IP Library › Granted Patent US 12,582,517
Granted Patent B2
US 12,582,517 · App. 17/229,189 · Granted Mar 24, 2026

Sealing member for prosthetic heart valve

Inventors: Tamir S. Levi (Zikhron Yaakov, IL); Ziv Yohanan (Kfar Hahoresh, IL); David Maimon (Atlit, IL)
Assignee: Edwards Lifesciences Corporation
A61F2/2409A61F2/2418A61F2/243A61F2220/0091A61F2230/0054A61F2250/006A61F2250/0069A61L2430/20
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Quick Facts
Patent No.
US 12,582,517
App. No.
17/229,189
Granted
Mar 24, 2026
Kind
B2
Abstract

A prosthetic heart valve can include a frame, a valve component, a sealing member, and a retaining member. The frame can be radially compressible and expandable between a radially-compressed configuration and a radially-expanded configuration. The valve component can be disposed within and coupled to the frame and have a plurality of leaflets. The sealing member can have a plurality of ribs and a plurality of connectors. The ribs can be coupled to and extend radially outwardly from the frame when the frame is in the radially-expanded configuration. The connectors can be coupled to and extend radially between the frame and the ribs. The sealing member can be configured to reduce or prevent perivalvular leakage around the prosthetic heart valve. The retaining member can be coupled to the frame and the sealing member and can retain the sealing member at a desired spacing relative to the frame.

Claims (25)

1 . A prosthetic heart valve comprising:

a frame having an inflow end portion, an outflow end portion, an intermediate portion disposed between the inflow end portion and the outflow end portion, and a plurality of struts, wherein the frame is radially collapsible and expandable between a radially-compressed configuration and a radially-expanded configuration;

a valve component disposed within and coupled to the frame and having a plurality of leaflets; and

a sealing member including a plurality of ribs and a plurality of connectors, wherein the plurality of ribs is coupled to and extends radially outwardly from the frame when the frame is in the radially-expanded configuration, wherein the plurality of connectors is coupled to the frame and the plurality of ribs; and

a retaining member extending radially outwardly from the frame to the sealing member, wherein the retaining member is disposed radially outwardly from the plurality of ribs and the plurality of connectors and configured to restrict radial expansion of the plurality of ribs and the plurality of connectors.

2 . The prosthetic heart valve of claim 1 , wherein the plurality of connectors includes a plurality of first connectors and a plurality of second connectors, wherein the plurality of first connectors is coupled to the frame and the plurality of ribs, circumferentially aligned with the plurality of ribs, and extends radially between the frame and the plurality of ribs, and wherein the plurality of second connectors is coupled to the frame, the plurality of ribs, and the plurality of first connectors.

3 . The prosthetic heart valve of claim 2 , wherein each second connector of the plurality of second connectors is at least substantially perpendicular to one or more first connectors of the plurality of first connectors.

4 . The prosthetic heart valve of claim 1 , wherein the retaining member is a flexible cord.

5 . The prosthetic heart valve of claim 1 , further comprising a skirt mounted on the frame, and wherein each connector of the plurality of connectors has an inner longitudinally-extending edge sutured to the skirt and an outer longitudinally-extending edge contacting the one or more retaining members.

6 . The prosthetic heart valve of claim 1 , wherein the plurality of connectors comprises PET, PTFE, ePTFE, polyurethane, or polyester.

7 . A prosthetic heart valve, comprising:

a frame having an inflow end portion, an outflow end portion, an intermediate portion disposed between the inflow end portion and the outflow end portion, and a plurality of struts, wherein the frame is radially compressible and expandable between a radially-compressed configuration and a radially-expanded configuration;

a valve component disposed within and coupled to the frame and having a plurality of leaflets; and

a plurality of ribs;

a plurality of connectors; and

and a retaining member,

wherein the plurality of ribs is coupled to and extends radially outwardly from the frame when the frame is in the radially-expanded configuration, wherein each connector of the plurality of connectors is coupled to and extends radially between the frame and a respective rib of the plurality of ribs, wherein the retaining member is coupled to the frame and the plurality of ribs so as to limit radial expansion of the plurality of ribs relative to the frame, and wherein the plurality of connectors is configured to reduce or prevent perivalvular leakage around the prosthetic heart valve.

8 . The prosthetic heart valve of claim 7 , further comprising a fabric skirt coupled to the plurality of struts of the frame, and wherein the plurality of connectors is sutured to the fabric skirt and extends radially outwardly therefrom.

9 . The prosthetic heart valve of claim 7 , wherein the retaining member is a flexible cord.

10 . The prosthetic heart valve of claim 9 , wherein the flexible cord is a nylon thread.

11 . The prosthetic heart valve of claim 9 , wherein the flexible cord is a stainless-steel wire.

12 . The prosthetic heart valve of claim 9 , further comprising a skirt mounted on the frame, and wherein each connector of the plurality of connectors has an inner longitudinally-extending edge sutured to the skirt and an outer longitudinally-extending edge contacting the one or more retaining members.

13 . The prosthetic heart valve of claim 9 , wherein the plurality of connectors comprises PET, PTFE, ePTFE, polyurethane, or polyester.

14 . The prosthetic heart valve of claim 12 , wherein the flexible cord is a nylon thread.

15 . The prosthetic heart valve of claim 12 , wherein the flexible cord is a stainless-steel wire.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 11, 2021
From: LEVI, TAMIR S.; YOHANAN, ZIV; MAIMON, DAVID
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 056207/0020 →
Continuity (3)
Continuation 16114518 · Aug 28, 2018
Provisional Application 62554933 · Sep 6, 2017
Related Publication 20210228342A1 · Jul 29, 2021
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