IP Library Granted Patent US 11,896,848
Granted Patent B2
US 11,896,848 · App. 17/375,586 · Granted Feb 13, 2024

Methods for setup corrections in radiation therapy

Inventors: Jayakrishnan Janardhanan (Union City, CA); Michael Kirk Owens (San Francisco, CA)
Assignee: RefleXion Medical, Inc.
A61N5/1049A61N5/103A61N5/107A61N5/1031A61N5/1037A61N5/1039A61N5/1045A61N5/1047A61N5/1048A61N5/1081A61N5/1082A61N2005/1052A61N2005/1061A61N2005/1091
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Quick Facts
Patent No.
US 11,896,848
App. No.
17/375,586
Granted
Feb 13, 2024
Kind
B2
Abstract

Disclosed herein are methods for patient setup and registration for the irradiation of target tissue regions. A method for positioning a patient for radiation therapy may include acquiring an image of a first patient target region and a second patient target region. A first set of patient position-shift vectors may be calculated based on the acquired image and a treatment planning image of the first patient target region. A second set of patient position-shift vectors may be calculated based on the acquired image, a treatment planning image of the second patient target region, and the first set of patient position-shift vectors. The patient may be positioned according to the first set of patient position-shift vectors in a first location. The patient may be moved to a second location and positioned according to the second set of patient position-shift vectors.

Claims (26)

1. A method for positioning a patient for a radiation therapy, the method comprising:

acquiring an image of a first patient target region and a second patient target region;

calculating a first set of patient position-shift vectors based on the acquired image and a first treatment planning image of the first patient target region;

calculating a second set of patient position-shift vectors based on the acquired image, a second treatment planning image of the second patient target region, and the first set of patient position-shift vectors;

positioning the patient at a first location according to the first set of patient position-shift vectors; and

positioning the patient at a second location according to the second set of patient position-shift vectors.

2. The method of claim 1 , wherein positioning the patient at the first location according to the first set of patient position-shift vectors comprises moving a radiation therapy patient platform and/or a therapeutic radiation source according to the first set of patient position-shift vectors.

3. The method of claim 2 , wherein moving the radiation therapy patient platform comprises moving the radiation therapy patient platform along its X-axis, and/or Y-axis, and/or Z-axis.

4. The method of claim 2 , wherein moving the radiation therapy patient platform comprises adjusting a yaw and/or a pitch of the radition therapy patient platform and moving the therapeutic radiation source comprises adjusting a roll of a gantry to which the therapeutic radiation source is coupled.

5. The method of claim 1 , wherein positioning the patient at the second location according to the second set of patient position-shift vectors comprises moving a radiation therapy patient platform according to the second set of patient position-shift vectors.

6. The method of claim 5 , wherein positioning the patient at the second location according to the second set of patient position-shift vectors comprises moving a therapeutic radiation source according to the second set of patient position-shift vectors.

7. The method of claim 6 , wherein moving the therapeutic radiation source according to the second set of patient position-shift vectors comprises adjusting a roll of a gantry to which the therapeutic radiation source is coupled.

8. The method of claim 5 , wherein moving the radiation therapy patient platform according to the second set of patient position-shift vectors comprises adjusting a yaw and/or a pitch of the radition therapy patient platform.

9. The method of claim 1 , wherein the first treatment planning image and the second treatment planning image are the same treatment planning image.

10. The method of claim 1 , wherein the acquired image is a PET image.

11. The method of claim 1 , wherein the acquired image is a CT image.

12. The method of claim 1 , wherein calculating the first set of patient position-shift vectors and the second set of patient position-shift vectors occurs before a therapeutic radiation source is activated.

13. The method of claim 1 , further comprising:

calculating a first location difference by comparing a location of the first patient target region in the acquired image with a location of the first patient target region in the first treatment planning image;

calculating a second location difference by comparing a location of the second patient target region in the acquired image with a location of the second patient target region in the second treatment planning image; and

generating a notification if the first location difference or the second location difference exceeds a location difference threshold.

14. The method of claim 1 , wherein the first patient target region and the second patient target region comprise one or more tumor regions.

15. The method of claim 14 , wherein the first patient target region comprises a first portion of a tumor and the second patient target region comprises a second portion of the tumor.

16. The method of claim 1 , wherein the first set of patient position-shift vectors and the second set of patient position-shift vectors comprise distance translations and direction translations.

17. The method of claim 16 , wherein the direction translations comprise tilt angles.

18. The method of claim 1 , wherein the first location is associated with a first beam station and the second location is associated with a second beam station adjacent to the first beam station.

Assignments (2)
SECURITY INTEREST Recorded Jul 11, 2022
From: REFLEXION MEDICAL, INC.
To: OXFORD FINANCE LLC
Reel/Frame 060619/0066 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 3, 2021
From: JANARDHANAN, JAYAKRISHNAN; OWENS, MICHAEL KIRK
To: REFLEXION MEDICAL, INC.
Reel/Frame 057179/0259 →
Continuity (3)
Continuation PCTUS2020013927 · Jan 16, 2020
Provisional Application 62793288 · Jan 16, 2019
Related Publication 20210339047A1 · Nov 4, 2021
Cited By (10)
US 12,214,219 US 12,233,286 US 12,251,579 US 12,303,718 US 12,337,196 US 12,420,115 US 12,440,703 US 12,521,571 US 12,551,727 US 12,582,845