IP Library Granted Patent US 11,318,174
Granted Patent B2
US 11,318,174 · App. 17/240,433 · Granted May 3, 2022

Probiotics for use in the prevention or treatment of illness and/or symptoms associated with coronaviruses

Inventors: Sebastien Guery (Munich, DE); Markus Lehtinen (Vantaa, FI); Sinikka Anneli Latvala (Helsinki, FI); Liisa Lehtoranta (Sundsberg, FI); Bryan-James Zabel (Madison, WI); Wesley William Morovic (Edgerton, WI); Charles Budinoff (Oregon, WI); Scott D. Power (Woodside, CA)
A61K35/745A61K35/744A61P31/14
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Quick Facts
Patent No.
US 11,318,174
App. No.
17/240,433
Granted
May 3, 2022
Kind
B2
Abstract

This invention relates to bacterial strains, compositions comprising bacterial strains as well as methods and uses of said strains and compositions for preventing or treating illness and/or symptoms associated with a coronavirus in a subject in need thereof.

Claims (8)

1. A method for treating illness and/or symptoms in a subject infected with SARS-CoV2 coronavirus, said method comprising administering an effective amount of a composition comprising Bifidobacterium longum subsp. infantis strain Bi-26 ; Bifidobacterium animalis subsp. lactis strain B1-04 ; Lacticaseibacillus paracasei strain Lpc-37 ; Lacticaseibacillus rhamnosus strain Lr-32; and Ligilactobacillus salivarius strain Ls-33 to said subject infected with SARS-CoV2 coronavirus, wherein said administration results in decreased SARS-CoV2 viral titer in the subject.

2. The method according to claim 1 , wherein said illness is a respiratory illness.

3. The method according to claim 2 , wherein the respiratory illness is acute respiratory distress syndrome (ARDS).

4. The method according to claim 2 , wherein the respiratory illness is pneumonia.

5. The method according to claim 1 , wherein said symptoms are one or more of dyspnea, fatigue, muscle or body aches, nausea or vomiting, diarrhea, cough, fever, anosmia and/or ageusia.

6. The method according to claim 1 , wherein said or treating is achieved by stimulation of the immune system in the subject.

7. The method according to claim 1 , wherein the subject has one or more pre-existing conditions selected from the group consisting of obesity, type II diabetes, chronic lung disease or moderate to severe asthma, heart conditions, immunocompromised, chronic kidney disease and liver disease.

8. The method according to claim 1 , wherein the subject is 65 years of age or older and/or is a resident in a nursing home or long-term care facility or jail or prison.

Assignments (7)
CHANGE OF NAME Recorded Feb 6, 2024
From: DUPONT NUTRITION BIOSCIENCES APS
To: INTERNATIONAL N&H DENMARK APS
Reel/Frame 066494/0814 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 17, 2022
From: DANISCO SWEETENERS OY
To: DUPONT NUTRITION BIOSCIENCES APS
Reel/Frame 059293/0050 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 17, 2022
From: ZABEL, BRYAN-JAMES EDWIN; MOROVIC, WESLEY WILLIAM; BUDINOFF, CHARLES; POWER, SCOTT D.
To: DANISCO USA INC.
Reel/Frame 059293/0148 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 17, 2022
From: DANISCO USA INC.
To: DUPONT NUTRITION BIOSCIENCES APS
Reel/Frame 059299/0021 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 16, 2022
From: LEHTINEN, MARKUS; LATVALA, SINIKKA ANNELI; LEHTORANTA, LIISA
To: DANISCO SWEETENERS OY
Reel/Frame 059284/0869 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 16, 2022
From: DANISCO DEUTSCHLAND GMBH
To: DUPONT NUTRITION BIOSCIENCES APS
Reel/Frame 059370/0329 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 16, 2022
From: GUERY, SEBASTIEN
To: DANISCO DEUTSCHLAND GMBH
Reel/Frame 059284/0221 →