Anti-inflammatory botanical extract
A botanical extract that exhibits anti-inflammatory activity, wherein the botanical extract is at least an extract from the leaf of Vaccinium macrocarpon.
1. A composition comprising:
a botanical extract of a leaf of Vaccinium macrocarpon,
wherein the botanical extract is present in an amount of about 50.0 μg/mL to about 500.0 μg/mL,
wherein the botanical extract comprises at least isoquercetin and kaempferol and is free of anthocyanins,
wherein the extract is obtained by extracting dried ground cranberry leaf powder with a solvent of ethanol in water and evaporating the solvent,
a pharmaceutically acceptable carrier,
wherein the composition exhibits anti-inflammatory activity.
2. The composition according to claim 1 , wherein the composition inhibits COX-1 activity.
3. The composition according to claim 1 , wherein the composition inhibits COX-2 activity.
4. The composition according to claim 1 , wherein the composition inhibits 5-LOX activity.
5. The composition according to claim 1 , wherein the composition inhibits COX-1 activity, COX-2 activity, and 5-LOX activity.
6. The composition according to claim 1 , wherein the composition is a dietary supplement.
7. The dietary supplement according to claim 1 , wherein the composition is a topical composition.