Slit-scanning fundus imager enhancements
View Patent ↗A scan imaging system has a scanning component that receives light from a light source, and creates a scanning beam that is directed by an optic train to a sample to be imaged. A camera captures light returning from the sample to construct an image. Reflexes on a target lens within the optic train are prevented by one or more light blocks. A first light block, imaged to the target lens, is positioned in alight path from the light source to the scanning component to create a first moving dark zone on the target lens through which the scanning beam from the scanning component to the sample may not pass. A second light block, also imaged to the target lens, is positioned in alight path from the sample to the collector to create a second moving dark zone on the target lens through which light returning from the sample may not pass. The moving dark zones maintain the scanning beam separate from the returning light on the target lens.
1. A scan imaging system comprising:
a radiation source;
a scanning component that receives radiation from the radiation source, and defines a scanning beam of radiation;
optics that direct the scanning beam of radiation to a sample to be imaged, the optics including a target optic element on which the scanning beam of radiation is scanned;
a radiation-blocking component positioned to partially block radiation output from the radiation source and to limit the radiation received by the scanning component, the radiation-blocking component being at a conjugate plane of the target optic element and creating a moving non-radiation zone on the target optic element through which the scanning beam of radiation may not pass, a portion of the scanning beam outside the moving non-radiation zone being scanned across the sample creating a moving region of illumination on the sample; and
a collector for collecting returning radiation from the moving region of illumination.
2. The scan imaging system of claim 1 , wherein the radiation-blocking component is positioned along a radiation path from the radiation source to the scanning component.
3. The scan imaging system of claim 1 , further comprising:
a collector-blocking component positioned to partially block radiation returning from the moving region of illumination, the collector-blocking component being at a conjugate plane of the target optic element and creating a moving non-collection zone on the target optic through which radiation returning from the moving region of illumination may not pass.
4. The scan imaging system of claim 3 , wherein the moving non-radiation zone moves in conjunction with, and at least partially overlaps, the moving non-collection zone on the target optic.
5. The scan imaging system of claim 3 , wherein the moving non-radiation zone moves in conjunction with, and abuts, the moving non-collection zone on the target optic.
6. The scan imaging system of claim 3 , wherein:
the scan imaging system has a first operating mode in which the radiation-blocking component is positioned to partially block radiation output from the radiation source and the collector-blocking component is positioned to partially block radiation returning from the moving region of illumination; and
the scan imaging system has a second operating mode in which the radiation-blocking component is positioned to not obstruct radiation output from the radiation source and the collector-blocking component is positioned to not obstruct radiation returning from the moving region of illumination.
7. The scan imaging system of claim 6 wherein:
the sample to be imaged is an eye;
the first operating mode corresponds to non-myopic eyes; and
the second operating mode correspond to myopic eyes of greater than a predefined diopter value.
8. The scan imaging system of claim 3 , further comprising:
a focus-adjustment mechanism that brings the sample into focus on the collector; wherein:
focusing the sample onto the collector causes the conjugate plane of the target optic element to move; and
the collector-blocking component moves in conjunction with the conjugate plane of the target optic element to remain on the conjugate plane of the target optic element.
9. The scan imaging system of claim 8 , wherein:
the position of the radiation-blocking component remains static irrespective of movement of the conjugate plane of the target optic element due to focusing of the sample onto the collector.
10. The scan imaging system of claim 3 , further comprising:
focus-adjusting optics that bring the sample into focus on the collector, the focus-adjusting optics being between the collector-blocking component and the collector;
wherein:
the relative positions all optics along a radiation returning path from the target optic element to the collector-blocking component are fixed; and
the collector-blocking component remains static and at the conjugate plane of the target optic element while the focus-adjusting optics focus the sample onto the collector.
11. The scan imaging system of claim 3 , wherein the radiation-blocking component is coplanar with the collector-blocking component.
12. The scan imaging system of claim 11 , further comprising:
an illumination aperture on a conjugate plane of a surface of the sample to be imaged, the illumination aperture being between the illumination source and the radiation-blocking component;
a collection aperture at a conjugate plane of the surface of the sample to be imaged, the collection aperture being between the collector and the collector-blocking component;
wherein the illumination aperture is coplanar with the collection aperture.
13. The scan imaging system of claim 12 , further comprising:
a splitting region substantially imaged to a position immediately preceding the scanning component in a radiation path from the radiation source to the scanning component, the splitting region separating the scanning beam of radiation at the sample from radiation returning from the sample, the splitting region having a first sample-opening through which the scanning beam of radiation passes and a second sample-opening through which radiation returning from the sample passes, the first sample-opening and second sample-opening being coplanar;
a dual lens embodied by two coplanar lenses molded as a single optic component, the dual lens including a first sub-lens aligned with the first sample-opening and a second sub-lens aligned to the second sample-opening;
a structural support maintaining alignment between the first sample-opening, the first sub-lens, the radiation-blocking component, and the illumination aperture, and maintaining alignment between the second sample-opening, the second sub-lens, the collector-blocking component, and the collector aperture.
14. The scan imaging system of claim 1 , wherein:
the sample to be imaged is an eye having a pupil and a fundus;
the scanning beam of radiation enters the eye through the pupil and creates the moving region of illumination on the fundus; and
radiation returning from the moving region of illumination exits the eye through the pupil;
the system further comprising:
radiation apertures positioned in front of the radiation source, the radiation apertures being imaged substantially to the fundus;
pupil splitting optics imaged substantially to the pupil of the eye, the pupil splitting optics separating the scanning beam of radiation entering the eye from the returning radiation exiting the eye, the pupil splitting optics including a pupil-aperture imaged substantially to the pupil;
wherein the radiation-blocking component is positioned between the pupil-aperture and the radiation aperture.
15. The scan imaging system of claim 1 , wherein the target optic element is a system lens positioned in a radiation path from the scanning component to the sample to be imaged.
16. The scan imaging system of claim 15 , wherein the system lens is closest to the sample on the radiation path from the scanning component to the sample.
17. The scan imaging system of claim 1 , wherein the radiation source is one of a laser source and an incoherent radiation source.
18. The scan imaging system of claim 1 , wherein the radiation output from the radiation source is a substantially rectangular beam of radiation.
19. The scan imaging system of claim 18 , wherein the rectangular beam of radiation has a length dimension and a variable width dimension substantially perpendicular to the length dimension.
20. The scan imaging system of claim 1 , wherein the scan imaging system is one of a point-scanning imager and a line scanning imager.
21. The scan imaging system of claim 1 , wherein the scan imaging system is one of a scan-no-descan system, a scan-descan system, and a scan-descan-rescan system.
22. The scan imaging system of claim 1 , further including a spherical mirror to counter field curvature aberrations of one or more lenses of the scan imaging system.
23. The scan imaging system of claim 22 , wherein the radius of curvature of the spherical mirror is adjusted along the plane of reflection of the incident beam to reduce or eliminate an astigmatism of the spherical mirror.
24. The scan imaging system of claim 1 , further including:
a first spherical mirror; and
a second spherical mirror positioned to receive a reflected signal from the first spherical mirror and having a plane of reflection orthogonal to a plane of reflection at the first spherical mirror to counter an astigmatism of the first spherical mirror.
25. The scan imaging system of claim 1 , further comprising cross polarizers, including a first polarizer positioned in the optical path from the radiation source to the sample, and a second polarizer in an orthogonal state relative to the first polarizer and positioned in the optical path from the sample to the collector.