Trace element solution
A trace element solution comprises at least the following metals: zinc; manganese; selenium; and copper; and which comprises Vitamin B12. The solution furthermore comprises butaphosphan to stabilize the Vitamin B12 and the inclusion of butaphosphan may have synergistic activity with the minerals.
1 . An injectable trace element solution, the solution comprising at least the following metals:
(a) 24 mg/ml zinc;
(b) 4 mg/ml manganese;
(c) 2 mg/ml selenium;
(d) 6 mg/ml copper;
at least 0.6 mg/ml Vitamin B12; and
butaphosphan,
wherein precipitation is visually absent in the injectable trace element solution exposed at 25° C. and 60% relative humidity for 3 months.
2 . The injectable trace element solution of claim 1 , wherein the zinc is derived from zinc oxide.
3 . The injectable trace element solution of claim 1 , wherein the copper is derived from copper carbonate or copper sulphate pentahydrate.
4 . The injectable trace element solution of claim 1 , wherein the selenium is derived from sodium selenite anhydrous.
5 . The injectable trace element solution of claim 1 , wherein:
the manganese is derived from manganese carbonate;
the zinc is derived from zinc oxide;
the copper is derived from copper carbonate or copper sulphate pentahydrate, and
the selenium is derived from sodium selenite anhydrous.
6 . The injectable trace element solution of claim 1 further comprising benzyl alcohol.
7 . The injectable trace element solution of claim 1 further comprising chromium.
8 . The injectable trace element colution of claim 1 further comprising iodine.
9 . An injectable trace element solution, the solution comprising at least the following metals:
(a) 24 mg/ml zinc;
(b) 4 mg/ml manganese;
(c) 2 mg/ml selenium;
(d) 6 mg/ml copper;
at least 0.6 mg/ml Vitamin B12; and
butaphosphan,
wherein the Vitamin B12 is chemically stable in the injectable trace element solution exposed at 25° C. and 60% relative humidity for 3 months.
10 . The injectable trace element solution of claim 9 , wherein the Vitamin B12 is chemically stable in the injectable trace element solution exposed at 25° C. and 60% relative humidity for 6 months.
11 . The injectable trace element solution of claim 9 , wherein precipitation is visually absent in the injectable trace element solution exposed at 25° C. and 60% relative humidity for 3 months.
12 . The injectable trace element solution of claim 10 , wherein precipitation is visually absent in the injectable trace element solution exposed at 25° C. and 60% relative humidity for 3 months.