IP Library Granted Patent US 11,717,790
Granted Patent B2
US 11,717,790 · App. 17/252,358 · Granted Aug 8, 2023

System for filtration and associated method

Inventors: Nityananda Maiya (Karnataka, IN); Deepak Aravind (Karnataka, IN); Fredrik Lundström (Uppsala, SE); Saameera Simha Hindupur (Karnataka, IN); Shivakumar Selvaraj (Karnataka, IN); Alagur Sahebagouda (Karnataka, IN)
Assignee: CYTIVA SWEDEN AB
B01D61/12B01D61/22B01D65/02B01D2311/04B01D2311/06B01D2311/14B01D2311/16B01D2313/48B01D2315/10B01D2315/20B01D2321/40
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Quick Facts
Patent No.
US 11,717,790
App. No.
17/252,358
Granted
Aug 8, 2023
Kind
B2
Abstract

A method includes measuring, by a flow sensor ( 70 ), a flow rate of a permeate fluid ( 48 ) flowing through a filter ( 20 ) of a membrane filtration system ( 12 ). Further, the method includes receiving, by a control unit ( 86 ), the measured flow rate of the permeate fluid ( 48 ) and determining, by the control unit ( 86 ), a first flux rate of the filter ( 20 ) based on the measured flow rate of the permeate fluid ( 48 ). Furthermore, the method includes comparing, by the control unit ( 86 ), the determined first flux rate with a first predetermined flux rate. Additionally, the method includes operating the membrane filtration system ( 12 ), by the control unit ( 86 ), in a normal mode or a flux tolerant mode based on the comparison of the determined first flux rate with the first predetermined flux rate. The flux tolerant mode of the membrane filtration system ( 12 ) is further based on a determined normalized water permeability value of the filter ( 20 ).

Claims (18)

1. A method of operation of a system comprising a membrane filtration system, the method comprising:

measuring, by a flow sensor, a flow rate of a permeate fluid flowing through a filter of the membrane filtration system;

receiving, by a control unit, a signal indicative of the measured flow rate of the permeate fluid;

determining, by the control unit, a first flux rate of the filter based on the measured flow rate signal of the permeate fluid;

comparing, by the control unit, the first flux rate with a first predetermined flux rate;

operating the membrane filtration system, by the control unit, in a normal filtration mode in response to the first flux rate being greater than or equal to the first predetermined flux rate;

operating the membrane filtration system, by the control unit, in (i) a modified filtration mode or (ii) a cleaning mode in response to the first flux rate being less than the first predetermined flux rate, wherein the cleaning mode of the membrane filtration system is further based on a determined normalized water permeability value of the filter; and

resetting the first predetermined flux rate in accordance with a change in transmembrane pressure (TMP) when the filter is operated over a number of cycles until the determined normalized water permeability value of the filter is less than a predetermined percentage of a predetermined base value of the filter.

2. The method as claimed in claim 1 , wherein operating the membrane filtration system in the modified filtration mode comprises, by the control unit, changing at least one operational parameter of the membrane filtration system.

3. The method as claimed in claim 2 , wherein the at least one operational parameter comprises at least one of a speed of a permeate pump of the membrane filtration system, a speed of a feed pump of the membrane filtration system, an actuation of a first pressure control valve of a permeate flow path of the membrane filtration system, or an actuation of a second pressure control valve of a retentate flow path of the membrane filtration system.

4. The method as claimed in claim 1 , comprising operating the membrane filtration system in the cleaning mode after the modified filtration mode in response to the first flux rate remaining less than the first predetermined flux rate after operating the membrane filtration system in the modified filtration mode.

5. The method as claimed in claim 1 , wherein operating the membrane filtration system in the cleaning mode comprises directing water through the filter to clean the filter.

6. The method as claimed in claim 5 , wherein operating the membrane filtration system in the cleaning mode comprises determining the normalized water permeability value of the filter based on a predefined flux of the filter and a determined transmembrane pressure of the filter.

7. The method as claimed in claim 6 , wherein operating the membrane filtration system in the cleaning mode comprises comparing the normalized water permeability value of the filter with a predetermined base value of the filter.

8. The method as claimed in claim 7 , wherein operating the membrane filtration system in the cleaning mode comprises activating an indicator to indicate a replacement of the filter in response to the normalized water permeability value of the filter being less than a predetermined percentage of the predetermined base value of the filter.

9. The method as claimed in claim 7 , comprising operating the membrane filtration system in the normal filtration mode in response to the normalized water permeability value of the filter being greater than or equal to a predetermined percentage of the predetermined base value of the filter.

10. The method as claimed in claim 9 , wherein operating the membrane filtration system in the normal filtration mode comprises resetting the first predetermined flux rate to a second predetermined flux rate less than the first predetermined flux rate.

11. The method as claimed in claim 1 , comprising storing, by the control unit, a unique identifier representative of operational information of the filter.

Assignments (2)
CHANGE OF NAME Recorded Dec 16, 2020
From: GE HEALTHCARE BIO-SCIENCES AB
To: CYTIVA SWEDEN AB
Reel/Frame 054772/0864 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 15, 2020
From: MAIYA, NITYANANDA; HINDUPUR, SAMEERA SIMHA; SELVARAJ, SHIVAKUMAR; SAHEBAGOUDA, ALAGUR; ARAVIND, DEEPAK; LUNDSTRÖM, FREDRIK OSKAR
To: GE HEALTHCARE BIO-SCIENCES AB
Reel/Frame 054647/0674 →
Priority Claims (1)
IN 201841023145 · Jun 21, 2018 · national
Continuity (1)
Related Publication 20210260530A1 · Aug 26, 2021