IP Library Granted Patent US 12,150,858
Granted Patent B2
US 12,150,858 · App. 17/357,115 · Granted Nov 26, 2024

Low-profile intercranial device

Inventor: Chad Gordon (Cockeysville, MD)
Assignee: The Johns Hopkins University
A61F2/2875A61B5/0006A61B5/0013A61B5/0036A61B5/0066A61B5/031A61B5/369A61B5/4836A61B5/686A61B5/6868A61F2/30942A61N1/00A61N1/0531A61N1/3605A61B5/0084A61B5/4839A61F2002/3067A61F2002/3068A61F2002/30948A61F2/482A61M5/14276A61M2210/0687G06T2207/20128
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Quick Facts
Patent No.
US 12,150,858
App. No.
17/357,115
Granted
Nov 26, 2024
Kind
B2
Abstract

Provided is a functional, low-profile intercranial device (LID). The LID includes a base portion; at least one cavity associated with the base portion and configured to accept at least one functional component; and at least one conduit having a first end in communication with the at least one cavity. The at least one functional component includes a medicinal, electronic, or optic therapeutic. The at least one conduit is configured to accept the medicinal therapeutic and a second end configured to dispense the therapeutic.

Claims (25)

1. A functional, low-profile intercranial device (LID), comprising:

a base portion comprising a cranial or craniofacial implant having a geometry that is configured to conform with a resected portion of a skull of a patient and has a thickness configured to provide strategic bulking for concomitant temporal hollowing correction, the base portion including a curvature specific to that of the skull to ensure a fit with absence of gaps along a periphery of the base portion, and the base portion being configured to address a patient clinical care algorithm both from a skull bone perspective and from an underlying regional brain perspective such that the cranial or craniofacial implant is configured to correct deformities and/or defects by placement at least partially within the resected portion of the skull during a surgical procedure to replace missing bone and provide cerebral protection from injury;

at least one functional component;

at least one cavity formed within the base portion as a void space within the base portion, the at least one cavity configured to encase the at least one functional component; and at least one conduit comprising an end configured to be in communication with the at least one cavity, wherein an orientation of at least one of the at least one conduit or the at least one functional component is configured to be customizable for the patient.

2. The functional, low-profile intercranial device of claim 1 , wherein the conduit is configured to provide for transit of a therapeutic from a functional component, of the at least one functional component, to a brain of the patient.

3. The functional, low-profile intercranial device claim 1 , wherein the conduit is configured to provide for transit of computer-guided responsive stimulation from a functional component, of the at least one functional component, to a brain of the patient.

4. The functional, low-profile intercranial device of claim 1 , wherein the at least one functional component is detachably connected to the base portion.

5. The functional, low-profile intercranial device of claim 1 , wherein the conduit is configured to provide for transit of signals from a functional component, of the at least one functional component, to a brain of the patient.

6. The functional, low-profile intercranial device of claim 1 , wherein the cranial or craniofacial implant is radiolucent.

7. The functional, low-profile intercranial device of claim 1 , wherein the cranial or craniofacial implant comprises polymethylmethacrylate (PMMA), polyether ether ketone (PEEK), or polyethylene.

8. The functional, low-profile intercranial device of claim 1 , wherein the cranial or craniofacial implant is a custom cranial or craniofacial implant.

9. A functional intercranial implant, comprising:

a base portion comprising a cranial or craniofacial implant having (i) a first portion with a geometry that is configured to conform with a resected portion of a skull of a patient to ensure a fit with absence of gaps along a periphery of the base portion and (ii) a second portion of increased thickness configured to provide strategic bulking for concomitant temporal hollowing correction, the second portion having space for accommodating a functional component, the cranial or craniofacial implant being configured to address a patient clinical care algorithm both from a skull bone perspective and from an underlying regional brain perspective such that the cranial or craniofacial implant is configured to correct deformities and/or defects by placement at least partially within the resected portion of the skull during a surgical procedure to replace missing bone and provide cerebral protection from injury; and

a conduit comprising an end configured to be in communication with the functional component, an orientation of at least the conduit or the functional component being configurable to be customizable for the patient.

10. The functional intercranial implant of claim 9 , wherein the functional component is configured to deliver a medicinal therapeutic.

11. The functional intercranial implant of claim 10 , wherein the end is a first end configured to be in communication with the functional component to accept the medicinal therapeutic, and wherein the conduit further comprising a second end configured to dispense the medicinal therapeutic.

12. The functional intercranial implant of claim 9 , wherein the conduit is configured to provide for transit of a therapeutic.

13. The functional intercranial implant of claim 9 , wherein the conduit is configured to provide for transit of computer-guided responsive stimulation from the functional component.

14. The functional intercranial implant of claim 9 , wherein the conduit is configured to provide for transit of signals from the functional component to a brain of the patient.

15. The functional intercranial implant of claim 9 , wherein the cranial or craniofacial implant is radiolucent.

16. The functional intercranial implant of claim 9 , wherein the cranial or craniofacial implant comprises polymethylmethacrylate (PMMA).

17. The functional intercranial implant of claim 9 , wherein the cranial or craniofacial implant is a custom cranial or craniofacial implant.

18. The functional intercranial implant of claim 9 , wherein the first portion has a thickness of around 4-12 millimeters.

19. The functional intercranial implant of claim 9 , wherein the functional component is a medicinal pump.

20. The functional intercranial implant of claim 9 , wherein the base portion comprises at least one porous surface through which a syringe needle can penetrate or at least one access port for accepting the syringe needle.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 24, 2021
From: GORDON, CHAD
To: THE JOHNS HOPKINS UNIVERSITY
Reel/Frame 056657/0335 →
Continuity (3)
Continuation 15756010
Provisional Application 62214702 · Sep 4, 2015
Related Publication 20210322172A1 · Oct 21, 2021