IP Library › Granted Patent US 12,343,479
Granted Patent B2
US 12,343,479 · App. 17/502,389 · Granted Jul 1, 2025

Neurovascular catheter

Inventors: Yi Yang (San Francisco, CA); Farhad Khosravi (Los Altos Hills, CA); Lisa M. Young (Mountain View, CA)
Assignee: Incept, LLC
A61M25/0053A61B6/481A61B6/501A61B17/12022A61B17/12168A61B17/12186A61B17/22A61B17/2202A61B17/22031A61B17/3203A61B17/32037A61B17/320725A61B17/320758A61F2/95A61F7/12A61L29/02A61L29/041A61L29/06A61L29/14A61M1/32A61M1/743A61M1/80A61M5/007A61M25/0009A61M25/0012A61M25/0023A61M25/0045A61M25/005A61M25/007A61M25/0074A61M25/008A61M25/0082A61M25/0097A61M25/01A61M25/0102A61M25/0108A61M25/0147A61M25/0662A61M25/09A61M25/10A61M25/1027A61M39/06B29C41/14A61B2017/00398A61B2017/00526A61B2017/00734A61B2017/00862A61B2017/00867A61B2017/00898A61B2017/00955A61B17/22012A61B2017/22025A61B2017/22034A61B2017/22038A61B2017/22062A61B2017/22067A61B2017/22079A61B2017/22084A61B2017/320733A61B2017/320775A61B2217/005A61F2007/126A61L2400/10A61L2400/16A61M2025/0002A61M2025/0004A61M2025/0046A61M25/0052A61M2025/0058A61M2025/0059A61M2025/0079A61M2025/0096A61M2025/0175A61M31/005A61M2039/062A61M2205/0216A61M2205/0266A61M2205/3344A61M2210/12B29C41/02B29C41/22B29C41/42B29C63/18B29C63/20B29C63/22B29C66/52B29C66/522B29C66/5221B29K2027/18B29K2075/00B29L2031/7542
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Quick Facts
Patent No.
US 12,343,479
App. No.
17/502,389
Filed
Oct 15, 2021
Granted
Jul 1, 2025
Kind
B2
Art Unit
3783
USPC
604/526
Abstract

A neurovascular catheter is provided, such as for distal neurovascular access or aspiration. The catheter includes an elongate flexible tubular body, having a proximal end, a distal end and a side wall defining a central lumen. The side wall includes a tubular inner liner, a tie layer separated from the central lumen by the inner liner, a helical coil at least partially overlapping the tie layer, and a tubular braid. A first section of adjacent windings of the helical coil can be spaced farther apart from each other than a second section of adjacent windings of the helical coil.

Claims (43)

1. An enhanced flexibility neurovascular catheter comprising:

an elongate flexible body comprising a side wall defining a central lumen, the side wall comprising:

a tubular inner liner;

a tie layer separated from the central lumen by the inner liner;

a helical coil at least partially overlapping the tie layer, the helical coil comprising a plurality of windings, the plurality of windings comprising a first section of adjacent windings and a second section of adjacent windings, the first section of adjacent windings being spaced farther apart from each other than the second section of adjacent windings, the first section of adjacent windings being located in a distal direction relative to the second section of adjacent windings; and

a tubular braid being at least partially located in a proximal direction relative to the helical coil; and

an outer jacket at least partially overlapping the helical coil and the tubular braid, the outer jacket comprising:

a first section comprising a first durometer equal to or less than about 35D, the first section positioned at a distalmost end of the elongate flexible body;

a second section comprising a second durometer of at least about 60D; and

a third section being located between the first section and the second section, the third section comprising a plurality of tubular segments, each tubular segment of the plurality of tubular segments comprising a durometer between the first durometer and the second durometer, a first tubular segment of the plurality of tubular segments being located in a distal direction relative to a second tubular segment of the plurality of tubular segments, the first tubular segment comprising a durometer less than a durometer of the second tubular segment.

2. The enhanced flexibility neurovascular catheter of claim 1 , wherein the plurality of tubular segments of the outer jacket comprises at least five tubular segments.

3. The enhanced flexibility neurovascular catheter of claim 2 , wherein the plurality of tubular segments of the outer jacket comprises at least nine tubular segments.

4. The enhanced flexibility neurovascular catheter of claim 1 , wherein a difference in durometer between a proximal segment of the plurality of tubular segments and a distal segment of the plurality of tubular segments is at least about 20D.

5. The enhanced flexibility neurovascular catheter of claim 4 , wherein the difference in durometer between the proximal segment of the plurality of tubular segments and the distal segment of the plurality of tubular segments is at least about 30D.

6. The enhanced flexibility neurovascular catheter of claim 1 , wherein a winding of a proximal section of the helical coil is spaced about 0.004 inches from an adjacent winding of the proximal section of the helical coil.

7. The enhanced flexibility neurovascular catheter of claim 1 , wherein a winding of a distal section of the helical coil is spaced about 0.006 inches from an adjacent winding of the distal section of the helical coil.

8. The enhanced flexibility neurovascular catheter of claim 1 , wherein a winding of a distal section of the helical coil is spaced about 0.007 inches from an adjacent winding of the distal section of the helical coil.

9. The enhanced flexibility neurovascular catheter of claim 1 , wherein a length of the helical coil is at least about 20% of a length of the elongate flexible body.

10. The enhanced flexibility neurovascular catheter of claim 1 , wherein the side wall of the elongate flexible body further comprises an axial filament proximate to a distal end of the elongate flexible body and extending in the proximal direction.

11. The enhanced flexibility neurovascular catheter of claim 10 , wherein the axial filament comprises a length less than or equal to about 50 cm.

12. The enhanced flexibility neurovascular catheter of claim 10 , wherein the axial filament comprises a length less than or equal to about 40 cm.

13. The enhanced flexibility neurovascular catheter of claim 1 ,

wherein the plurality of tubular segments of the outer jacket comprises at least five tubular segments,

wherein a difference in durometer between a proximal segment of the plurality of tubular segments and a distal segment of the plurality of tubular segments is at least about 20D,

wherein a winding of a proximal section of the helical coil is spaced about 0.004inches from an adjacent winding of the proximal section of the helical coil,

wherein a winding of a distal section of the helical coil is spaced about 0.006 inches from an adjacent winding of the distal section of the helical coil, and

wherein a length of the helical coil is at least about 20% of a length of the elongate flexible body.

14. An enhanced flexibility catheter comprising:

an elongate flexible body comprising a side wall defining a central lumen, the side wall comprising:

a tubular inner liner;

a tie layer separated from the central lumen by the inner liner;

a helical coil at least partially overlapping the tie layer; and

a tubular braid being at least partially located in a proximal direction relative to the helical coil; and

an outer jacket at least partially overlapping the helical coil and the tubular braid;

wherein a flexibility profile of the elongate flexible body is measurable with a three point flexural test with a 1-inch length and 2 mm displacement to determine a flexural load value, and wherein:

a distalmost end of the elongate flexible body comprises a first flexural load value;

a proximal end of the elongate flexible body comprises a second flexural load value greater than the first flexural load value; and

a transition region of the elongate flexible body located between the distalmost end and the proximal end comprises a third flexural load value between the first flexural load value and the second flexural load value.

15. The enhanced flexibility catheter of claim 14 , wherein the helical coil comprises a plurality of windings, the plurality of windings comprising a first section of adjacent windings and a second section of adjacent windings, the first section of adjacent windings being spaced farther apart from each other than the second section of adjacent windings, the first section of adjacent windings being located in a distal direction relative to the second section of adjacent windings.

16. The enhanced flexibility catheter of claim 14 , wherein the third flexural load value at a point about 60 cm from the proximal end of the elongate flexible body is greater than or equal to about 3.5 lbF.

17. The enhanced flexibility catheter of claim 14 , wherein the third flexural load value at a point about 70 cm from the proximal end of the elongate flexible body is less than or equal to about 1.5 lbF.

18. The enhanced flexibility catheter of claim 14 , wherein the third flexural load value at a point about 95 cm from the proximal end of the elongate flexible body is less than or equal to about 0.5 lbF.

19. The enhanced flexibility catheter of claim 14 , wherein the third flexural load value at a point about 115 cm from the proximal end of the elongate flexible body is less than or equal to about 0.3 1bF.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 5, 2022
From: YANG, YI; YOUNG, LISA M.
To: THE STROKE PROJECT, INC.
Reel/Frame 059508/0301 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 5, 2022
From: THE STROKE PROJECT, INC.
To: INCEPT, LLC
Reel/Frame 059508/0342 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 5, 2022
From: KHOSRAVI, FARHAD
To: IMPERATIVE CARE, INC.
Reel/Frame 059508/0373 →
CHANGE OF NAME Recorded Apr 5, 2022
From: THE STROKE PROJECT, INC.
To: IMPERATIVE CARE, INC.
Reel/Frame 059611/0710 →
Continuity (6)
Continuation 16542657 · Aug 16, 2019
Continuation 15443948 · Feb 27, 2017
Continuation 15442393 · Feb 24, 2017
Provisional Application 62443595 · Jan 6, 2017
Provisional Application 62299418 · Feb 24, 2016
Related Publication 20220211975A1 · Jul 7, 2022
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