Granted Patent B2

US 12,527,761 · App. 17/414,382 · Granted Jan 20, 2026

Inventors: Carine Blanchard (Le Mont-sur-Lausanne, CH); Bernard Cuenoud (Cully, CH); Frederic Destaillats (Servion, CH); Elizabeth Forbes-Blom (Epalinges, CH); Heiko Oertling (Lausanne, CH); Amaury Patin (Lausanne, CH)

Assignee: Societe des Produits Nestle S.A.

A61K31/225C11C3/10

Abstract

Claims (22)

1 . A composition comprising a compound having a formula (1), a compound having a formula (2), a compound having a formula (3) and a compound having a formula (4), wherein the compounds having the formulas (1), (2), (3) and (4) comprise at least 50% by weight of the total triglycerides in the composition,

wherein n1, n2, n3, n4, n5 and n6 are independently 4 to 10.

2 . The composition according to claim 1 comprising a compound having a formula (5), a compound having the formula (6), a compound having the formula (7) and a compound having the formula (8),

wherein the compounds having the formulas (5), (6), (7) and (8) comprise at least 50% by weight of the total triglycerides in the composition.

3 . The composition according to claim 1 , wherein the composition does not contain tributyrin.

4 . A method for use in increasing blood ketone levels, and/or treating a disease treatable by increasing blood ketone levels, comprising administering to an individual in need of same a composition comprising a compound having a formula (1), a compound having a formula (2), a compound having a formula (3) and a compound having a formula (4), wherein the compounds having the formulas (1), (2), (3) and (4) comprise at least 50% by weight of total triglycerides in the composition,

wherein n1, n2, n3, n4, n5 and n6 are independently 4 to 10.

5 . A medicament comprising a compound having a formula (1), a compound having the formula (2), a compound having the formula (3) and a compound having the formula (4), wherein the compounds having the formulas (1), (2), (3) and (4) comprise at least 50% by weight of the total triglycerides in the medicament,

wherein n1=6, n2=6, n3=6, n4=6, n5=6, and n6=6.

6 . The method according to claim 4 , wherein the composition does not contain tributyrin.

7 . The method according to claim 4 , wherein the method comprises administering to an individual in need of same a composition comprising a compound having a formula (5), a compound having the formula (6), a compound having the formula (7) and a compound having the formula (8),

wherein the compounds having the formulas (5), (6), (7) and (8) comprise at least 50% by weight of the total triglycerides in the composition.

8 . The medicament according to claim 5 , wherein the medicament does not contain tributyrin.

9 . The medicament according to claim 5 comprising a compound having a formula (5), a compound having the formula (6), a compound having the formula (7) and a compound having the formula (8),

wherein the compounds having the formulas (5), (6), (7) and (8) comprise at least 50% by weight of the total triglycerides in the medicament.

10 . The composition according to claim 1 , wherein the composition has does not contain tributyrin.

11 . The method according to claim 4 , wherein the composition is administered enterally.

12 . The method according to claim 4 , wherein the composition is administered orally.

13 . The composition according to claim 1 , wherein the compound having formula (1) comprises 2 to 35% by weight of the total triglycerides of the composition.

14 . The method according to claim 4 , wherein the compound having formula (1) comprises 2 to 35% by weight of the total triglycerides of the composition.

15 . The medicament according to claim 5 , wherein the compound having formula (1) comprises 2 to 35% by weight of the total triglycerides of the medicament.

16 . The composition according to claim 2 , wherein the compound having formula (5) comprises 5 to 35% by weight of the total triglycerides of the composition.

Assignments (2)

Priority Claims (1)

Continuity (1)

References Cited (25)