Alcohol-free hydrogen peroxide disinfectant compositions and methods of use thereof
Disclosed are low-level hydrogen peroxide aqueous-based disinfectant compositions that are substantially free of or do not contain volatile short chain (C1-C7) alcohols and exhibit broad spectrum antimicrobial/microbicidal activity against a variety of microorganisms including mycobacteria. Also disclosed are methods for using the compositions for the disinfection or sterilization of a variety hard surfaces such as those found in dental, hospital, and clinical environments or in food preparation environments.
1. An aqueous-based disinfecting composition comprising:
(a) hydrogen peroxide at a concentration of 0.3 to 0.7% w/w,
(b) caprylic acid, or salt thereof at a concentration of 0.1 to 5% w/w,
(c) salicylic acid, or salt thereof at a concentration of 0.1 to 5% w/w,
(d) sodium C14-C16 olefin sulfonate at a concentration of 0.1 to 5% w/w, and
(e) water,
wherein the composition does not include or is substantially free of a volatile C1-C7 alcohol, and wherein the pH of the composition is from 1 to 2.
2. The composition of claim 1 , wherein the composition further comprises a sequestering or chelating agent.
3. The composition of claim 2 , wherein the sequestering or chelating agent is etidronic acid (HEDP) at a concentration of 0.1 to 5% w/w.
4. The composition of claim 1 , wherein the composition further comprises formic acid, or salt thereof at a concentration of 0.01 to 5% w/w.
5. The composition of claim 1 , wherein the composition further comprises sodium lauryl sulfate at a concentration of 0.1 to 5% w/w.
6. The composition of claim 1 , wherein, the concentration of caprylic acid, or salt thereof is 0.1 to 1.0% w/w, and wherein the concentration of salicylic acid, or salt thereof is 0.1 to 0.5% w/w.
7. The composition of claim 1 , wherein the composition further comprises a fragrance and/or a dye.
8. A method of disinfecting or sterilizing a surface, the method comprising: contacting the composition of claim 1 with the surface and allowing the composition to remain in contact with the surface for a period of time thereby disinfecting or sterilizing the surface.
9. The method of claim 8 , wherein the period of time is at least 1 minute.
10. The method of claim 8 , wherein the surface is at least a portion of the surface of medical equipment, medical devices, medical tools, or medical instruments.
11. An aqueous-based disinfecting composition comprising:
(a) hydrogen peroxide at a concentration of 0.1 to 0.9% w/w,
(b) one or more linear monocarboxylic acids with a carbon chain length of C5 to C12, or salt thereof, at a concentration of about 0.01 to about 5% w/w,
(c) salicylic acid at a concentration of about 0.01 to about 5% w/w,
(d) one or more sodium olefin sulfonate surfactants at a concentration of about 0.01 to about 5% w/w, and
(e) water,
wherein the composition does not contain or is substantially free of a volatile C1-C7 alcohol, and wherein the pH of the composition is from 0.1 to 2, and
wherein the one or more linear monocarboxylic acids with a carbon chain length of C5 to C12, or salt thereof is caprylic acid (C8), or salt thereof, and/or capric acid (C10), or salt thereof.
12. The composition of claim 11 , wherein the composition further comprises a sequestering or chelating agent.
13. The composition of claim 12 , wherein the sequestering or chelating agent is etidronic acid (HEDP), or salt thereof.
14. The composition of claim 11 , further comprising one or more linear monocarboxylic acids with a carbon chain length of C1 to C4, or salt thereof at a concentration of about 0.01 to about 5% w/w.
15. The composition of claim 14 , wherein the one or more linear monocarboxylic acids with a carbon chain length of C1 to C4, or salt thereof is formic acid.
16. The composition of claim 11 , further comprising one or more sodium C8 to C16 alkyl sulfate surfactants at a concentration of about 0.01 to about 5% w/w.
17. The composition of claim 16 , wherein the one or more sodium C8 to C16 alkyl sulfate surfactants is sodium lauryl sulfate.
18. The composition of claim 11 , wherein the sodium olefin sulfonate surfactant is sodium C14-C16 olefin sulfonate.
19. The composition of claim 11 , wherein the one or more linear monocarboxylic acids with a carbon chain length of C5 to C12, or salt thereof is caprylic acid (C8), or salt thereof at a concentration of 0.1 to 1.0% w/w; and wherein the salicylic acid, or salt thereof is at a concentration of 0.1 to 0.5% w/w.
20. The composition of claim 11 , wherein the composition further comprises a fragrance and/or dye.
21. The composition of claim 11 , wherein the composition is capable of exhibiting antimicrobial or bactericidal activity against microorganisms on a surface when the composition is in contact with the microorganisms for at least 1 minute, wherein the microorganisms are one or more of gram-positive bacteria, gram-negative bacteria, fungi, yeasts, molds, or mycobacteria.