Low-profile intercranial device

1. An implant, comprising:

a base portion comprising a cranial or craniofacial implant for placement within a resected portion of a skull of a patient, the cranial or craniofacial implant comprising a polymer, metal, bioengineered material, or combinations thereof, the cranial or craniofacial implant being shaped and dimensioned to address a patient clinical care algorithm both from a skull bone perspective and from an underlying regional brain perspective such that the cranial or craniofacial implant corrects deformities and/or defects by placement at least partially within the resected portion of the skull during a surgical procedure replacing missing bone and providing cerebral protection from injury, and the base portion including a curvature specific to that of the skull to ensure a fit with absence of gaps along a periphery of the base portion;

at least one cavity formed within the base portion, the cavity being and configured to accept at least one functional component for delivering a medicinal therapeutic; and

at least one conduit comprising a first end in communication with the cavity and configured to accept the medicinal therapeutic and a second end configured to dispense the medicinal therapeutic,

wherein an orientation of the at least one conduit and the at least one functional component are customized to a patient-specific scenario.

2. The implant of claim 1 , further including a pump and wherein at least a portion of the pump is encased in the base portion.

3. The implant of claim 1 , further including the medicinal therapeutic includes one or more therapies selected from the group consisting of anti-tumor, anti-seizure, anti-parkinson, anti-hydrocephalus, anti-ADHD, anti-alzheimer's, anti-pain, energy-enhancing, and combinations thereof.

4. The implant of claim 1 , wherein the cranial or craniofacial implant fills the resected portion of the skull.

5. The implant of claim 1 , wherein the conduit comprises a catheter.

6. The implant of claim 1 , wherein the functional component is detachably connected to the base portion.

7. The implant of claim 6 , wherein the base portion comprises at least one porous surface through which a syringe needle can penetrate.

8. The implant of claim 6 , wherein the base portion comprises at least one access port for accepting a syringe needle.

9. The implant of claim 1 , wherein at least a portion of the functional component is encased in the base portion.

10. The implant of claim 1 , wherein the conduit extends between the cavity and a diseased portion of brain parenchyma, a dead-space cavity following brain tumor resection, a blood vessel, a neuron or a ventricle.

11. The implant of claim 1 , wherein the base portion comprises internal supports extending through an internal portion thereof.

12. The implant of claim 1 , wherein the cranial or craniofacial implant is a custom cranial or craniofacial implant.

13. An implant, comprising:

a base portion comprising a cranial or craniofacial implant for placement within a resected portion of a skull of a patient, the cranial or craniofacial implant comprising a polymer, metal, bioengineered material, or combinations thereof, the cranial or craniofacial implant being shaped and dimensioned to address a patient clinical care algorithm both from a skull bone perspective and from an underlying regional brain perspective such that the cranial or craniofacial implant corrects deformities and/or defects by placement at least partially within the resected portion of the skull during a surgical procedure replacing missing bone and providing cerebral protection from injury, and the base portion including a curvature specific to that of the skull to ensure a fit with absence of gaps along a periphery of the base portion;

at least one cavity associated with the base portion and configured to accept at least one functional component, wherein the functional component is a medicine dispensing device; and

at least one conduit,

wherein an orientation of the at least one conduit and the at least one functional component are customized to a patient-specific scenario.

14. The implant of claim 13 , wherein the at least one conduit comprises a first end in communication with the cavity and configured to accept a medicinal therapeutic contained within the cavity or the functional component and a second end configured to dispense the medicinal therapeutic.

15. The implant of claim 13 , further including a medicinal therapeutic comprising one or more therapies selected from the group consisting of anti-tumor, anti-seizure, anti-parkinson, anti-hydrocephalus, anti-ADHD, anti-alzheimer's, anti-pain, energy-enhancing, and combinations thereof.

16. The implant of claim 15 , wherein the cranial or craniofacial implant includes the at least one conduit, and

wherein the at least one conduit comprises a first end in communication with the cavity and configured to accept the medicinal therapeutic and a second end configured to dispense the medicinal therapeutic.

17. The implant of claim 13 , wherein the functional component is detachably connected to the base portion.

18. The implant of claim 13 , further including at least one access port for accepting a syringe needle such that the syringe needle can penetrate and access a void space defined by the functional component.

19. The implant of claim 13 , further including a pump and wherein at least a portion of the pump is encased in the base portion.

20. The implant of claim 13 , wherein the base portion comprises internal supports extending through an internal portion thereof.

21. The implant of claim 13 , wherein the cranial or craniofacial implant is a custom cranial or craniofacial implant.