IP Library Granted Patent US 11,603,541
Granted Patent B2
US 11,603,541 · App. 17/313,801 · Granted Mar 14, 2023

Compositions and method of making a complex able to increase production of a cetuximab-like protein (CLP) in a target cell

Inventor: Bradley G. Thompson (Calgary, CA)
Assignee: KINASE PHARMA INC.
C12N15/86C07K16/2863A61K48/00C07K2317/24C12N2330/50C12N2750/14143
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Quick Facts
Patent No.
US 11,603,541
App. No.
17/313,801
Granted
Mar 14, 2023
Kind
B2
Abstract

The present disclosure relates to one or more agents, therapies, treatments, and methods of use of the agents and/or therapies and/or treatments for increasing production of a Cetuximab-like protein (CLP) by a subject that is administered the agent, therapy or treatment. Embodiments of the present disclosure can be used as a therapy or a treatment for a subject that has a condition that may benefit from reducing the DNA synthesis of genes that regulate cellular growth and proliferation.

Claims (4)

1. A composition that comprises a nucleotide sequence according to SEQ ID No. 9 that can be expressed in a target cell.

2. A pharmaceutical composition comprising a nucleotide sequence according to SEQ ID No. 9 and one or more pharmaceutically acceptable carriers and/or one or more excipients.

3. A method of making an agent/target cell complex, the method comprising a step of administering a nucleotide sequence according to SEQ ID No. 9 to a target cell for forming the agent/target cell complex, wherein the agent/target cell complex causes the target cell to increase production of a Cetuximab-like protein (CLP).

4. The method of claim 3 , wherein the target cell is one or more of an adrenal gland cell; a bile duct cell; a chondrocyte; a cochlear cell; a corneal cell; an endocardium cell; an endometrial cell; an endothelial cell; an epithelial cell; a fibroblast; a hair follicle cell; a hepatocyte; a lymph node cell; a mucosal cell; a myocyte; a neuron; a glomeruli cell; an optic nerve cell; an osteoblast; an ovarian tissue cell; a pancreatic islet beta cell; a pericardium cell; a platelet; a red blood cell (RBC); a retinal cell; a scleral cell; a Schwann cell; a T cell; a testicular tissue cell; a thyroid gland cell; a uveal cell; a tumor cell, and combinations thereof.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 6, 2021
From: THOMPSON, BRADLEY G.
To: KINASE PHARMA INC.
Reel/Frame 056765/0406 →
Continuity (1)
Related Publication 20220356489A1 · Nov 10, 2022
Cited By (1)
US 12,263,232