IP Library Granted Patent US 12,589,259
Granted Patent B2
US 12,589,259 · App. 17/431,466 · Granted Mar 31, 2026

Method to optimally splitting arcs in modulated arc therapy (MAT) plans

Inventors: Vaitheeswaran Ranganathan (Bangalore, IN); Natarajan Ramar (Bangalore, IN); Bojarajan Perumal (Bangalore, IN)
Assignee: Elekta, Inc.
A61N5/1031A61N5/1047
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Quick Facts
Patent No.
US 12,589,259
App. No.
17/431,466
Granted
Mar 31, 2026
Kind
B2
Abstract

A non-transitory computer readable medium ( 26 ) stores instructions executable by at least one electronic processor ( 20 ) to perform a method ( 100, 200 ) of identifying possible arc segments for removal in a modulated arc therapy plan. The method includes: iteratively optimizing a modulated arc therapy plan for an initial arc segment; and computing a geometric freedom (GF) metric for each control point (CP) of the initial arc segment.

Claims (64)

1 . A non-transitory computer readable medium storing instructions executable by at least one electronic processor to perform a method of identifying possible arc segments for removal in a modulated arc therapy plan, the method comprising:

iteratively optimizing a modulated arc therapy plan for an initial arc segment; and

computing respective geometric freedom (GF) metrics for each control point (CP) of the initial arc segment, wherein an individual GF metric indicates whether a specified nominal dose of radiation can pass through target voxels associated with a corresponding CP without passing through an identified critical organ voxel.

2 . The non-transitory computer readable medium of claim 1 , wherein the method further includes:

plotting, on a display device, a graph of the GF metric as a function of each CP along the initial arc segment.

3 . The non-transitory computer readable medium of claim 1 , wherein the GF metric is computed for each CP of the initial arc segment based on geometrical contours of a patient and a position of the CP but not based on the modulated arc therapy plan.

4 . The non-transitory computer readable medium of claim 1 , wherein computing a GF metric for each CP of the initial arc segment includes:

computing GF values, an individual GF value including a ratio, for each beam let of the CP, of a number of tumor voxels touched by a beamlet divided by a sum of a number of voxels of critical organs touched by the beamlet;

summing the GF values for the beamlets of the CP to generate the GF metric for the CP.

5 . The non-transitory computer readable medium of claim 4 , wherein the computing of the ratio further includes:

weighting at least one of (i) the number of tumor voxels touched by the beamlet, and (ii) a number of voxels of critical organs touched by the beamlet.

6 . The non-transitory computer readable medium of claim 1 , further including:

plotting, on a display device, at least one of a tumor dose per CP and a critical organ dose per CP from the modulated arc therapy plan.

7 . The non-transitory computer readable medium of claim 1 , further including:

determining GF metric values as a function of CP on a graph being below a preselected threshold; and

determining contiguous groups of CPs with GF metric values below the preselected threshold as candidate arc segments for removal from the modulated arc therapy plan.

8 . The non-transitory computer readable medium of claim 7 , wherein determining contiguous groups of CPs with GF metric values below the preselected threshold as candidate arc segments for removal from the modulated arc therapy plan further includes:

estimating a re-distribution of a dose of the modulated arc therapy plan with the candidate arc segments removed from the modulated arc therapy plan.

9 . The non-transitory computer readable medium of claim 8 , further including:

estimating the re-distribution of the dose of the modulated arc therapy plan delivered by the candidate arc segments relative to remaining arc segments.

10 . The non-transitory computer readable medium of claim 9 , wherein the estimating includes:

scaling the candidate arc segments to the remaining arc segments by the GF metric values of each of the remaining arc segments.

11 . The non-transitory computer readable medium of claim 8 , further including:

plotting, on a display device, the re-distribution of the dose of the modulated arc therapy plan.

12 . The non-transitory computer readable medium of claim 7 , further including:

estimating dose objectives of the modulated arc therapy plan with the GF metrics of each CP and an initial modulated arc therapy plan; and

re-estimating the dose objectives when below a preselected threshold by adjusting a size of at least one of the candidate arc segments until the dose objectives are no longer below the preselected threshold.

13 . The non-transitory computer readable medium of claim 7 , wherein the optimizing comprises:

performing an iterative dose optimization for the are without the candidate arc segments being removed.

14 . A system for identifying possible are segments for removal in a modulated arc therapy plan, the system comprising:

at least one electronic processor programmed to:

iteratively optimize a modulated arc therapy plan for an initial arc segment;

compute respective geometric freedom (GF) metrics for each control point (CP) of the initial arc segment, wherein an individual GF metric indicates whether a specified nominal dose of radiation can pass through target voxels associated with a corresponding CP without passing through an identified critical organ voxel; and

determine contiguous groups of CPs with GF metric values below a pre-selected threshold as candidate arc segments for removal from the modulated arc therapy plan.

15 . The system of claim 14 , further including a display device; and wherein the at least one electronic processor is programmed to:

plot, on the display device, a graph of the GF metric as a function of each CP along the initial arc segment;

determine GF metric values as a function of CP on the graph being below the pre-selected threshold; and

determine contiguous groups of CPs with GF metric values below the pre-selected threshold as candidate arc segments for removal from the modulated arc therapy plan.

16 . The system of claim 14 , wherein the at least one electronic processor is programmed to determine the contiguous groups of CPs with GF metric values below the pre-selected threshold as candidate arc segments for removal from the modulated arc therapy plan by:

estimating a re-distribution of a dose of the modulated arc therapy plan with the candidate arc segments removed from the modulated arc therapy plan.

17 . The system of claim 16 , wherein the at least one electronic processor is programmed to:

estimate the re-distribution of the dose of the modulated arc therapy plan delivered by the candidate arc segments relative to remaining are segments.

18 . The system of claim 17 , wherein the at least one electronic processor is programmed to:

scale the candidate arc segments to the remaining arc segments by the GF metric values of each of the remaining arc segments.

19 . The system of claim 18 , wherein the at least one electronic processor is programmed to:

plot, on a display device, the re-distribution of the dose of the modulated arc therapy plan.

20 . The system of claim 14 , wherein the at least one electronic processor is programmed to:

estimate dose objectives of the modulated arc therapy plan with the GF metrics of each CP and an initial modulated arc therapy plan; and

re-estimate the dose objectives when below a preselected threshold by adjusting a size of at least one of the candidate arc segments until the dose objectives are no longer below the preselected threshold.

21 . A method of identifying possible arc segments for removal in a modulated arc therapy plan, the method comprising:

iteratively optimizing a modulated arc therapy plan for an initial arc segment;

computing a geometric freedom (GF) metric for each control point (CP) of the initial arc segment by operations including:

computing a ratio, for each beamlet of the CP, of a number of tumor voxels touched by a beamlet divided by a sum of a number of voxels of critical organs touched by the beamlet;

summing the GF metric values for the beamlets of the CP to generate the GF metric for the CP;

determining contiguous groups of CPs with GF metric values below a pre-selected threshold as candidate arc segments for removal from the modulated arc therapy plan; and

estimating a re-distribution of a dose of the modulated arc therapy plan with the candidate arc segments removed from the modulated arc therapy plan.

22 . The method of claim 21 , further including:

plotting, on a display device, a graph of the GF metric as a function of each CP along the initial arc segment;

determining GF metric values as a function of CP on the graph being below a preselected threshold;

determining contiguous groups of CPs with GF metric values below the pre-selected threshold as candidate arc segments for removal from the modulated arc therapy plan; and

estimating a re-distribution of a dose of the modulated arc therapy plan with the candidate arc segments removed from the modulated arc therapy plan.

23 . The method of claim 21 , further including:

estimating dose objectives of the modulated arc therapy plan with the GF metrics of each CP and an initial modulated arc therapy plan; and

re-estimating the dose objectives when below a preselected threshold by adjusting a size of at least one of the candidate arc segments until the dose objectives are no longer below the preselected threshold.

Assignments (3)
LICENSE Recorded Jun 28, 2024
From: ELEKTA INC.
To: KONINKLIJKE PHILIPS N.V.
Reel/Frame 068334/0143 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 26, 2024
From: KONINKLIJKE PHILIPS N.V.
To: ELEKTA INC.
Reel/Frame 068055/0471 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 17, 2021
From: RANGANATHAN, VAITHEESWARAN; RAMAR, NATARAJAN; PERUMAL, BOJARAJAN
To: KONINKLIJKE PHILIPS N.V.
Reel/Frame 057197/0932 →
Continuity (2)
Provisional Application 62808394 · Feb 21, 2019
Related Publication 20220118283A1 · Apr 21, 2022
References Cited (16)
US 20140357931A1 · Cheng · 2014 [cited by applicant]
US 20180085596A1 · Peltola · 2018 [cited by examiner]
WO 2011042819A1 · 2011 [cited by applicant]
WO 2017156419A1 · 2017 [cited by applicant]
WO 2018083072A1 · 2018 [cited by applicant]
WO 2020003026A1 · 2020 [cited by applicant]
WO 2020169787 · 2020 [cited by applicant]
International Search Report and Written Opinion of PCT/EP2020/054591, dated Apr. 23, 2020. [cited by applicant]
Rana, Suresh et al “Feasibility of the partial-single arc technique in RapidArc planning for prostate cancer treatment.” Chinese Journal of Cancer, vol. 32, No. 10 (2013) pp. 546-552. [cited by applicant]
Pursley, Jennifer et al “A Comparative Study of Standard Intensity-Modulated radiotherapy and RapidArc Planning Techniques for Ipsilateral and Bilateral head and Neck Irradiation”, Medical Dosimetry, vol. 42, 2017, pp. … [cited by applicant]
Wala, Jeremiah et al “Optimal partial-arcs in VMAT treatment planning.” Physics in Medicine & Biology, vol. 57, No. 18 (2012). [cited by applicant]
Tian, Zhen et al “Multi-GPU Implementation of a VMAT Treatment Plan Optimization Algorithm”, Medical Physics, 2015. [cited by applicant]
Zwan, Benjamin J. et al “The Dosimetric Impact of Control Point Spacing for Sliding Gap MLC Fields”, Journal of Applied Clinicla Medical Physics, vol. 17, No. 6, 2016. [cited by applicant]
Keshet, O. et al.“Semi-Automatic Method to Select Partial Arcs for Segment Modulated Arc Therapy Planning”, I.J. Radiation Oncology, Biology Physics, vol. 75, No. 3, 2009. [cited by applicant]
Rapidarc, Radiotherapy and Radiosurgery, Varian Medical Systems, 2012. [cited by applicant]
“International Application Serial No. PCT EP2020 054591, International Preliminary Report on Patentability mailed Sep. 2, 2021”, 8 pgs. [cited by applicant]