Carbohydrate-binding small molecules with antiviral activity
Compounds with anti-viral properties are provided that are based on the following structures: A variety of heteroaromatic groups have been found to be biologically active against viral infections. In some embodiments, a dimeric compound is provided with each monomer linked by a repeating glycol linking group.
1. A method for treating a human for a viral infection, the method comprising:
administering a synthetic carbohydrate receptor (SCR) to a human, wherein the SCR has a structure of:
wherein Het is 2-pyrrole (SCR004), 2-furan (SCR005) or 2-thiophene (SCR006).
2. The method as recited in claim 1 , wherein Het is 2-pyrrole.
3. The method as recited in claim 1 , wherein Het is 2-furan.
4. A method for treating a human for a viral infection, the method comprising:
administering a synthetic carbohydrate receptor (SCR) to a human, wherein the SCR has a structure of:
wherein Het is 2-thiophene.