IP Library Granted Patent US 12,575,797
Granted Patent B2
US 12,575,797 · App. 17/344,342 · Granted Mar 17, 2026

Blood glucose disease management system

Inventors: Gregory A. Olsen (Lake Forest, CA); Sai Kong Frank Lee (Irvine, CA); Jesse Chen (Foothill Ranch, CA); Hung The Vo (Fountain Valley, CA); Kevin Hughes Pauley (Lake Forest, CA)
Assignee: Willow Laboratories, Inc.
A61B5/742A61B5/4839A61B5/7275A61B5/7405A61B5/7455A61B5/746
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Quick Facts
Patent No.
US 12,575,797
App. No.
17/344,342
Granted
Mar 17, 2026
Kind
B2
Abstract

The disease management system can determine a measurement of one or more physiological parameters and can determine a disease event based on the one or more measurements. Furthermore, the disease management system can determine a pose of an individual using a pose sensor. Based on an identification of a disease event and a determination that the pose of the individual corresponds to a first pose, the disease management system can cause at least one of an audible, visual, or vibratory alarm. Based on an identification of a disease event and a determination that the pose of the individual does not correspond to the first pose, the disease management system can cause administration of a medication to the individual.

Claims (71)

1 . A disease management system comprising:

a wearable device configured for placement on an individual's torso, the wearable device comprising:

a blood glucose sensor configured to measure blood glucose data;

a pose sensor configured to provide pose information of the individual;

a needle;

an actuator configured to administer glucagon to the individual; and

one or more processors in communication with the blood glucose sensor and the pose sensor and configured reduce a risk of the individual choking in response to administration of glucagon, the one or more processors programmed to:

determine a pose of the individual based at least in part on the pose information,

determine a blood glucose measurement based at least in part on the blood glucose data,

identify a hypoglycemic event of the individual based at least in part on the blood glucose measurement;

determine whether a status of the individual is a safe treatment status or an unsafe treatment status, wherein the safe treatment status is indicated by the detection of the hypoglycemic event and determination that the pose of the individual is a pose other than lying on their back, and wherein the unsafe treatment status is indicated by detection of the hypoglycemic event and determination that the pose of the individual is lying on their back;

cause, if the individual's status is the unsafe treatment status, at least one of an audible, visual, or vibratory alarm and revoke authorization for the actuator to administer glucagon, wherein the audible, visual, or vibratory alarm is indicative that the individual should reposition themself;

inject the needle into the individual, if the individual's status is the safe treatment status; and

administer, if the individual's status is the safe treatment status, the glucagon to the individual using the actuator via the needle.

2 . The disease management system of claim 1 , wherein the one or more processors are programmed to perform a calibration procedure, wherein performance of the calibration procedure calibrates the pose of the individual relative to a pose of the disease management system.

3 . The disease management system of claim 2 , wherein to perform the calibration procedure, the one or more processors are programmed to:

obtain a set of pose data from the pose sensor, wherein the set of pose data corresponds to a plurality of activities of the individual; and

calibrate the pose sensor based at least in part on the set of pose data.

4 . The disease management system of claim 3 , wherein the plurality of activities comprises standing, walking, running, sitting up, lying on back, lying on front, or lying on side.

5 . The disease management system of claim 2 , wherein to perform the calibration procedure, the one or more processors are programmed to:

obtain first pose information from the pose sensor, wherein the first pose information corresponds to a first activity of the individual;

obtain second pose information from the pose sensor, wherein the second pose information corresponds to a second activity of the individual; and

calibrate the pose sensor based at least in part on the first pose information and the first pose information.

6 . The disease management system of claim 5 , wherein the first activity correspond to standing and the second activity corresponds to walking in a straight line.

7 . The disease management system of claim 5 , wherein to obtain the first pose information, the one or more processors are programmed to:

communicate a first instruction indicating for the individual to perform the second activity,

determine that the individual is not moving, and

responsive to the determination that the individual is not moving, obtain the second pose information.

8 . The disease management system of claim 5 , wherein to obtain the second pose information, the one or more processors are programmed to:

communicate a second instruction indicating for the individual to perform the second activity,

determine that the individual is moving, and

responsive to the determination that the individual is moving, obtain the second pose information.

9 . The disease management system of claim 1 , wherein the one or more processors are programmed to confirm that the disease management system is coupled to the individual prior to causing administration of the glucagon to the individual.

10 . The disease management system of claim 1 , further comprising a sensor configured to measure conductance, wherein to determine confirm that the disease management system is coupled to the individual based at least on part on the measurement of the conductance.

11 . The disease management system of claim 1 , wherein the one or more processors are programmed to cause an alarm indicating to replace adhesive of the disease management system based at least in part on a determination that a conductance measurement does not satisfy a conductance threshold.

12 . The disease management system of claim 1 , wherein the one or more processors is programmed to determine a change in the individual's status from the unsafe treatment status to the safe treatment status in response to the audible, visual, or vibratory alarm and, restore authorization to administer glucagon to the actuator, and using the actuator, administer the glucagon to the individual while the individual's status is the safe treatment status.

13 . A disease management system comprising:

a blood glucose sensor configured to measure blood glucose data;

a pose sensor configured for placement on an individual's torso and to provide pose information of the individual;

a needle;

an actuator configured to administer glucagon to the individual; and

one or more processors in communication with the blood glucose sensor and the pose sensor and configured reduce a risk of the individual choking in response to administration of glucagon, the one or more processors programmed to:

determine a pose of the individual based at least in part on the pose information,

determine a blood glucose measurement based at least in part on the blood glucose data,

identify a hypoglycemic event of the individual based at least in part on the blood glucose measurement;

determine whether a status of the individual is a safe treatment status or an unsafe treatment status, wherein the safe treatment status is indicated by the detection of the hypoglycemic event and determination that the pose of the individual is lying on their back, and wherein the unsafe treatment status is indicated by detection of the hypoglycemic event and determination that the pose of the individual is a pose other than lying on their back;

cause, if the individual's status is the unsafe treatment status, at least one of an audible, visual, or vibratory alarm and revoke authorization for the actuator to administer glucagon, wherein the audible, visual, or vibratory alarm is indicative that the individual should reposition themself;

determine a change in the individual's status from the unsafe treatment status to the safe treatment status in response to the audible, visual, or vibratory alarm;

restore authorization to administer glucagon to the actuator in response to return to safe treatment status;

confirm that the disease management system is coupled to the individual prior to causing administration of the glucagon to the individual;

cause an alarm indicating to replace adhesive of the disease management system based at least in part on a determination that a conductance measurement does not satisfy a conductance threshold;

inject the needle into the individual while the individual's status is the safe treatment status; and

administer, while the individual's status is the safe treatment status, the glucagon to the individual using the actuator via the needle.

14 . The disease management system of claim 13 , wherein the one or more processors are programmed to perform a calibration procedure, wherein performance of the calibration procedure calibrates the pose of the individual relative to a pose of the disease management system.

15 . The disease management system of claim 14 , wherein to perform the calibration procedure, the one or more processors are programmed to:

obtain a set of pose data from the pose sensor, wherein the set of pose data corresponds to a plurality of activities of the individual; and

calibrate the pose sensor based at least in part on the set of pose data.

16 . The disease management system of claim 15 , wherein the plurality of activities comprises standing, walking, running, sitting up, lying on back, lying on front, or lying on side.

17 . The disease management system of claim 14 , wherein to perform the calibration procedure, the one or more processors are programmed to:

obtain first pose information from the pose sensor, wherein the first pose information corresponds to a first activity of the individual;

obtain second pose information from the pose sensor, wherein the second pose information corresponds to a second activity of the individual; and

calibrate the pose sensor based at least in part on the first pose information and the first pose information.

18 . The disease management system of claim 17 , wherein the first activity correspond to standing and the second activity corresponds to walking in a straight line.

19 . The disease management system of claim 17 , wherein to obtain the first pose information, the one or more processors are programmed to:

communicate a first instruction indicating for the individual to perform the second activity,

determine that the individual is not moving, and

responsive to the determination that the individual is not moving, obtain the second pose information.

20 . The disease management system of claim 17 , wherein to obtain the second pose information, the one or more processors are programmed to:

communicate a second instruction indicating for the individual to perform the second activity,

determine that the individual is moving, and

responsive to the determination that the individual is moving, obtain the second pose information.

Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 3, 2026
From: PAULEY, KEVIN HUGHES
To: MASIMO LABORATORIES
Reel/Frame 073679/0699 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 14, 2026
From: OLSEN, GREGORY A.; LEE, SAI KONG FRANK; CHEN, JESSE; VO, HUNG THE
To: CERCACOR LABORATORIES, INC.
Reel/Frame 073474/0082 →
CHANGE OF NAME Recorded Mar 21, 2024
From: CERCACOR LABORATORIES, INC.
To: WILLOW LABORATORIES, INC.
Reel/Frame 066867/0264 →
Continuity (2)
Provisional Application 63037973 · Jun 11, 2020
Related Publication 20210386382A1 · Dec 16, 2021
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