Nerve labeling compositions and uses thereof
Described herein are methods and compositions for nerve delivery molecules that carry imaging cargo or therapeutic cargo to the neurons or nerves.
1. A pharmaceutical composition, comprising:
(i) a nerve delivery molecule selected from the group consisting of:
(ii) a pharmaceutically acceptable carrier or excipient.
2. The pharmaceutical composition of claim 1 , wherein the nerve delivery molecule is:
3. The pharmaceutical composition of claim 1 , wherein the nerve delivery molecule is:
4. A method of imaging a target neuron, nerve, or tissue or external structure associated therewith, comprising:
(i) contacting the target neuron, nerve, or tissue or external structure associated therewith with a nerve delivery molecule selected from the group consisting of:
(ii) subsequently imaging the target neuron, nerve, or tissue or external structure associated therewith.
5. The method of claim 4 , wherein the nerve delivery molecule is:
6. The method of claim 4 , wherein the nerve delivery molecule is:
7. A method of imaging a target neuron, nerve, or tissue or external structure associated therewith, comprising:
(i) contacting the target neuron, nerve, or tissue or external structure associated therewith with a pharmaceutical composition comprising a nerve delivery molecule selected from the group consisting of:
a pharmaceutically acceptable carrier or excipient; and
(ii) subsequently imaging the target neuron, nerve, or tissue or external structure associated therewith.
8. The method of claim 7 , wherein the nerve delivery molecule is:
9. The method of claim 7 , wherein the nerve delivery molecule is: