COMPOSITIONS AND METHODS FOR THE TREATMENT OF PRESBYOPIA
The invention provides compositions and methods for the treatment of presbyopia. The compositions preferably comprise aceclidine. The compositions optionally contain a surfactant and a viscosity agent.
1 . A method of treating presbyopia comprising administering to a subject in need thereof an ophthalmological composition comprising aceclidine.
2 . The method of claim 1 , wherein aceclidine is at a concentration from about 0.25% to about 2.5% w/v, wherein w/v denotes weight by total volume of the composition.
3 . The method of claim 1 , wherein aceclidine is at a concentration from about 0.75% to about 2.5% w/v.
4 . A method of treating presbyopia comprising administering to a subject in need thereof an ophthalmological composition comprising aceclidine and a viscosity agent.
5 . The method of claim 4 , wherein aceclidine is at a concentration from about 0.25% to about 2.5% w/v, wherein w/v denotes weight by total volume of the composition.
6 . The method of claim 4 , wherein aceclidine is at a concentration from about 0.75% to about 2.5% w/v.
7 . A method of treating presbyopia comprising administering a composition comprising aceclidine and one or more nonionic surfactants to a subject in need thereof.
8 . The method of claim 7 , wherein aceclidine is at a concentration from about 0.25% to about 2.5% w/v, wherein w/v denotes weight by total volume of the composition.
9 . The method of claim 7 , wherein aceclidine is at a concentration from about 0.75% to about 2.5% w/v.
10 . A method of treating low regular astigmatism, low or high irregular astigmatism, keratoconic ectasia, night vision halos/starbursts, night vision reduced contrast, and low myopia, or hyperopia, with or without astigmatism, comprising administering to a subject in need thereof an ophthalmological composition comprising aceclidine.