Product packaging with heat sealable barrier material
A package that is suitable for packaging an article for collecting or administering a pharmaceutical active substance is disclosed. The package includes a first packaging component that includes a product-contacting sealant layer that includes a first ethylene vinyl alcohol copolymer. The package includes a second packaging component that includes a product-contacting sealant layer that includes a second ethylene vinyl alcohol copolymer. The ethylene content of the second ethylene vinyl alcohol copolymer is equal to or less than about 38 percent and the ethylene content of the first ethylene vinyl alcohol copolymer is greater than the ethylene content of the second ethylene vinyl alcohol copolymer.
1. A package comprising:
a first packaging component comprising a product-contacting sealant layer comprising a first ethylene vinyl alcohol copolymer; and
a second packaging component comprising a product-contacting sealant layer comprising a second ethylene vinyl alcohol copolymer;
wherein the ethylene content of the second ethylene vinyl alcohol copolymer is equal to or less than 38 percent, and wherein the ethylene content of the first ethylene vinyl alcohol copolymer is greater than the ethylene content of the second ethylene vinyl alcohol copolymer, wherein the product-contacting sealant layer of the first packaging component is an interior surface layer, and wherein the product-contacting sealant layer of the second packaging component is an interior surface layer.
2. A package according to claim 1 , wherein the ethylene content of the second ethylene vinyl alcohol copolymer is 38 percent.
3. A package according to claim 2 , wherein the ethylene content of the first ethylene vinyl alcohol copolymer is greater than 38 percent.
4. A package according to claim 1 , wherein the first packaging component comprises at least 95 wt. percent of the first ethylene vinyl alcohol copolymer and the second packaging component comprises at least 95 wt. percent of the second ethylene vinyl alcohol copolymer.
5. A package according to claim 1 , wherein the first packaging component consists essentially of the first ethylene vinyl alcohol copolymer and the second packaging component consists essentially of the second ethylene vinyl alcohol copolymer.
6. A package according to claim 1 , wherein the first and second ethylene vinyl alcohol copolymers are heat sealed to each other under conditions of 163 degrees Celsius to 193 degrees Celsius, 1 second dwell time and 0.2 MPa pressure and comprise a peak heat seal strength of at least 525 Newton/m (3 pounds-force/inch) when tested according to ASTM F88.
7. A package according to claim 1 , further comprising a water or moisture transmission rate (WVTR) 0.1 g/m 2 /24 hours at 38 degrees Celsius and 90 percent relative humidity according to ASTM F1249.
8. A package according to claim 1 , further comprising an oxygen transmission rate (OTR) of equal to or less than 0.25 cc/m 2 /24 hours at 1 atmosphere and 23 degrees Celsius and 0 percent relative humidity according to ASTM F1927.
9. A package according to claim 1 , wherein the package is in the form of a pouch, sachet, or thermoformed blister and/or tray and lid.
10. A package according to claim 1 , further comprising a pharmaceutical active agent that is hermetically sealed within the package, wherein the pharmaceutical active agent is selected from the group consisting of nicotine, tetrahydrocannabinol (THC), fentanyl, acetylfentanyl, lidocaine, clonidine, ethinyl estradiol, estradiol, oxybutynin, buprenorphine, granisetron, methylphenidate, and scopolamine.
11. A package according to claim 1 , further comprising a RED value of 1.0 or greater.
12. A packaged product comprising the package according to claim 1 , wherein a product is located between the first packaging component and the second packaging component, and wherein the product comprises a pharmaceutical active agent.
13. The packaged product according to claim 12 , wherein the pharmaceutical active agent comprises nicotine, tetrahydrocannabinol (THC), acetylfentanyl, lidocaine, or a combination thereof.
14. A package comprising:
a first packaging component comprising a product-contacting sealant layer comprising a first ethylene vinyl alcohol copolymer and an aluminum foil layer; and
a second packaging component comprising a product-contacting sealant layer comprising a second ethylene vinyl alcohol copolymer and a barrier layer comprising ethylene vinyl acetate (EVA);
wherein the first ethylene vinyl alcohol copolymer has an ethylene content of 48 mol percent, wherein the second ethylene vinyl alcohol copolymer has an ethylene content of 38 mol percent, and wherein the first and second ethylene vinyl alcohol copolymers are heat sealed to each other, wherein the product-contacting sealant layer of the first packaging component is an interior surface layer, and wherein the product-contacting sealant layer of the second packaging component is an interior surface layer.
15. A package according to claim 2 , wherein the first packaging component comprises at least 95 wt. percent of the first ethylene vinyl alcohol copolymer and the second packaging component comprises at least 95 wt. percent of the second ethylene vinyl alcohol copolymer.
16. A package according to claim 3 , wherein the first packaging component comprises at least 95 wt. percent of the first ethylene vinyl alcohol copolymer and the second packaging component comprises at least 95 wt. percent of the second ethylene vinyl alcohol copolymer.
17. A package according to claim 2 , wherein the first packaging component consists essentially of the first ethylene vinyl alcohol copolymer and the second packaging component consists essentially of the second ethylene vinyl alcohol copolymer.
18. A package according to claim 3 , wherein the first packaging component consists essentially of the first ethylene vinyl alcohol copolymer and the second packaging component consists essentially of the second ethylene vinyl alcohol copolymer.