Granted Patent B2

US 12,458,785 · App. 17/274,521 · Granted Nov 4, 2025

Inventors: Michael Kulik (Mühlheim-Kärlich, DE); Thorsten Fehr (Andernach, DE); Stefan Erlhofer (Kempenich, DE); Sebastian Scherr (Neuhäusel, DE); Sebastian Dommasch (Mühlheim-Kärlich, DE)

Assignee: LTS Lohmann Therapie-Systeme AG

A61M37/0015A61M2037/0053B29C39/42B29C2045/0094B29C2045/1745

Abstract

Claims (29)

1 . A device for manufacturing microstructures comprising:

at least one permeable gas-transmissible template;

a vacuum chamber connected to the at least one permeable gas-transmissible template, wherein the vacuum chamber is configured such that the vacuum chamber at least temporarily maintains by itself an externally generated vacuum, and wherein the vacuum chamber comprises at least one vacuum chamber opening for connecting to a pump for generating a vacuum in the vacuum chamber; and

at least one self-closing valve for closing the at least one vacuum chamber opening such that an existing pressure ratio inside the vacuum chamber is maintained,

wherein the at least one permeable gas-transmissible template comprises at least one conical recess for manufacturing the microstructures,

wherein the pump is connected to the at least one permeable gas-transmissible template and the vacuum chamber such that the combination of the pump and the vacuum chamber generates the vacuum, and

wherein the vacuum is applied to at least one side of the at least one permeable gas-transmissible template.

2 . The device according to claim 1 , further comprising a coupling device for selectively coupling the vacuum chamber to the at least one permeable gas-transmissible template.

3 . The device according to claim 1 , wherein the valve is an elastic closure.

4 . The device according to claim 3 , further comprising a mold connected to the at least one permeable gas-transmissible template, wherein the mold comprises a flange for connecting to the vacuum chamber.

5 . The device according to claim 3 , further comprising a connecting element for providing a screwed connection between a mold and the vacuum chamber, wherein the mold is connected to the at least one permeable gas-transmissible template.

6 . The device according to claim 3 , wherein the closure is self-sealing after having been pierced.

7 . The device according to claim 1 , further comprising a mold integrally formed with the at least one permeable gas-transmissible template.

8 . The device according to claim 1 , further comprising a mold connected to the at least one permeable gas-transmissible template, wherein the at least one permeable gas-transmissible template and/or the mold comprises a plastic material.

9 . The device according to claim 1 , wherein the vacuum chamber comprises a flange and/or a thread.

10 . The device according to claim 9 , wherein a connecting element comprises a cap nut which is adapted to be placed over a mold such that the mold is screw-connected to the vacuum chamber, wherein the mold is connected to the at least one permeable gas-transmissible template.

11 . The device according to claim 1 , further comprising a gas-transmissible support element adapted to planarly abut on the at least one permeable gas-transmissible template for supporting the at least one permeable gas-transmissible template.

12 . The device according to claim 1 , wherein the vacuum is applied to at least one opposite side of at least one conical recess of the at least one permeable gas-transmissible template.

13 . The device according to claim 1 , further comprising a coupling device for selectively coupling the vacuum chamber to the at least one permeable gas-transmissible template via the vacuum chamber opening.

14 . A handling unit for manufacturing microstructures comprising a device for manufacturing microstructures according to claim 1 , wherein the handling unit serves as a carrier element for the microstructure to be manufactured during the entire manufacturing process.

15 . A method for filling a permeable gas-transmissible template according to claim 1 , wherein the permeable gas-transmissible template includes at least one recess for manufacturing microstructures, the method comprising the steps of:

feeding at least one liquid substance to be filled in to the permeable gas-transmissible template; and

generating a vacuum on at least one side of the permeable gas-transmissible template in at least opposite the at least one recess of the template,

wherein the step of generating the vacuum is performed before, after and/or during the step of feeding the substance to the template.

16 . The method according to claim 15 , further comprising:

evacuating a vacuum chamber connected to the permeable gas-transmissible template via a connection to the interior of the vacuum chamber for generating the vacuum.

17 . The method according to claim 16 , further comprising selectively coupling a vacuum-generating device to the permeable gas-transmissible template for generating the vacuum.

18 . The method according to claim 16 , further comprising penetrating an elastic valve of the vacuum chamber for creating the connection to the interior of the vacuum chamber.

19 . The method according to claim 15 , further comprising filling the vacuum chamber via a connection to an interior of the vacuum chamber for generating an atmospheric pressure or a positive pressure.

Assignments (1)

Priority Claims (1)

Continuity (1)

References Cited (28)