IP Library › Granted Patent US 11,712,226
Granted Patent B2
US 11,712,226 · App. 17/410,364 · Granted Aug 1, 2023

Integrated system for ultrasound imaging and therapy

Inventors: Anshuman Bhuyan (Milpitas, CA); Jung Woo Choe (Sunnyvale, CA); Amin Nikoozadeh (Palo Alto, CA); Butrus T. Khuri-Yakub (Palo Alto, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
A61B8/54A61B8/4483A61N7/00A61N7/02B06B1/0215B06B1/0292A61N2007/0021A61N2007/0052B06B2201/76
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Quick Facts
Patent No.
US 11,712,226
App. No.
17/410,364
Granted
Aug 1, 2023
Kind
B2
Abstract

Ultrasound imaging and therapy with the same array of capacitive micromachined ultrasonic transducers is provided. The electronics includes a per-pixel switch for each transducer element. The switches provide an imaging mode driven completely by on-chip electronics and a therapy mode where off-chip pulsers provide relatively high voltages to the transducer elements.

Claims (45)

1. An apparatus with a plurality of ultrasound modes,

the apparatus comprising:

an array of ultrasound transducer elements;

imaging circuitry configured to perform ultrasound imaging with the array of ultrasound transducer elements in a first mode;

a pulser configured to provide a voltage to an ultrasound transducer element of the array of ultrasound transducer elements in a second mode, wherein the array generates continuous wave ultrasound or quasi-continuous wave ultrasound in the second mode;

a switch configured to electrically connect the pulser to the ultrasound transducer of the array for the second mode and to electrically disconnect the pulser from the ultrasound transducer of the array for the first mode, the switch being on a chip, and the pulser being external to the chip such that power dissipation associated with the pulser occurs external to the chip; and

additional switches, wherein the switch and the additional switches are included in a plurality of switches, and wherein each of the ultrasound transducer elements of the array is connected to one switch of the plurality of switches.

2. The apparatus of claim 1 , wherein the imaging circuitry is on the chip.

3. The apparatus of claim 1 , further comprising a line switch configured to selectively electrically connect the pulser to the switch.

4. The apparatus of claim 1 , wherein the switch comprises transistors arranged to pass a voltage from the pulser that is greater than a gate-to-source voltage of any one of the transistors.

5. The apparatus of claim 1 , wherein the ultrasound transducer elements are capacitive micromachined ultrasonic transducers.

6. The apparatus of claim 1 , further comprising an inductor connected in series between the switch and the ultrasound transducer element, wherein a combination of the inductor and the ultrasound transducer element is electrically resonant at an ultrasound frequency of the second mode.

7. The apparatus of claim 1 , wherein the array of ultrasound transducer elements comprises at least 32 ultrasound transducer elements in a first dimension and 32 ultrasound transducer elements in a second dimension.

8. The apparatus of claim 1 , further comprising additional pulsers having phases spaced with each other, wherein switches of the plurality of switches are configured to electrically connect the additional pulsers to the array in the second mode and to electrically disconnect the additional pulsers from the array in the first mode.

9. An apparatus with a plurality of ultrasound modes,

the apparatus comprising:

an array of ultrasound transducer elements;

imaging circuitry configured to perform ultrasound imaging with the array of ultrasound transducer elements in a first mode;

a pulser configured to provide a voltage to an ultrasound transducer element of the array of ultrasound transducer elements in a second mode, wherein the array generates continuous wave ultrasound or quasi-continuous wave ultrasound in the second mode;

a switch configured to electrically connect the pulser to the ultrasound transducer of the array for the second mode and to electrically disconnect the pulser from the ultrasound transducer of the array for the first mode, the switch being on a chip, and the pulser being external to the chip such that power dissipation associated with the pulser occurs external to the chip;

additional pulsers having phases spaced with each other; and

additional switches configured to electrically connect the additional pulsers to the array in the second mode and to electrically disconnect the additional pulsers from the array in the first mode.

10. An apparatus with a plurality of ultrasound modes,

the apparatus comprising:

an array of ultrasound transducer elements;

imaging circuitry configured to perform ultrasound imaging with the array of ultrasound transducer elements in a first mode;

a pulser configured to provide a voltage to an ultrasound transducer element of the array of ultrasound transducer elements in a second mode, wherein the array generates continuous wave ultrasound or quasi-continuous wave ultrasound in the second mode; and

a switch configured to electrically connect the pulser to the ultrasound transducer of the array for the second mode and to electrically disconnect the pulser from the ultrasound transducer of the array for the first mode, the switch being on a chip, and the pulser being external to the chip such that power dissipation associated with the pulser occurs external to the chip, wherein the pulser has a fixed connection with the switch.

11. The apparatus of claim 10 , further comprising additional switches, wherein the switch and the additional switches are included in a plurality of switches, and wherein each of the ultrasound transducer elements of the array is connected to one switch of the plurality of switches.

12. An apparatus with a plurality of ultrasound modes, the apparatus comprising:

an array of ultrasound transducer elements;

first electronic circuitry configured to drive an ultrasound transducer of the array in a first mode;

second electronic circuitry comprising a pulser configured to drive the ultrasound transducer of the array in a second mode; and

mode switching circuitry configured to connect the pulser to the ultrasound transducer of the array for the second mode and to disconnect the pulser from the ultrasound transducer of the array for the first mode, the mode switching circuitry comprising transistors arranged to pass a voltage from the pulser that is greater than a gate-to-source voltage of any one of the transistors.

13. The apparatus of claim 12 , wherein the array of ultrasound transducer elements is on a transducer chip, the first electronic circuitry is on a chip that is integrated with the transducer chip, and the pulser is external to the chip.

14. The apparatus of claim 13 , wherein the mode switching circuitry is on the chip.

15. The apparatus of claim 12 , wherein the ultrasound transducer elements are capacitive micromachined ultrasonic transducers.

16. The apparatus of claim 12 , wherein the array generates continuous wave ultrasound or quasi-continuous wave ultrasound in the second mode.

17. The apparatus of claim 12 , further comprising a line switch configured to connect the mode switching circuitry to a selected one of a plurality of pulsers having distinct phases, wherein the plurality of pulsers comprise the pulser.

18. A method of operating an array of ultrasound transducers in different modes, the method comprising:

performing ultrasound imaging with an imaging circuit and the array of ultrasound transducers in a first mode;

connecting a pulser to an ultrasound transducer of the array of ultrasound transducers for a second mode using a switch, wherein the pulser is disconnected from the ultrasound transducer of the array for the first mode, and wherein the pulser is external to a chip that includes the switch, and wherein the switch comprises transistors arranged to pass a voltage that is greater than a gate-to-source voltage of any one of the transistors; and

generating, using the array of the ultrasound transducers, a continuous wave of ultrasound or a quasi-continuous wave of ultrasound in the second mode.

19. The method of claim 18 , further comprising adjusting a beam transmitted from the array of ultrasound transducers for the second mode.

20. The method of claim 18 , wherein the ultrasound transducer elements are capacitive micromachined ultrasonic transducers.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 23, 2023
From: BHUYAN, ANSHUMAN; CHOE, JUNG WOO; NIKOOZADEH, AMIN; KHURI-YAKUB, BUTRUS T.
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 063728/0271 →
Continuity (4)
Continuation 16150044 · Oct 2, 2018
Continuation 14793280 · Jul 7, 2015
Provisional Application 62021341 · Jul 7, 2014
Related Publication 20220054109A1 · Feb 24, 2022