Intraocular implants and related kits and methods
Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within Schlemm's canal and that may restore or maintain at least partial patency of the canal without substantially interfering with transmural or transluminal fluid flow across the canal. The devices utilize the natural drainage process of the eye and may be implanted with minimal trauma to the eye. Kits may include a support and an introducer for implanting the support within Schlemm's canal. Methods may include implanting a support within Schlemm's canal, where the support is capable of restoring or maintaining at least partial patency of the canal without substantial interference with transmural or transluminal fluid flow across the canal.
1. A method of reducing intraocular pressure in a patient, the method comprising:
advancing a cutting device to a trabecular meshwork ab interno and creating an opening in the trabecular meshwork with the cutting device;
separately advancing a delivery device comprising an elongated member to the trabecular meshwork ab interno;
advancing the elongated member through the opening in the trabecular meshwork and into Schlemm's canal; and
moving the elongated member within and relative to Schlemm's canal and delivering fluid to Schlemm's canal to dilate Schlemm's canal and reduce intraocular pressure.
2. The method of claim 1 , wherein the elongated member is advanced around an entire circumference of Schlemm's canal.
3. The method of claim 1 , wherein the elongated member is advanced approximately halfway around a circumference of Schlemm's canal.
4. The method of claim 1 , wherein the elongated member comprises rounded edges.
5. The method of claim 1 , wherein the elongated member comprises a tip portion having a rounded end configured to guide the elongated member down Schlemm's canal.
6. The method of claim 1 , wherein the elongated member comprises a coating to minimize trauma to Schlemm's canal.
7. The method of claim 1 , wherein the elongated member is illuminated, and the illumination of the elongated member is used to monitor the position of the elongated member.
8. The method of claim 1 , wherein the elongated member is illuminated, and the illumination of the elongated member is used to monitor the performance of the elongated member.
9. The method of claim 1 , wherein the elongated member is illuminated using a laser or a light emitting diode.
10. The method of claim 1 , wherein the fluid is a viscoelastic fluid.
11. The method of claim 10 , wherein the viscoelastic fluid is sodium hyaluronate.
12. The method of claim 1 , wherein the patient is suffering from glaucoma.
13. The method of claim 1 , wherein the fluid is combined with one or more drugs.
14. The method of claim 13 , wherein the one or more drugs comprise a prostaglandin, beta blocker, miotic, alpha adrenergic agonist, or carbonic anhydrase inhibitor.
15. The method of claim 1 , wherein the elongated member is advanced with a forceps.
16. The method of claim 1 , wherein the elongated member is formed of a wire, a polymer, or a combination thereof.
17. The method of claim 1 , wherein the cutting device comprises a blade.
18. The method of claim 1 , wherein the cutting device comprises a needle.
19. The method of claim 1 , wherein the cutting device is an electrocautery device.
20. The method of claim 1 , wherein the elongated member comprises a diameter of at least about 200 micrometers.
21. The method of claim 1 , wherein the elongated member comprises a diameter of up to about 300 micrometers.
22. The method of claim 1 , wherein the elongate member comprises a diameter of at least about 200 micrometers and up to about 300 micrometers.