IP Library › Granted Patent US 12,213,884
Granted Patent B2
US 12,213,884 · App. 17/357,249 · Granted Feb 4, 2025

Low-profile intercranial device

Inventor: Chad Gordon (Cockeysville, MD)
Assignee: The Johns Hopkins University
A61F2/2875A61B5/0006A61B5/0013A61B5/0036A61B5/0066A61B5/031A61B5/369A61B5/4836A61B5/686A61B5/6868A61F2/30942A61N1/00A61N1/0531A61N1/3605A61B5/0084A61B5/4839A61F2002/3067A61F2002/3068A61F2002/30948A61F2/482A61M5/14276A61M2210/0687G06T2207/20128
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Quick Facts
Patent No.
US 12,213,884
App. No.
17/357,249
Filed
Jun 24, 2021
Granted
Feb 4, 2025
Kind
B2
Art Unit
3774
USPC
623/17.19
Abstract

Provided is a functional, low-profile intercranial device (LID). The LID includes a base portion; at least one cavity associated with the base portion and configured to accept at least one functional component; and at least one conduit having a first end in communication with the at least one cavity. The at least one functional component includes a medicinal, electronic, or optic therapeutic. The at least one conduit is configured to accept the medicinal therapeutic and a second end configured to dispense the therapeutic.

Claims (29)

1. A cranial device, comprising:

a cranial or craniofacial implant made of polymethylmethacrylate (PMMA), polyether ether ketone (PEEK), or polyethylene, the cranial or craniofacial implant being shaped and dimensioned for placement at least partially within a resected portion of a patient's skull during a surgical procedure, wherein the cranial or craniofacial implant includes a curvature specific to that of the skull to ensure a fit with absence of gaps along a periphery of the cranial or craniofacial implant, and being shaped and dimensioned to address a patient clinical care algorithm both from a skull bone perspective and from an underlying regional brain perspective such that the cranial or craniofacial implant corrects deformities and/or defects by placement at least partially within the resected portion of the skull during a surgical procedure replacing missing bone and providing cerebral protection from injury;

at least one functional component providing for ultrasound functionalities; and

at least one cavity formed in the cranial or craniofacial implant, the at least one cavity being shaped and dimensioned to house the at least one functional component, such that the at least one functional component is encased within a void-space defined by the at least one cavity, and the at least one functional component and the cavity are customized to be patient-specific.

2. The cranial device of claim 1 , wherein the cranial or craniofacial implant is radiolucent.

3. The cranial device of claim 1 , wherein the at least one functional component is configured to monitor a physiological condition.

4. The cranial device of claim 1 , wherein the at least one functional component is configured to perform imaging.

5. The cranial device of claim 4 , wherein the imaging comprises optical coherence tomography (OCT).

6. The cranial device of claim 1 , wherein the at least one functional component is configured to perform intracranial pressure (ICP) monitoring or vital sign monitoring.

7. The cranial device of claim 1 , wherein the cranial or craniofacial implant is made of the PMMA.

8. The cranial device of claim 1 , wherein the cranial or craniofacial implant is made of PEEK.

9. The cranial device of claim 1 , wherein the cranial or craniofacial implant is made of the polyethylene.

10. A cranial device, comprising:

a cranial or craniofacial implant shaped and dimensioned for placement at least partially within a resected portion of a patient's skull during a surgical procedure, wherein the cranial or craniofacial implant includes a curvature specific to that of the skull to ensure a fit with absence of gaps along a periphery of the cranial or craniofacial implant, and being shaped and dimensioned to address a patient clinical care algorithm both from a skull bone perspective and from an underlying regional brain perspective such that the cranial or craniofacial implant corrects deformities and/or defects by placement at least partially within the resected portion of the skull during a surgical procedure replacing missing bone and providing cerebral protection from injury;

at least one functional component providing for ultrasound functionalities; and

at least one cavity formed in the cranial or craniofacial implant, the at least one cavity being shaped and dimensioned to house the at least one functional component, such that the at least one functional component is encased within a void-space defined by the at least one cavity, and the at least one functional component and the cavity are customized to be patient-specific.

11. The cranial device of claim 10 , wherein the cranial or craniofacial implant is made of polymethylmethacrylate (PMMA).

12. The cranial device of claim 10 , wherein the cranial or craniofacial implant is made of polyether ether ketone (PEEK).

13. The cranial device of claim 10 , wherein the cranial or craniofacial implant is made of polyethylene.

14. A cranial device, comprising:

a cranial or craniofacial implant that is radiolucent, the cranial or craniofacial implant being shaped and dimensioned for placement at least partially within a resected portion of a patient's skull during a surgical procedure, wherein the cranial or craniofacial implant includes a curvature specific to that of the skull to ensure a fit with absence of gaps along a periphery of the cranial or craniofacial implant, and being shaped and dimensioned to address a patient clinical care algorithm both from a skull bone perspective and from an underlying regional brain perspective such that the cranial or craniofacial implant corrects deformities and/or defects by placement at least partially within the resected portion of the skull during a surgical procedure replacing missing bone and providing cerebral protection from injury;

at least one functional component providing for ultrasound functionalities; and

at least one cavity formed in the cranial or craniofacial implant, the at least one cavity being shaped and dimensioned to house the at least one functional component, such that the at least one functional component is encased within a void-space defined by the at least one cavity, wherein an orientation of at least one of the at least one functional component or the cavity are customizable.

15. The cranial device of claim 14 , wherein the cranial or craniofacial implant is made of polymethylmethacrylate (PMMA).

16. The cranial device of claim 14 , wherein the cranial or craniofacial implant is made of polyether ether ketone (PEEK).

17. The cranial device of claim 14 , wherein the cranial or craniofacial implant is made of polyethylene.

18. The cranial device of claim 14 , wherein the at least one functional component is configured to monitor a physiological condition.

19. The cranial device of claim 14 , wherein the at least one functional component is configured to perform imaging.

20. The cranial device of claim 14 , wherein the at least one functional component is configured to perform duplex ultrasound.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 24, 2021
From: GORDON, CHAD
To: THE JOHNS HOPKINS UNIVERSITY
Reel/Frame 056658/0155 →
Continuity (3)
Continuation 15756010
Provisional Application 62214702 · Sep 4, 2015
Related Publication 20210315702A1 · Oct 14, 2021
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