IP Library Granted Patent US 11,559,701
Granted Patent B2
US 11,559,701 · App. 17/350,212 · Granted Jan 24, 2023

Method and apparatus to facilitate administering therapeutic radiation to a heterogeneous body

Inventors: Zheyong Fan (Espoo, FI); Linda Laakkonen (Helsinki, FI); Ari Harju (Espoo, FI)
Assignee: Varian Medical Systems International AG
A61N5/1031A61N5/1075A61N5/1077A61N2005/1076
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Quick Facts
Patent No.
US 11,559,701
App. No.
17/350,212
Granted
Jan 24, 2023
Kind
B2
Abstract

These teachings facilitate the administration of therapeutic radiation to a heterogeneous patient volume using a radiation beam source. More particularly, these teachings provide for determining a cross-sectional size of a radiation beam as corresponds to that radiation beam source and also for determining density information corresponding to the aforementioned heterogeneous body. These teachings then provide for generating a three-dimensional radiation dose calculation for the heterogeneous body using a control circuit configured as a convolution/superposition based dose calculator using a three-dimensional energy-spreading kernel. By one approach, these teachings provide for the calculator scaling total energy released per mass as a function of the cross-sectional size and energy of the radiation beam and the aforementioned density information.

Claims (39)

1. A method to facilitate the administration of therapeutic radiation to a heterogeneous patient volume using a radiation beam source, the method comprising:

determining a cross-sectional size of a radiation beam as corresponds to the radiation beam source;

determining density information corresponding to a body comprising at least one of a phantom and the heterogeneous patient volume;

generating a three-dimensional radiation dose calculation for the body using a control circuit configured as a convolution/superposition based dose calculator using a three-dimensional energy-spreading kernel, wherein the calculator scales total energy released per mass as a function of both the cross-sectional size of the radiation beam and the density information.

2. The method of claim 1 wherein the heterogeneous patient volume comprises at least one of:

a patient target volume; and

an organ at risk.

3. The method of claim 2 wherein the patient target volume comprises, at least in part, lung tissue.

4. The method of claim 1 wherein the calculator scales downwardly the total energy released per mass for portions of the body having a relatively lower density and scales upwardly the total energy released per mass for portions of the body having a relatively higher density.

5. The method of claim 1 wherein the calculator is further configured to convolve scaled total energy released per mass information at a given interaction site with a primary kernel for a reference density material.

6. The method of claim 1 wherein the calculator is configured to scale the total energy released per mass by using a scaling factor that is modeled as a function of an effective beam size and density at a particular point in the body.

7. The method of claim 1 further comprising:

by the control circuit:

generating a radiation treatment plan as a function, at least in part, of the three-dimensional radiation dose calculation.

8. The method of claim 7 further comprising:

administering therapeutic radiation to the heterogeneous patient volume per the radiation treatment plan.

9. An apparatus to facilitate the administration of therapeutic radiation to a heterogeneous patient volume using a radiation beam source, the apparatus comprising:

a memory having stored therein:

a cross-sectional size of a radiation beam as corresponds to the radiation beam source; and

density information corresponding to a body comprising at least one of a phantom and the heterogeneous patient volume;

a control circuit operably coupled to the memory and configured as a convolution/superposition based dose calculator using a three-dimensional energy-spreading kernel to generate a three-dimensional radiation dose calculation for the heterogeneous patient volume, wherein the calculator scales total energy released per mass as a function of both the cross-sectional size of the radiation beam and the density information.

10. The apparatus of claim 9 wherein the heterogeneous patient volume comprises at least one of:

a patient target volume; and

an organ at risk.

11. The apparatus of claim 10 wherein the patient target volume comprises, at least in part, lung tissue.

12. The apparatus of claim 9 wherein the calculator scales downwardly the total energy released per mass for portions of the body having a relatively lower density and scales upwardly the total energy released per mass for portions of the body having a relatively higher density.

13. The apparatus of claim 9 wherein the calculator is further configured to convolve scaled total energy released per mass information at a given interaction site with a primary kernel for a reference density material.

14. The apparatus of claim 9 wherein the calculator is configured to scale the total energy released per mass by using a scaling factor that is modeled as a function of an effective beam size and density at a particular point in the body.

15. The apparatus of claim 9 wherein the control circuit is further configured to:

generate a radiation treatment plan as a function, at least in part, of the three-dimensional radiation dose calculation.

16. The apparatus of claim 15 further comprising:

a radiation treatment platform operably coupled to the control circuit and configured to administer therapeutic radiation to the heterogeneous patient volume per the radiation treatment plan.

17. A non-transitory memory having instructions stored therein, which instructions, when executed by a control circuit, cause the control circuit to:

determine a cross-sectional size of a radiation beam as corresponds to a radiation beam source;

determine density information corresponding to a body comprising at least one of a phantom and a heterogeneous patient volume;

serve as a convolution/superposition based dose calculator using a three-dimensional energy-spreading kernel to generate a three-dimensional radiation dose calculation for the heterogeneous patient volume, wherein the calculator scales total energy released per mass as a function of both the cross-sectional size of the radiation beam and the density information.

18. The non-transitory memory of claim 17 wherein the calculator is configured to scale downwardly the total energy released per mass for portions of the body having a relatively lower density and scale upwardly the total energy released per pass for portions of the body having a relatively higher density.

19. The non-transitory memory of claim 17 wherein the calculator is further configured to convolve scaled total energy released per mass information at a given interaction site with a primary kernel for a reference density material.

20. The non-transitory memory of claim 17 wherein the calculator is configured to scale the total energy released per mass by using a scaling factor that is modeled as a function of an effective beam size and density at a particular point in the body.

Assignments (2)
MERGER Recorded Jan 13, 2023
From: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 062388/0086 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 17, 2021
From: FAN, ZHEYONG; LAAKKONEN, LINDA; HARJU, ARI
To: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
Reel/Frame 056574/0693 →
Continuity (1)
Related Publication 20220401756A1 · Dec 22, 2022
Cited By (2)
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