IP Library › Granted Patent US 11,900,620
Granted Patent B2
US 11,900,620 · App. 17/324,633 · Granted Feb 13, 2024

Method and system for registering images containing anatomical structures

Inventors: Florent Lalys (Rennes, FR); Mathieu Colleaux (Rennes, FR); Vincent Gratsac (Thorigné-Fouillard, FR)
Assignee: THERENVA
G06T7/33G06F18/2431G06T2200/04G06T2207/10064G06T2207/10081G06T2207/10088G06T2207/20084G06T2207/20221G06T2207/30101G06V2201/03
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Quick Facts
Patent No.
US 11,900,620
App. No.
17/324,633
Granted
Feb 13, 2024
Kind
B2
Abstract

A method for registration between a first three-dimensional image acquired according to a first acquisition mode, and including anatomical structures of a patient, and a second two-dimensional image, acquired according to a second acquisition mode by a rotatable and translatable device, the second image including a portion of the anatomical structures of the patient. The registration implements a rigid spatial transformation defined by rotation and translation parameters. The method includes automatically detecting the anatomical structures in the two-dimensional image by applying a first detection neural network trained on a generic database; estimating, from the anatomical structures automatically detected in the second two-dimensional image, by applying at least one classification neural network trained beforehand on a generic database, the rotation and translation parameters of the rigid spatial transformation; and 3D/2D iconic registration between the first three-dimensional image and the second two-dimensional image starting from an initialization with the rigid spatial transformation.

Claims (33)

1. A method for registration between a first three-dimensional image acquired according to a first acquisition mode, and comprising anatomical structures of a patient, and a second two-dimensional image, acquired according to a second acquisition mode by an image acquisition device mounted on a scoping arch movable in rotation and in translation, the second image comprising a portion of the anatomical structures of said patient, the registration implementing a rigid spatial transformation defined by rotation and translation parameters,

the method being implemented by a processor of a programmable electronic device and comprising:

automatic detection of the anatomical structures in the two-dimensional image by application of a first detection neural network trained on a generic database,

estimation, from the anatomical structures automatically detected in said second two-dimensional image, by application of at least one classification neural network trained beforehand on a generic database, of the rotation and translation parameters of said rigid spatial transformation, said estimation including:

a first estimation, from said anatomical structures automatically detected in said second two-dimensional image, by application of said at least one classification neural network, of a first angle of rotation and of a second angle of rotation of said rigid spatial transformation, characterizing the position of the scoping arch, and

a second estimation of translational parameters, of a third angle of rotation and of a zoom factor of said rigid spatial transformation, the second estimation using a result of the first estimation, and

3D/2D iconic registration between the first three-dimensional image and the second two-dimensional image starting from an initialization with said rigid spatial transformation.

2. The method according to claim 1 , wherein the anatomical structures are classified into a plurality of predetermined anatomical structure categories, and wherein the estimation of the parameters of the rigid transformation includes the implementation of a second classification neural network per anatomical structure category to obtain transformation parameters estimated per anatomical structure category.

3. The method according to claim 1 , wherein a classification neural network is applied per anatomical structure category to obtain a first angle of rotation and a second angle of rotation estimated per anatomical structure category, the method further including a stitching of the first angles of rotation estimated per anatomical structure category to obtain said estimated first angle of rotation, and a stitching of the second angles of rotation estimated per anatomical structure category to obtain said estimated second parameter.

4. The method according to claim 3 , wherein each stitch consists of an average value calculation or of a median value calculation.

5. The method according to claim 1 , wherein the second estimation comprises:

a generation of a third two-dimensional image obtained from the first three-dimensional image by applying said first and second angles of rotation,

an automatic detection of anatomical structures on said third image, and

a pairing between the structures of said second and third two-dimensional images to obtain said translation parameters, the third angle of rotation and the zoom factor of said rigid spatial transformation.

6. The method according to claim 5 , wherein the detection of anatomical structures in said third two-dimensional image is performed by application of said first detection neural network.

7. The method according to claim 1 , wherein said anatomical structures are bone structures obtained on a second two-dimensional image acquired by fluoroscopy.

8. The method according to claim 1 , wherein said anatomical structures are vascular structures obtained on a second two-dimensional image acquired by angiography.

9. The method according to claim 1 , wherein the first three-dimensional image is acquired according to a first acquisition mode among tomography, MRI, 3D sonography or cone beam computed tomography.

10. A device for registration between a first three-dimensional image acquired according to a first acquisition mode, and comprising anatomical structures of a patient, and a second two-dimensional image, acquired according to a second acquisition mode by an image acquisition device mounted on a scoping arch movable in rotation and in translation, the second image comprising a portion of the anatomical structures of said patient, the registration implementing a rigid spatial transformation defined by rotation and translation parameters,

the device including a processor configured to implement:

automatic detection of the anatomical structures in the two-dimensional image by application of a first detection neural network trained on a generic database,

estimation, from the anatomical structures automatically detected in said second two-dimensional image, by application of at least one classification neural network trained beforehand on a generic database, of the rotation and translation parameters of said rigid spatial transformation, said estimation including:

a first estimation, from said anatomical structures automatically detected in said second two-dimensional image, by application of said at least one classification neural network, of a first angle of rotation and of a second angle of rotation of said rigid spatial transformation, characterizing the position of the scoping arch, and

a second estimation of translational parameters, of a third angle of rotation and of a zoom factor of said rigid spatial transformation, the second estimation using a result of the first estimation, and

3D/2D iconic registration between the first three-dimensional image and the second two-dimensional image starting from an initialization with said rigid spatial transformation.

11. A system for registration between a first three-dimensional image acquired according to a first acquisition mode, and comprising anatomical structures of a patient, and a second two-dimensional image, acquired according to a second acquisition mode, the system comprising:

an image acquisition device mounted on a scoping arch movable in rotation and in translation, configured to acquire the second two-dimensional image, the second two-dimensional image comprising a portion of the anatomical structures of said patient, and

a device for registration between the first three-dimensional image and the second two-dimensional image, the registration implementing a rigid spatial transformation defined by rotation and translation parameters, the device including a processor configured to implement:

automatic detection of the anatomical structures in the two-dimensional image by application of a first detection neural network trained on a generic database,

estimation, from the anatomical structures automatically detected in said second two-dimensional image, by application of at least one classification neural network trained beforehand on a generic database, of the rotation and translation parameters of said rigid spatial transformation, said estimation including:

a first estimation, from said anatomical structures automatically detected in said second two-dimensional image, by application of said at least one classification neural network, of a first angle of rotation and of a second angle of rotation of said rigid spatial transformation, characterizing the position of the scoping arch, and

a second estimation of translational parameters, of a third angle of rotation and of a zoom factor of said rigid spatial transformation, the second estimation using a result of the first estimation, and

3D/2D iconic registration between the first three-dimensional image and the second two-dimensional image starting from an initialization with said rigid spatial transformation.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 1, 2021
From: LALYS, FLORENT; COLLEAUX, MATHIEU; GRATSAC, VINCENT
To: THERENVA
Reel/Frame 056402/0550 →
Priority Claims (1)
FR 2005371 · May 20, 2020 · national
Continuity (1)
Related Publication 20210366135A1 · Nov 25, 2021
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