IP Library › Granted Patent US 12,605,150
Granted Patent B2
US 12,605,150 · App. 17/226,738 · Granted Apr 21, 2026

Systems, devices, and methods for coring tissue

Inventors: William Cohn (Bellaire, TX); Terry Daglow (Houston, TX); Matthew Kuhn (Houston, TX); Jonathan Melchor (Warwick, RI); Theodore Mick (Houston, TX); Chris Mills (Houston, TX); Steven Nguyen (Cypress, TX); Jorge Salazar (New York, NY)
Assignee: Prana Thoracic, Inc.
A61B10/0233A61B17/320092A61B2017/320044A61B2017/320095
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Quick Facts
Patent No.
US 12,605,150
App. No.
17/226,738
Filed
Apr 9, 2021
Granted
Apr 21, 2026
Kind
B2
Art Unit
3794
USPC
600/567
Abstract

A method for removing tissues may comprise disposing a tissue resection device at a target tissue site, causing the tissue resection device to resect a core of tissue from the target tissue site, removing the core of tissue from the body, wherein the removing the core of tissue from the body creates a core cavity at the target tissue site.

Claims (45)

1 . A method for coring tissue, the method comprising: disposing a tissue resection device near a target tissue site; rotating a helical coil of the tissue resection device distally through tissue towards the target tissue site; clamping a portion of tissue between a first electrode of a first clamping element and a second electrode of a second clamping element of the tissue resection device, the second electrode being arranged proximal to the first electrode and configured to advance toward the first electrode to clamp the portion of tissue; sealing the portion of tissue clamped between the first electrode and the second electrode by energizing at least one of the first electrode or the second electrode; advancing a cutting element slidably disposed within the second clamping element of the tissue resection device to cut the portion of tissue to form a section of cored tissue; repeating the rotating, the clamping, the sealing, and the advancing steps until the cored tissue is a predetermined size; and removing, after the cored tissue is the predetermined size, the cored tissue from the body, wherein the removing the cored tissue from the body creates a cored cavity at the target tissue site.

2 . The method of claim 1 , wherein the cored tissue comprises at least a portion of a tissue lesion.

3 . The method of claim 1 , further comprising disposing a sleeve to provide access to the target tissue site.

4 . The method of claim 3 , wherein the sleeve comprises a deployable trocar.

5 . The method of claim 3 , wherein the sleeve comprises electrodes that are configured to seal or ablate adjacent the target tissue site.

6 . The method of claim 1 , further comprising delivering at least one of radiofrequency energy, chemotherapy, microwave energy, thermal energy, or ultrasonic energy to at least a portion of a wall defining the cored cavity.

7 . The method of claim 1 , further comprising:

activating, after the cored tissue is the predetermined size, a snare element to sever the cored tissue such that the cored tissue can be removed from the body.

8 . The method of claim 7 , wherein the activating the snare element includes:

mechanically transecting the cored tissue with the snare element.

9 . The method of claim 1 , wherein the sealing is effected using radiofrequency energy.

10 . The method of claim 1 , further comprising:

disposing, after removing the cored tissue, a fill material into the cored cavity such that at least a portion of the cored cavity is sealed.

11 . The method of claim 1 , wherein the first electrode is disposed on a proximal surface of the helical coil.

12 . The method of claim 11 , wherein the clamping the portion of tissue between the first electrode and the second electrode includes:

causing the second electrode to close against the helical coil.

13 . The method of claim 1 , wherein the clamping the portion of tissue occurs after the rotating the helical coil, the sealing the portion of tissue occurs after the clamping the portion of tissue, and the advancing the cutting element occurs after the sealing the portion of tissue.

14 . A method for coring tissue, the method comprising: disposing a tissue resection device near a target tissue site; rotating a helical coil coupled to a first tube of the tissue resection device distally through tissue towards the target tissue site; advancing a distal edge of a second tube of the tissue resection device towards the target tissue site such that a portion of tissue is clamped between a first electrode disposed on a proximal surface of the helical coil and a second electrode disposed on the distal edge of the second tube of the tissue resection device; and energizing at least one of the first electrode or the second electrode with radiofrequency energy; advancing a cutting element disposed within the second tube of the tissue resection device to cut the portion of tissue to form a section of cored tissue.

15 . The method of claim 14 , further comprising:

rotating, after the advancing the cutting element, the helical coil further towards the target tissue site.

16 . The method of claim 14 , further comprising repeating the rotating, the clamping, the energizing, and the advancing a cutting element steps a plurality of times until the cored tissue is a predetermined size.

17 . The method of claim 16 , further comprising:

activating, after the cored tissue is the predetermined size, a snare element to sever the cored tissue such that the cored tissue can be removed from a body of a patient.

18 . The method of claim 16 , further comprising:

anchoring to the target tissue site prior to rotating the helical coil, wherein the cored tissue includes the anchored target tissue site.

19 . The method of claim 14 , further including:

sensing a presence of tissue at an end effector, the end effector including the first electrode and the second electrode; and

energizing, when the presence of tissue is detected, at least one of the first electrode or the second electrode with radiofrequency energy.

20 . The method of claim 14 , wherein the energizing at least one of the first electrode or the second electrode with radiofrequency energy includes:

sealing blood vessels in the portion of tissue clamped between the first electrode and the second electrode.

21 . The method of claim 14 , wherein the first tube is an outer tube, the second tube is a central tube slidably disposed in the outer tube.

22 . The method of claim 14 , wherein the first electrode is disposed on a planar portion of the helical coil such that a surface profile of the first electrode and a surface profile of the second electrode are substantially matching.

23 . A method for coring tissue, the method comprising: disposing a tissue resection device near a target tissue site; rotating a helical coil of the tissue resection device distally through tissue towards the target tissue site; clamping, after rotating the helical coil, a portion of tissue between a first electrode and a second electrode of the tissue resection device by advancing the second electrode distally toward the first electrode to clamp the portion of tissue between the first electrode and the second electrode, the second electrode being disposed on a distal edge of a tube; sealing, after the clamping, the portion of tissue clamped between the first electrode and the second electrode by energizing at least one of the first electrode or the second electrode with radiofrequency energy; and advancing, after the sealing, a cutting element slidably disposed in the tube of the tissue resection device to cut sealed tissue to form a section of cored tissue.

24 . The method of claim 23 , wherein the first electrode is disposed on a proximal surface of the helical coil and the second electrode is arranged proximal to the first electrode.

25 . The method of claim 24 , wherein the first electrode is disposed on a planar surface of the helical coil such that a surface profile of the first electrode and a surface profile of the second electrode are substantially matching.

26 . The method of claim 24 , wherein the clamping the portion of tissue between the first electrode and the second electrode includes causing the second electrode to close against the helical coil.

27 . The method of claim 24 , wherein the tube is a central tube, the helical coil is coupled to an outer tube, and the central tube is slidably disposed in the outer tube.

28 . The method of claim 23 , further comprising:

repeating the rotating, the clamping, the sealing, and the advancing steps to form the cored tissue until the cored tissue is a predetermined size.

29 . The method of claim 28 , further comprising: anchoring an anchor device to the target tissue site prior to rotating the helical coil.

30 . The method of claim 28 , further comprising:

activating, after the cored tissue is the predetermined size, a snare element to pull and sever the cored tissue.

31 . The method of claim 30 , further comprising:

removing, after activating the snare element to sever the cored tissue, the cored tissue from a body of a patient to create a cored cavity at the target tissue site; and

disposing a fill material into the cored cavity such that at least a portion of the cored cavity is sealed.

Assignments (3)
NUNC PRO TUNC ASSIGNMENT Recorded Jan 30, 2026
From: COHN, WILLIAM; DAGLOW, TERRY; KUHN, MATTHEW; NGUYEN, STEVEN; SALAZAR, JORGE; MILLS, CHRIS; MELCHOR, JONATHAN
To: ETHICON, INC.
Reel/Frame 074537/0432 →
NUNC PRO TUNC ASSIGNMENT Recorded Jan 30, 2026
From: MICK, THEODORE
To: ETHICON, INC.
Reel/Frame 073643/0361 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 18, 2022
From: ETHICON, INC.
To: PRANA THORACIC, INC.
Reel/Frame 061820/0056 →
Continuity (4)
Continuation In Part 16512628 · Jul 16, 2019
Continuation In Part 16512616 · Jul 16, 2019
Provisional Application 63017724 · Apr 30, 2020
Related Publication 20210219967A1 · Jul 22, 2021
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