IP Library Granted Patent US 12,070,037
Granted Patent B2
US 12,070,037 · App. 17/279,679 · Granted Aug 27, 2024

Methods and compositions for bioprotection of potatoes from

Inventors: Fazli Mabood (Centennial, CO); Aaron L. Waltz (Centennial, CO); Margaret Ann Bywater-Ekegard (Centennial, CO); Donald Lawrence Smith (Montreal, CA)
Assignee: The Royal Institution for the Advancement of Learning/McGill University
A01N63/22C12N1/20C12N2500/30
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 12,070,037
App. No.
17/279,679
Granted
Aug 27, 2024
Kind
B2
Abstract

The present invention relates to compositions having antimicrobial activity against Streptomyces scabies . Further provided herein are methods of making and using the antimicrobial compositions to protect and treat potatoes from Streptomyces scabies infections.

Claims (24)

1. A method of controlling, suppressing and/or preventing infection from Streptomyces scabies in potatoes, comprising the step of:

providing an antimicrobial composition comprising at least one of Bacillus pumilus strain, a culture medium inoculated with Bacillus pumilus , a purified extract of Bacillus pumilus or at least one metabolite of Bacillus pumilus , wherein said antimicrobial composition comprises Micrococcin P1; and

applying an effective amount of said antimicrobial composition to at least one of potatoes tubers, potatoes roots, potatoes stems, potatoes leaves, and potatoes propagules.

2. The method of claim 1 , wherein the Micrococcin P1 is produced by the Bacillus pumilus.

3. The method of claim 1 , wherein the composition further comprises a cell free supernatant of a microorganism mixture comprising Lactobacillus paracasei, Lactobacillus helveticus, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactococcus lactis, Bacillus amyloliquefaciens, Aspergillus oryzae, Saccharomyces cerevisiae, Candida utilis , and Rhodopseudomonas palustris , or a mixture thereof.

4. The method of claim 1 , wherein said method provides for bioprotection of potatoes against Streptomyces scabies , and wherein said bioprotection is determined by comparing damages of potatoes contacted or not with said antimicrobial composition.

5. The method of claim 1 , wherein said method provides for at least one of: enhancing resistance against Streptomyces scabies , reduction damage caused by Streptomyces scabies , enhancing plant antimicrobial response against Streptomyces scabies , increasing plant antinematocidal activity, and reducing pathological symptoms or lesions resulting from actions of Streptomyces scabies , and increasing tuber yield.

6. The method of claim 1 , wherein said Bacillus pumilus strain comprises a 16S rRNA having at least 95% identity with SEQ ID NO: 4.

7. The method of claim 1 , wherein said antimicrobial composition further comprises at least one strain of Bacillus subtilis , a culture medium inoculated with Bacillus subtilis , a cell-free extract of Bacillus subtilis or at least one metabolite of Bacillus subtilis.

8. The method of claim 1 , wherein said antimicrobial composition further comprises at least one of an herbicide, an insecticide, a fungicide and a nutrient.

9. The method of claim 1 , wherein the purified extract of Bacillus pumilus comprises a cell-free supernatant of Bacillus pumilus.

10. A composition effective in bioprotection of potatoes from Streptomyces scabies , comprising:

an effective amount of Micrococcin P1; and

an agriculturally acceptable carrier,

wherein said composition is formulated for application to at least one of potatoes tubers, potatoes roots, potatoes stems, potatoes leaves and potatoes propagules; and

wherein said Micrococcin P1 is effective in controlling, suppressing and/or preventing infection from Streptomyces scabies.

11. The composition of claim 10 , wherein the Micrococcin P1 is produced by Bacillus pumilus.

12. The composition of claim 10 , further comprising Bacillus subtilus.

13. The composition of claim 10 , further comprising a filtered fraction of a microbial culture comprising Lactobacillus paracasei, Lactobacillus helveticus, Lactobacillus plantarum, Lactobacillus rhamnosus, Lactococcus lactis, Bacillus amyololiquefaciens, Aspergillus oryzae, Saccharomyces cerevisiae, Candida utilis , and Rhodopseudomonas palustris , or a mixture thereof.

14. The composition of claim 10 , wherein said Bacillus pumilus strain comprises a 16S rRNA having at least 95% identity with SEQ ID NO: 4.

15. The composition of claim 10 , further comprising at least one strain of Bacillus subtilis , a culture medium inoculated with Bacillus subtilis , a cell-free extract of Bacillus subtilis or at least one metabolite of Bacillus subtilis.

16. A method of protecting potatoes from Streptomyces scabies , comprising the step of:

applying an effective amount of the composition of claim 10 to a soil where potato plants are growing,

wherein the effective amount is sufficient for bioprotection of the potatoes from Streptomyces scabies.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2021
From: MABOOD, FAZLI; WALTZ, AARON L; BYWATER-EKEGARD, MARGARET A
To: CONCENTRIC AG CORPORATION
Reel/Frame 057441/0850 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2021
From: SMITH, DONALD L
To: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
Reel/Frame 057444/0198 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2021
From: CONCENTRIC AG CORPORATION
To: THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIVERSITY
Reel/Frame 057444/0203 →
Continuity (3)
Provisional Application 62737747 · Sep 27, 2018
Provisional Application 62744101 · Oct 10, 2018
Related Publication 20210392902A1 · Dec 23, 2021