IP Library › Granted Patent US 12,201,520
Granted Patent B2
US 12,201,520 · App. 17/393,539 · Granted Jan 21, 2025

Prosthetic heart valve

Inventors: Nathan L. Bennett (Flagstaff, AZ); Joshua A. Sprinkle (Flagstaff, AZ)
Assignee: EDWARDS LIFESCIENCES CORPORATION
A61F2/2418A61F2/2412A61F2/2463A61F2/2427A61F2/246A61F2/2466A61F2210/0014A61F2220/0016A61F2220/005A61F2220/0075A61F2230/0069A61F2250/0069
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Quick Facts
Patent No.
US 12,201,520
App. No.
17/393,539
Granted
Jan 21, 2025
Kind
B2
Abstract

Described embodiments are directed toward centrally-opening leaflet prosthetic valve devices having a leaflet frame and a leaflet construct including one or more leaflets. In some examples, the leaflet construct is coupled to the leaflet frame via a retention element. In some examples, the retention element is in the form of an outer frame that is coaxially arranged with the leaflet frame.

Claims (23)

1. A prosthetic valve, comprising:

a leaflet frame defining a cylinder and including a leaflet frame inner side, a leaflet frame outer side, a leaflet frame outflow edge, and a leaflet frame inflow edge, the leaflet frame further including a leaflet frame central axis and a plurality of leaflet frame commissure posts extending along the leaflet frame central axis, each leaflet frame commissure post defining a post slot therethrough such that the leaflet frame includes a plurality of post slots;

a leaflet construct comprising a plurality of leaflets and a bridge region situated between adjacently situated leaflets, each bridge defining a bridge loop such that the leaflet construct defines a plurality of bridge loops, each bridge loop being situated adjacent to the leaflet frame outer side such that the leaflet construct extends through the plurality of post slots, each of the leaflets including a fold-over portion, the fold-over portion of each of the leaflets being folded around the inflow edge of the leaflet frame to the leaflet frame outer side; and

an outer frame including a plurality of outer frame commissure posts, each outer frame commissure post being disposed within a first bridge loop of the plurality of bridge loops such that a portion of the first bridge loop is outside of the outer frame commissure post in a radial direction, the outer frame further including an outer frame inner side, an outer frame outer side, and an outer frame inflow edge, the leaflet frame being received with an interior region defined by the outer frame, wherein the leaflet frame outer side between the leaflet frame inflow edge and leaflet frame outflow edge of the leaflet frame is situated adjacent to and radially inwardly of the outer frame inner side, wherein the fold-over portion of the leaflet construct is positioned radially between the leaflet frame outer side and the outer frame inner side.

2. The prosthetic valve of claim 1 , wherein the outer frame commissure posts include commissure post tips and wherein the leaflet frame is positioned between the outer frame commissure post tips and a shoulder surface of an annular shoulder of the outer frame.

3. The prosthetic valve of claim 1 , wherein the outer frame comprises a plurality of keystones assembled to form the outer frame.

4. The prosthetic valve of claim 3 , further comprising a ring element disposed about the outer frame.

5. The prosthetic valve of claim 1 , wherein the outer frame includes a shoulder surface situated opposite the outer frame inflow edge and extending into the interior region defined by the outer frame transversely to the central axis, the shoulder surface operably supporting the leaflet frame inflow edge.

6. The prosthetic valve of claim 1 , wherein the leaflet frame is coupled to the outer frame.

7. The prosthetic valve of claim 6 , wherein the leaflet frame, the outer frame, and the leaflet construct each include a plurality of corresponding apertures, and wherein the leaflet frame and the outer frame are coupled together by a securement structure that passes through adjacent apertures of the leaflet frame, outer frame, and leaflet construct and is operable to couple the outer frame to the leaflet frame.

8. The prosthetic valve of claim 7 , wherein the securement structure is a suture.

9. The prosthetic valve of claim 1 , further comprising a sewing cuff coupled to the outer frame.

10. The prosthetic valve of claim 1 , wherein the leaflet construct comprises an ePTFE composite.

11. The prosthetic valve of claim 10 , wherein ePTFE composite comprises perfluorom ethyl vinyl ether and tetrafluoroethylene.

12. A prosthetic valve, comprising:

a leaflet frame including a leaflet frame inner side, a leaflet frame outer side, and a leaflet frame inflow edge, the leaflet frame further including a leaflet frame central axis and a plurality of leaflet frame commissure posts extending along the leaflet frame central axis, each leaflet frame commissure post defining a post slot therethrough such that the leaflet frame includes a plurality of post slots;

a leaflet construct comprising a plurality of leaflets and a bridge region situated between adjacently situated leaflets, each bridge defining a bridge loop such that the leaflet construct defines a plurality of bridge loops, each bridge loop being situated adjacent to the leaflet frame outer side such that the leaflet construct extends through the plurality of post slots,

an outer frame including an outer frame base and a plurality of outer frame commissure posts extending from the outer frame base, each outer frame commissure post being disposed within a first bridge loop of the plurality of bridge loops such that a portion of the first bridge loop is positioned outside of the outer frame commissure post in a radial direction, the outer frame commissure posts including a projection extending into the post slot of the leaflet frame and between two adjacent leaflets extending through the post slot of the leaflet frame.

13. The prosthetic valve of claim 12 , wherein each of the leaflets including a fold-over portion, the fold-over portion of each of the leaflets being folded around the inflow edge of the leaflet frame to the leaflet frame outer side.

14. The prosthetic valve of claim 13 , wherein the outer frame further includes an outer frame inner side, an outer frame outer side, an outer frame inflow edge, the leaflet frame being received with an interior region defined by the outer frame such that the fold-over portion of each of the leaflets is positioned between the outer frame inner side and the leaflet frame outer side, and such that the leaflet construct extends along the leaflet frame inflow edge.

15. The prosthetic valve of claim 14 , wherein the projection is configured to extend away from an inner of the commissure post by an amount sufficient for the projection to extend radially inwardly of the leaflet frame inner side when the leaflet frame is coupled with the outer frame.

16. The prosthetic valve of claim 14 , wherein projection extends only partially into the post slot of the leaflet frame such that an inner surface of the projection terminates radially outwardly of the leaflet frame inner side when the leaflet frame is coupled with the outer frame.

17. The prosthetic valve of claim 12 , wherein each leaflet is secured to a first surface of the outer frame inner side.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 21, 2023
From: W.L. GORE & ASSOCIATES, INC.
To: EDWARDS LIFESCIENCES CORPORATION
Reel/Frame 065021/0654 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 15, 2023
From: BENNETT, NATHAN L; SPRINKLE, JOSHUA A
To: W. L. GORE & ASSOCIATES, INC.
Reel/Frame 062705/0209 →
Continuity (3)
Continuation 16129685 · Sep 12, 2018
Provisional Application 62579763 · Oct 31, 2017
Related Publication 20210361420A1 · Nov 25, 2021
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