Smart pseudo-palate for linguistic and biomedical applications
In one aspect, the disclosure relates to a smart pseudo-palate for use in a Smart Electropalatograph (EPG) for Linguistic and Medical Applications (SELMA) system. In one aspect, the pseudo-palate is constructed from a thin, flexible polymer membrane and having an embedded electrode array. The pseudo-palate is configured to detect tongue contacts during speech while causing minimal disturbance or interference with speech motion. The disclosed pseudo-palate in the SELMA system is integrated with a microcontroller, wireless electronic module, and external readout app. The disclosure, in another aspect, relates to integration of the pseudo-palate with a smart sports/health mouth guard containing a series of sensors for monitoring head impacts, body temperature, and heart rate. The SELMA system is capable of automated detection of neurological conditions and brain injury including, but not limited to, concussion, and neurological movement disorders, using acoustic, articulatory, and other biosignals from the device using deep data analysis.
1. A pseudo-palate comprising:
a flexible material comprising an anterior end and a posterior end;
a plurality of detecting electrodes embedded in the flexible material, each having a diameter from about 100 μm to about 1 mm in diameter and a thickness of about 200 nm;
a plurality of tracing lines having a width of from about 5 μm to about 50 μm embedded in the flexible material and each connected to a respective electrode of the plurality of electrodes, wherein the tracing lines comprises a width of from about 5 μm to about 50 μm;
a wireless microprocessor module adapted to be positioned along an outer wall of a first posterior portion of the subject's upper gums;
a battery adapted to be positioned along an outer wall of a second posterior portion of the subject's upper gums;
a first wire electrically connected to the plurality of tracing lines and extending from the posterior end of the flexible material and adapted to surround a first posterior-lateral corner of the subject's upper gum to electrically connect to the wireless microprocessor module; and
a second wire electrically connected to the plurality of tracing lines and extending from the posterior end of the flexible material and adapted to surround a second posterior-lateral corner of the subject's upper gum to electrically connect to the battery;
wherein the pseudo-palate is from about 0.1 mm to about 0.2 mm thick, and wherein the plurality of electrodes are configured for resistive sensing of tongue contact with a subject's hard palate.
2. The pseudo-palate of claim 1 , wherein the electrodes comprise gold, titanium, platinum, chromium, nickel, copper, silver, or a combination thereof.
3. The pseudo-palate of claim 1 , wherein the pseudo-palate comprises from 64 to 4096 electrodes.
4. The pseudo-palate of claim 1 , wherein the tracing lines comprise gold, titanium, platinum, nickel, copper, silver, or a combination thereof.
5. The pseudo-palate of claim 1 , wherein the flexible material comprises polydimethylsiloxane (PDMS), porous PDMS, polymethylmethacrylate (PMMA), polyimide (PI), polyurethane (PU), epoxy, or a combination thereof.
6. The pseudo-palate of claim 1 , further comprising a mouth guard, a pressure sensor, a temperature sensor, an inertia sensor, an accelerometer, a gyroscope, a magnetometer, an infrared sensor for monitoring impacts, a heart rate monitor, or any combination thereof.
7. The pseudo-palate of claim 1 , wherein the pseudo-palate is disposable.
8. A pseudo-palate comprising:
a flexible material comprising an anterior end and a posterior end;
a top array comprising a plurality of rows of electrodes and a bottom array comprising a plurality of columns of electrodes embedded in the flexible material, wherein the top array is disposed over the bottom array and are separated by a gap such that when the pseudo-palate is worn by a subject, the top array is close to a subject's hard palate than the bottom array and the gap is adapted to decrease when a tongue contacts the subject's hard palate,
a first straight-line interconnects, each configured to electrically connect electrodes along a respective row of the plurality of rows of electrodes;
a second straight-line interconnects, each configured to electrically connect electrodes along a respective column of the plurality of columns of electrodes;
wherein each electrode of the plurality of row of electrodes and the plurality of column electrodes has a diameter from 100 μm to 1 mm in diameter and a thickness of about 200 nm;
a wireless microprocessor module adapted to be positioned along an outer wall of a first posterior portion of the subject's upper gums;
a battery adapted to be positioned along an outer wall of a second posterior portion of the subject's upper gums;
a first wire electrically connected to the first and second straight-line interconnects extending from the posterior end of the flexible material and adapted to surround a first posterior-lateral corner of the subject's upper gum to electrically connect to the wireless microprocessor module; and
a second wire electrically connected to the first and second straight-line interconnects of the flexible material extending from the posterior end of the flexible material and adapted to surround a second posterior-lateral corner of the subject's upper gum to electrically connect to the battery;
wherein the pseudo-palate is from 60 μm to 200 μm thick; and
wherein the plurality of electrodes are configured for capacitive sensing of tongue contact with the subject's hard palate.
9. The pseudo-palate of claim 8 , wherein the top array of electrodes and the bottom array of electrodes comprise gold, titanium, platinum, nickel, chromium, copper, silver, or a combination thereof.
10. The pseudo-palate of claim 8 , wherein the flexible material comprises polydimethylsiloxane (PDMS), porous PDMS, polymethylmethacrylate (PMMA), polyimide (PI), polyurethane (PU), epoxy, or a combination thereof.
11. The pseudo palate of claim 8 , further comprising a pressure sensor, a temperature sensor, an inertia sensor, an accelerometer, a gyroscope, a magnetometer, an infrared sensor for monitoring impacts, a heart rate monitor, or a combination thereof.
12. The pseudo palate of claim 8 , wherein the pseudo-palate is disposable.
13. A method for diagnosing a neurological condition in a subject, the method comprising:
(a) fitting the subject with the pseudo-palate of claim 8 ;
(b) requiring the subject to perform at least one vocal task;
(c) collecting acoustic data and data from the pseudo-palate generated by the performance of the at least one vocal task;
(d) comparing the acoustic data and data from the pseudo-palate to a data set from healthy subjects and subjects having diagnosed neurological conditions performing the same at least one vocal task; and
(e) diagnosing the neurological condition.
14. The method of claim 13 , wherein the neurological condition comprises a traumatic brain injury, Parkinson's disease, dyspraxia, dysarthria, congenital sensory neuropathy, schizophrenia, depression, fatigue, stress, or a combination thereof.
15. The pseudo palate of claim 1 , wherein the gap comprises a polydimethylsiloxane insulator layer.