Compositions and methods of treating cognitive impairment
The present invention relates generally method of treating or alleviating cognitive impairment by administering an abuse-deterrent formulation containing dextroamphetamine sulfate.
1. A method of treating or alleviating a symptom of cognitive impairment comprising administering to a subject whom has had a COVID-19 infection an abuse-deterrent formulation comprising a unit dose of about 10 mg to about 50 mg dextroamphetamine or a pharmaceutically acceptable salt thereof, poloxamer 124, gellan gum, and polyoxyl stearate.
2. The method of claim 1 , wherein the ratio of poloxamer 124:gellan gum:polyoxyl stearate is about 40:30:30.
3. The method of claim 1 , wherein the formulation is administered once a day.
4. The method of claim 1 , wherein the formulation is in the form of a capsule.
5. The method of claim 4 , wherein the capsule is a hard shell capsule.
6. The method of claim 1 , wherein the symptom of cognitive impairment is problems in concentration in studies and/or work; exhibiting reluctance or difficulty in acquiring new skills; finding multitasking jobs daunting; confusion; short-term memory loss; not able to give attention to a particular thing for a long time; slow in completing usual tasks; difficulty in recalling a conversation or finding the right word to form a sentence; forgetfulness with image or list of words; fatigue, mild depression, or anxiety.
7. The method of claim 1 , wherein the subject has received mechanical ventilation.