 2021
Cited By (1)
US 12,502,201