IP Library › Granted Patent US 12,397,153
Granted Patent B2
US 12,397,153 · App. 17/447,110 · Granted Aug 26, 2025

Medical device for sensing and or stimulating tissue

Inventors: Nicholas Lachlan Opie (Parkville, AU); Thomas James Oxley (New York, NY); Gil Simon Rind (Parkville, AU); Stephen Michael Ronayne (Parkville, AU); Sam Emmanuel John (Parkville, AU); Clive N. May (Parkville, AU); David B. Grayden (Parkville, AU)
Assignee: The University of Melbourne
A61N1/0531A61B5/293A61F2/91A61F2/92A61B2018/00214A61B2018/00267A61F2250/0001A61F2250/0002A61N1/0534A61N1/0539
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Quick Facts
Patent No.
US 12,397,153
App. No.
17/447,110
Granted
Aug 26, 2025
Kind
B2
Abstract

Devices, methods and systems for transmitting signals through a device located in a blood vessel of an animal, for stimulating and/or sensing activity of media proximal to the device, wherein the media includes tissue and/or fluid.

Claims (32)

1. A medical device for delivery from a tubular body, the medical device comprising:

a frame structure moveable between a reduced profile and an expanded profile in which a diameter of the frame structure increases;

a plurality of struts formed by the frame structure, wherein the plurality of struts comprises an electrically conductive material that extends along the strut and being covered with a non-conductive material; and

wherein one or more portions of the electrically conductive material is exposed at a first portion of an external surface of one or more of the plurality of struts to form at least one electrode, wherein the non-conductive material covers a second portion of the external surface of one or more of the plurality of struts, wherein the second portion and the first portion are spaced apart radially at a cross section of the at least one electrode.

2. The medical device of claim 1 , further comprising a lead extending away from the frame structure, wherein the electrically conductive material extends along the strut to electrically couple with the lead, and wherein a proximal end of the lead is electrically coupleable to an implantable control unit.

3. The medical device of claim 2 , further comprising a connector block configured to electrically couple the medical device to an external device, where the lead extends from the frame structure to the connector block.

4. The medical device of claim 1 , wherein the at least one electrode has an electrode surface configured to conform to a shape of a vessel wall within the tubular body.

5. The medical device of claim 1 , further comprising a stent shaft coupled to the frame structure, wherein the stent shaft is configured to assist positioning of the frame structure within the tubular body.

6. The medical device of claim 1 , wherein the non-conductive material partially embeds the electrically conductive material.

7. The medical device of claim 6 , where the non-conductive material of at least one of the plurality of struts completely covers the electrically conductive material.

8. The medical device of claim 6 , where the frame structure further comprises a support material in contact with the non-conductive material.

9. The medical device of claim 8 , where non-conductive material is tubular shaped or c-shaped at a cross-section of the strut.

10. The medical device of claim 1 , wherein the at least one electrode comprises a plurality of electrodes.

11. The medical device of claim 10 , where the plurality of electrodes are aligned in a linear pattern on the frame structure selected from the group consisting of a linear pattern, a sinusoidal pattern, and a circumferential pattern.

12. The medical device of claim 1 , wherein the at least one electrode comprises a greater surface area than an adjacent region of the strut.

13. The medical device of claim 1 , where the at least one strut comprises a first strut and further comprising a second strut forming the frame structure, where the second strut comprises a conductive material and a non-conductive material wrapping partially around the conductive material, where the conductive material of the first strut is electrically isolated from the conductive material of the second strut; and

at least a second electrode formed by an opening in the non-conductive material on the second strut.

14. The medical device of claim 1 , further comprising at least one reinforced strut having a support material having a width or thickness greater than at least a second strut, the reinforced strut extending along a length of the frame structure.

15. The medical device of claim 1 , further comprising at least one reinforced strut having a support material having a width or thickness greater than at least a second strut.

16. The medical device of claim 15 , where the reinforced strut extends along a length of the frame structure.

17. The medical device of claim 1 , wherein a cross link between adjoining struts terminates in an apex, where the electrode is located on the apex to enhance apposition between the electrode and the tubular body.

18. The medical device of claim 1 , further comprising a control unit configured to generate a signal that controls an external apparatus, wherein electrical activity transmits from the plurality of electrodes to the control unit.

19. The medical device of claim 18 , wherein the control unit is configured to wirelessly communicate with the external apparatus.

20. The medical device of claim 18 , wherein the external apparatus comprises one or more of an exoskeleton, a prosthetic limb, a wheelchair, a computer, and an electrical or electro-mechanical device.

21. A medical device for delivery from a tubular body, the medical device comprising:

a structure;

at least one strut formed by the structure, wherein the at least one strut comprises an integrated conductive layer extending throughout the structure; and

wherein the at least one strut comprises at least one electrode formed by exposing a first portion the integrated conductive layer, wherein the at least one electrode is not affected during movement of the structure when implanted, wherein the first portion is spaced apart radially from a second portion at a cross section of the at least one electrode, wherein the second portion is covered by a non-conductive material.

22. A medical device for delivery from a tubular body, the medical device comprising:

a frame structure moveable between a reduced profile and an expanded profile in which a diameter of the frame structure increases;

a plurality of struts formed by the frame structure, wherein the plurality of struts comprises an integrated conductive layer extending throughout the frame structure; and

wherein at least one of the plurality of struts comprises at least one electrode formed by exposing the integrated conductive layer, wherein the at least one electrode is located at a cross link between joining struts such that an integrity of the at least one electrode is not affected during movement of the frame structure between the reduced profile and the expanded profile.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 8, 2021
From: OPIE, NICHOLAS L.; OXLEY, THOMAS J.; RIND, GIL S.; RONAYNE, STEPHEN; JOHN, SAM E.; MAY, CLIVE N.; GRAYDEN, DAVID
To: THE UNIVERSITY OF MELBOURNE
Reel/Frame 057413/0268 →
Priority Claims (2)
AU 2015904302 · Oct 20, 2015 · national
AU 2015905045 · Dec 4, 2015 · national
Continuity (5)
Continuation 16539357 · Aug 13, 2019
Continuation 15957574 · Apr 19, 2018
Continuation PCTUS2016057768 · Oct 19, 2016
Provisional Application 62379625 · Aug 25, 2016
Related Publication 20210393948A1 · Dec 23, 2021
References Cited (134)
US 6018682A · Rise · 2000 [cited by applicant]
US 6171239B1 · Humphrey · 2001 [cited by applicant]
US 6442413B1 · Silver · 2002 [cited by applicant]
US 6537310B1 · Palmaz et al. · 2003 [cited by applicant]
US 6820676B2 · Palmaz et al. · 2004 [cited by applicant]
US 7190998B2 · Shalev et al. · 2007 [cited by applicant]
US 7647097B2 · Flaherty et al. · 2010 [cited by applicant]
US 7751877B2 · Flaherty et al. · 2010 [cited by applicant]
US 7881780B2 · Flaherty · 2011 [cited by applicant]
US 7901368B2 · Flaherty et al. · 2011 [cited by applicant]
US 7991461B2 · Flaherty et al. · 2011 [cited by applicant]
US 8060194B2 · Flaherty · 2011 [cited by applicant]
US 8095209B2 · Flaherty · 2012 [cited by applicant]
US 8386050B2 · Donoghue et al. · 2013 [cited by applicant]
US 8560041B2 · Flaherty et al. · 2013 [cited by applicant]
US 8812096B2 · Flaherty et al. · 2014 [cited by applicant]
US 9220899B2 · Cattaneo et al. · 2015 [cited by applicant]
US 9375330B2 · Sims et al. · 2016 [cited by applicant]
US 9821154B2 · Muessig et al. · 2017 [cited by applicant]
US 10485968B2 · Opie et al. · 2019 [cited by applicant]
US 10575783B2 · Oxley · 2020 [cited by applicant]
US 10729530B2 · Opie et al. · 2020 [cited by applicant]
US 11141584B2 · Opie et al. · 2021 [cited by applicant]
US 20040249302A1 · Donoghue et al. · 2004 [cited by applicant]
US 20050113744A1 · Donoghue et al. · 2005 [cited by applicant]
US 20050137646A1 · Wallace et al. · 2005 [cited by applicant]
US 20050137647A1 · Wallace et al. · 2005 [cited by applicant]
US 20050143589A1 · Donoghue et al. · 2005 [cited by applicant]
US 20050203366A1 · Donoghue et al. · 2005 [cited by applicant]
US 20050251238A1 · Wallace · 2005 [cited by examiner]
US 20050251239A1 · Wallace et al. · 2005 [cited by applicant]
US 20050267597A1 · Flaherty et al. · 2005 [cited by applicant]
US 20050272974A1 · Gavriel · 2005 [cited by applicant]
US 20050273890A1 · Flaherty et al. · 2005 [cited by applicant]
US 20060049957A1 · Surgenor et al. · 2006 [cited by applicant]
US 20060058627A1 · Flaherty et al. · 2006 [cited by applicant]
US 20060058854A1 · Abrams et al. · 2006 [cited by applicant]
US 20060089709A1 · Helmus · 2006 [cited by applicant]
US 20060167564A1 · Flaherty et al. · 2006 [cited by applicant]
US 20060189901A1 · Flaherty et al. · 2006 [cited by applicant]
US 20060206167A1 · Flaherty et al. · 2006 [cited by applicant]
US 20060241356A1 · Flaherty · 2006 [cited by applicant]
US 20060253166A1 · Flaherty et al. · 2006 [cited by applicant]
US 20060259107A1 · Caparso et al. · 2006 [cited by applicant]
US 20070032738A1 · Flaherty et al. · 2007 [cited by applicant]
US 20070106143A1 · Flaherty · 2007 [cited by applicant]
US 20070142871A1 · Libbus et al. · 2007 [cited by applicant]
US 20070156126A1 · Flaherty · 2007 [cited by applicant]
US 20070239256A1 · Weber et al. · 2007 [cited by applicant]
US 20080009914A1 · Buysman et al. · 2008 [cited by applicant]
US 20080015459A1 · Llinas · 2008 [cited by applicant]
US 20080027346A1 · Litt et al. · 2008 [cited by applicant]
US 20080118546A1 · Thatcher et al. · 2008 [cited by applicant]
US 20080119911A1 · Rosero · 2008 [cited by applicant]
US 20080183253A1 · Bly · 2008 [cited by applicant]
US 20090131873A1 · Spear et al. · 2009 [cited by applicant]
US 20090155336A1 · Rezai · 2009 [cited by applicant]
US 20090221896A1 · Rickert et al. · 2009 [cited by applicant]
US 20100023021A1 · Flaherty · 2010 [cited by applicant]
US 20100063411A1 · Donoghue et al. · 2010 [cited by applicant]
US 20100106259A1 · Llinas et al. · 2010 [cited by applicant]
US 20100114195A1 · Burnes et al. · 2010 [cited by applicant]
US 20100152812A1 · Flaherty et al. · 2010 [cited by applicant]
US 20100292602A1 · Worrell et al. · 2010 [cited by applicant]
US 20100305476A1 · Thornton et al. · 2010 [cited by applicant]
US 20130090651A1 · Smith · 2013 [cited by applicant]
US 20130096648A1 · Benson · 2013 [cited by applicant]
US 20130206454A1 · Cattaneo et al. · 2013 [cited by applicant]
US 20130226272A1 · Cattaneo et al. · 2013 [cited by applicant]
US 20130231658A1 · Wang et al. · 2013 [cited by applicant]
US 20130282084A1 · Mathur et al. · 2013 [cited by applicant]
US 20140025069A1 · Willard · 2014 [cited by examiner]
US 20140058528A1 · Contreras-Vidal et al. · 2014 [cited by applicant]
US 20140142570A1 · Bakczewitz et al. · 2014 [cited by applicant]
US 20140180391A1 · Dagan et al. · 2014 [cited by applicant]
US 20140288667A1 · Oxley · 2014 [cited by applicant]
US 20150105772A1 · Hill et al. · 2015 [cited by applicant]
US 20150230742A1 · Silver · 2015 [cited by applicant]
US 20180236221A1 · Opie et al. · 2018 [cited by applicant]
US 20180303595A1 · Opie et al. · 2018 [cited by applicant]
US 20190046119A1 · Oxley · 2019 [cited by applicant]
US 20190358445A1 · Opie et al. · 2019 [cited by applicant]
US 20200352697A1 · Opie et al. · 2020 [cited by applicant]
US 20210378595A1 · Oxley · 2021 [cited by applicant]
US 20240099825A1 · Opie et al. · 2024 [cited by applicant]
US 20240207034A1 · Opie et al. · 2024 [cited by applicant]
CN 101052343 · 2007 [cited by applicant]
CN 101137977 · 2008 [cited by applicant]
JP 1998340747 · 1998 [cited by applicant]
JP 2007520254 · 2007 [cited by applicant]
JP 2007535984 · 2007 [cited by applicant]
JP 2008538517 · 2008 [cited by applicant]
JP 2009519807 · 2009 [cited by applicant]
JP 2009527303 · 2009 [cited by applicant]
JP 2009531157 · 2009 [cited by applicant]
JP 2010516384 · 2010 [cited by applicant]
JP 2010516405 · 2010 [cited by applicant]
JP 2013514860 · 2013 [cited by applicant]
JP 2013157275 · 2013 [cited by applicant]
JP 2016202820 · 2016 [cited by applicant]
JP 2019514444 · 2019 [cited by applicant]
WO WO2003101532 · 2003 [cited by applicant]
WO WO2005001707 · 2005 [cited by applicant]
WO WO2005046469 · 2005 [cited by applicant]
WO WO2005051167 · 2005 [cited by applicant]
WO WO2005051189 · 2005 [cited by applicant]
WO WO2005065738 · 2005 [cited by applicant]
WO WO2005092183 · 2005 [cited by applicant]
WO WO2005107852 · 2005 [cited by applicant]
WO WO2005110528 · 2005 [cited by applicant]
WO WO2006015002 · 2006 [cited by applicant]
WO WO2006020794 · 2006 [cited by applicant]
WO WO2006041738 · 2006 [cited by applicant]
WO WO2006073915 · 2006 [cited by applicant]
WO WO2006074029 · 2006 [cited by applicant]
WO WO2006076164 · 2006 [cited by applicant]
WO WO2006076175 · 2006 [cited by applicant]
WO WO2006078432 · 2006 [cited by applicant]
WO WO2006086086 · 2006 [cited by applicant]
WO WO2006105478 · 2006 [cited by applicant]
WO WO2007058950 · 2007 [cited by applicant]
WO WO2007078410 · 2007 [cited by applicant]
WO WO2007146060 · 2007 [cited by applicant]
WO WO2008019384 · 2008 [cited by applicant]
WO WO2008094345 · 2008 [cited by applicant]
WO WO2008094789 · 2008 [cited by applicant]
WO WO2009135075 · 2009 [cited by applicant]
WO WO2010078175 · 2010 [cited by applicant]
WO WO2013049887 · 2013 [cited by applicant]
WO WO2017070252 · 2017 [cited by applicant]
WO WO2018195083 · 2018 [cited by applicant]
U.S. Appl. No. 16/539,357, filed Aug. 13, 2019. [cited by applicant]
U.S. Appl. No. 15/957,574, filed Apr. 19, 2018. [cited by applicant]
Oxley, T. et al. “Minimally invasive endovascular stent-electrode array for high-fidelity, chronic recordings of cortical neural activity,” [cited by applicant]