IP Library Granted Patent US 11,719,631
Granted Patent B2
US 11,719,631 · App. 17/477,528 · Granted Aug 8, 2023

Measuring light scattering of a sample

Inventors: Dwight Kahng (Camarillo, CA); Cha Lee (Santa Barbara, CA); Sigrid C. Kuebler (Old Orchard Beach, ME); Ross E. Bryant (Cape Elizabeth, ME)
Assignee: WYATT TECHNOLOGY CORPORATION
G01N21/47G06F3/04847G01N2201/126
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Quick Facts
Patent No.
US 11,719,631
App. No.
17/477,528
Granted
Aug 8, 2023
Kind
B2
Abstract

The present disclosure describes a computer implemented method, a system, and a computer program product of measuring light scattering of a sample.

Claims (47)

1. A computer implemented method comprising:

displaying, by a computer system, at least one graphic,

wherein the at least one graphic is one of an alarms graphic, a size graphic, a molar mass graphic, a presets graphic, an experiments graphic, and a settings graphic, on a display logically coupled to a light scattering measurement instrument, thereby resulting in a graphics page,

wherein the instrument is configured to measure at least one of dynamic light scattering, static light scattering, and electrophoretic light scattering, of at least one sample, resulting in a light scattering measurement;

in response to receiving, by the computer system, a selection command corresponding to the alarms graphic, displaying, by the computer system, on the display an alarms page;

in response to receiving, by the computer system, a selection command corresponding to the size graphic, displaying, by the computer system, on the display a size workflow page displaying a guided size workflow,

wherein the guided size workflow comprises size functions corresponding to size parameter commands to direct the instrument to take at least one size measurement in light of entered size parameter commands corresponding to the size functions;

in response to receiving, by the computer system, a selection command corresponding to the molar mass graphic, displaying, by the computer system, on the display a molar mass workflow page displaying a guided molar mass workflow,

wherein the guided molar mass workflow comprises molar mass functions to direct the instrument to take at least one molar mass measurement in light of entered molar mass parameter commands corresponding to the molar mass parameter commands;

in response to receiving, by the computer system, a selection command corresponding to the presets graphic, displaying, by the computer system, on the display a presets page configured to provide access to at least one saved workflow;

in response to receiving, by the computer system, a selection command corresponding to the experiments graphic, displaying, by the computer system, on the display an experiments page configured to display results obtained during at least one saved experiment and configured to provide access to the results; and

in response to receiving, by the computer system, a selection command corresponding to the settings graphic, displaying, by the computer system, on the display a settings page configured to display instrument settings and configured to allow for modifying at least one setting of the instrument.

2. The method of claim 1 wherein the displaying the alarms page comprises

displaying, by the computer system, on the display, at least one of at least one active instrument alarm and at least one historical alarm, corresponding to the measurement.

3. The method of claim 1 wherein the size functions comprise

a cuvette function, a solvent function, a temperature function, a measurements function, and a summary function.

4. The method of claim 1 wherein the size parameter commands comprise a cuvette command, a solvent command, a temperature command, and a measurements command.

5. The method of claim 1 wherein the molar mass functions comprise

a cuvette function, a sample function, a solvent function, a temperature function, a measurements function, and a summary function.

6. The method of claim 1 wherein the molar mass parameter commands comprise a cuvette command, sample command, a solvent command, a temperature command, and a measurements command.

7. The method of claim 1 wherein the results obtained during the at least one saved experiment comprise a workflow and data corresponding to the at least one saved experiment.

8. The method of claim 1 further comprising:

displaying, by the computer system, on the display a progress graphic; and

in response to receiving, by the computer system, a selection command corresponding to the progress graphic, transmitting, by the computer system, a collect command to the instrument to collect data traces, instrument settings, experiment parameters, and instrument usage data for the measurement, resulting in a collection corresponding to the measurement, and to store the data traces, the instrument settings, the experiment parameters, and instrument usage data in a data store.

9. The method of claim 8 wherein the instrument usage data comprise at least one user id corresponding to a user of the instrument.

10. The method of claim 8 further comprising

displaying, by the computer system, on the display, a progress page configured to display an amount of time remaining until the collection is complete.

11. The method of claim 8 further comprising

transmitting, by the computer system, at least one status of the collection to a data sink.

12. The method of claim 10 further comprising

displaying, by the computer system, a results page allowing for at least one of displaying at least one of data and graphs of data of the collection and displaying at least one report of at least one of data and graphs of data of the collection.

13. The method of claim 1 further comprising

executing, by the computer system, a set of logical operations identifying each individual computer system among the plurality of client computer systems, by at least a session ID corresponding to the individual computer system and an IP address corresponding to the individual computer system.

14. The method of claim 3 wherein the summary function is configured to display, by the computer system on the display, at least one of a measurements graphic, a cuvette graphic, a temperature graphic, a solvent graphic, and a post collection graphic.

15. The method of claim 14 further comprising

displaying, by the computer system, on the display a start graphic and a cancel graphic.

16. The method of claim 5 wherein the summary function is configured to display, by the computer system on the display, at least one of a measurements graphic, a cuvette graphic, a temperature graphic, a sample type graphic, a solvent graphic, and a post-collection graphic.

17. The method of claim 16 further comprising

displaying, by the computer system, on the display a start graphic and a cancel graphic.

18. The method of claim 17 wherein in response to receiving, by the computer system, a selection command corresponding to the sample type graphic, executing, by the computer system, a set of logical operations allowing for selecting at least one of a workflow, measurement settings, and data filter settings, for the measurement.

19. The method of claim 1 further comprising

displaying, by the computer system, on the display a data quality graphic; and

in response to receiving, by the computer system, a selection command corresponding to the data quality graphic, displaying, by the computer system on the display, an assessment of results corresponding to the measurement.

20. The method of claim 1 wherein the guided workflow comprises

a workflow guided by a rule set corresponding to an interdependency among parameters of the measurement.

21. The method of claim 1 wherein the displaying further comprises

displaying, by the computer system, at least one of a zeta potential graphic, a molar mass and size graphic, and a zeta potential and size graphic.

Assignments (2)
CHANGE OF NAME Recorded Aug 7, 2023
From: WYATT TECHNOLOGY CORPORATION
To: WYATT TECHNOLOGY, LLC
Reel/Frame 064522/0796 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 16, 2023
From: KAHNG, DWIGHT; LEE, CHA; KUEBLER, SIGRID C.; BRYANT, ROSS E.
To: WYATT TECHNOLOGY CORPORATION
Reel/Frame 063661/0168 →
Continuity (2)
Provisional Application 63079475 · Sep 16, 2020
Related Publication 20220147234A1 · May 12, 2022