IP Library Granted Patent US 11,484,413
Granted Patent B1
US 11,484,413 · App. 17/314,357 · Granted Nov 1, 2022

Sheet based triply periodic minimal surface implants for promoting osseointegration and methods for producing same

Inventors: Andrew Todd Miller (Durham, NC); Matthew Rexrode (Durham, NC); Cambre Kelly (Durham, NC); Ken Gall (Durham, NC)
Assignees: RESTOR3D, INC.; DUKE UNIVERSITY
A61F2/3094A61F2/4455A61F2002/30736A61F2002/30784A61F2002/30985A61F2310/00023
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Quick Facts
Patent No.
US 11,484,413
App. No.
17/314,357
Granted
Nov 1, 2022
Kind
B1
Abstract

Provided herein are implants and methods for producing implants. In at least one embodiment, the implants include sheet-based, triply periodic, minimal surface (TPMS) portions. According to one embodiment, the TPMS portions include a gyroid architecture that provides for improved osseointegration and mechanical performance over previous implants due to novel ratios of porosity to compressive strength, among other features. In one or more embodiments, the gyroid architecture is organized into unit cells that demonstrate anisotropic mechanical performance along an insertion direction. In various embodiments, the present methods include novel selective laser melting (SLM) techniques for forming the TPMS portions of implants in a manner that reduces defect formation, thereby improving compressive performance and other implant properties.

Claims (30)

1. A 3D-printed implant comprising:

a top point and a bottom point;

a frame comprising:

an interior portion, wherein the interior portion defines a void area; and

a sheet-based triply periodic minimal surface (TPMS) portion integrally formed with the frame via SLM 3D printing extending from the top point through the void area of the frame to the bottom point, the TPMS portion comprising:

a wall density greater than 99%; and

a porosity of about 50-90%.

2. The 3D-printed implant of claim 1 , wherein the TPMS portion is free of nodes.

3. The 3D-printed implant of claim 1 , wherein the interior portion defines a second void area free of TPMS structures.

4. The 3D-printed implant of claim 1 , wherein the 3D-printed implant is anisotropic in an insertion direction.

5. The 3D-printed implant of claim 1 , wherein the 3D-printed implant is a spinal cage.

6. The 3D-printed implant of claim 1 , wherein the 3D-printed implant is an osteotomy wedge.

7. The 3D-printed implant of claim 1 , wherein the TPMS portion comprises a gyroid architecture.

8. A 3D-printed implant comprising:

an area between a top portion and a bottom portion, the area comprising at least one sheet based triply periodic minimal surface (TPMS) portion comprising:

a wall density greater than 99%; and

a porosity of about 50-90%.

9. The 3D-printed implant of claim 8 , wherein:

the top portion and the bottom portion define an interior portion; and

the interior portion defines at least one void area.

10. The 3D-printed implant of claim 8 , wherein the at least one TPMS portion comprises a gyroid architecture.

11. The 3D-printed implant of claim 8 , wherein the at least one TPMS portion is free of nodes.

12. The 3D-printed implant of claim 8 , further comprising one or more teeth extending from the top portion or the bottom portion.

13. The 3D-printed implant of claim 8 , wherein the 3D-printed implant is anisotropic in an insertion direction.

14. The 3D-printed implant of claim 8 , wherein the 3D-printed implant is a spinal cage.

15. The 3D-printed implant of claim 8 , wherein the 3D-printed implant is an osteotomy wedge.

16. The 3D-printed implant of claim 8 , wherein the at least one TPMS portion comprises titanium.

17. The 3D-printed implant of claim 8 , wherein the at least one TPMS portion comprises cobalt chromium.

18. A 3D-printed implant comprising:

a volume between a top portion and a bottom portion, the volume comprising at least one sheet based triply periodic minimal surface (TPMS) portion comprising a wall density greater than 99%.

Assignments (5)
SECURITY INTEREST Recorded Jun 7, 2024
From: RESTOR3D, INC.; CONFORMIS, INC.; IMATX, INC.
To: TRINITY CAPITAL INC., AS ADMINISTRATIVE AGENT
Reel/Frame 067679/0713 →
RELEASE OF SECURITY INTEREST Recorded Jan 9, 2023
From: WELLS FARGO BANK, NATIONAL ASSOCIATION
To: SEASPINE HOLDINGS CORPORATION; SEASPINE ORTHOPEDICS CORPORATION; SEASPINE, INC.; ISOTIS, INC.; SEASPINE SALES LLC; ISOTIS ORTHOBIOLOGICS, INC.; THEKEN SPINE, LLC; SEASPINE ORTHOPEDICS INTERMEDIATECO, INC.; 7D SURGICAL USA INC.
Reel/Frame 062336/0593 →
SECOND AMENDMENT TO PATENT SECURITY AGREEMENT Recorded Jul 18, 2022
From: SEASPINE HOLDINGS CORPORATION; SEASPINE ORTHOPEDICS CORPORATION; SEASPINE, INC.; ISOTIS, INC.; SEASPINE SALES LLC; ISOTIS ORTHOBIOLOGICS, INC.; THEKEN SPINE, LLC; SEASPINE ORTHOPEDICS INTERMEDIATECO, INC.; 7D SURGICAL USA INC.
To: WELLS FARGO BANK, NATIONAL ASSOCIATION, AS AGENT
Reel/Frame 060715/0395 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 28, 2021
From: GALL, KEN; KELLY, CAMBRE
To: DUKE UNIVERSITY
Reel/Frame 056685/0856 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 12, 2021
From: MILLER, ANDREW TODD; REXRODE, MATTHEW
To: RESTOR3D, INC.
Reel/Frame 056212/0381 →
Continuity (2)
Continuation 16991638 · Aug 12, 2020
Continuation 16737341 · Jan 8, 2020
Cited By (2)
US 12,591,216 US 12,605,251