IP Library › Granted Patent US 12,350,236
Granted Patent B2
US 12,350,236 · App. 17/543,924 · Granted Jul 8, 2025

Multi-chamber bag for parenteral nutrition solutions

Inventors: Freddy Desbrosses (Thuin, BE); Pierpaolo Padula (Etterbeek, BE); Jean-Claude Bezin (Lessines, BE); Marin Demulier (Jumet, BE)
Assignees: Baxter International Inc.; Baxter Healthcare SA
A61J1/2093A61J1/10A61J1/1462A61J1/1475B65B3/003B65B3/02
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Quick Facts
Patent No.
US 12,350,236
App. No.
17/543,924
Granted
Jul 8, 2025
Kind
B2
Abstract

A flexible multi-chamber bag for storing and reconstituting parenteral nutrition solutions is disclosed. The flexible multi-chamber bag comprises two first peelably sealing walls between the two polymer films extending from the top edge to the bottom edge and separating the first bag into a first chamber, a second chamber and a third chamber, wherein the first chamber is between the second chamber and the third chamber; and at least one of the two first peelably sealing walls split into a second plurality of second peelably sealing walls and the second plurality of the second sealing walls sealed to the bottom edge to form a fourth chamber.

Claims (21)

1. A method of manufacturing an “all-in-one” parenteral nutrition system, the method comprising:

producing a flexible multi-chamber bag, the flexible multi-chamber bag comprising:

a first chamber comprising a first port tube;

a second chamber comprising a second port tube;

a third chamber comprising a third port tube;

a fourth chamber comprising a fourth port tube; and

a fifth chamber comprising a fifth port tube,

wherein the first chamber is between the second chamber and the third chamber;

adding an amino acids solution into the first chamber through the first port tube;

adding a glucose solution into the second chamber through the second port tube;

adding a lipid emulsion into the third chamber through the third port tube;

adding a vitamins solution or emulsion into the fourth chamber through the fourth port tube;

adding a trace elements solution into the fifth chamber through the fifth port tube;

sealing the fourth port tube and the fifth port tube by sealing the flexible multi-chamber bag, and

cutting and removing portions of the flexible multi-chamber bag comprising the fourth port tube and the fifth port tube after the sealing to form the “all-in-one” parenteral nutrition system.

2. The method of claim 1 , wherein the “all-in-one” parenteral nutrition system comprises a funnel shape near a bottom edge after the portions of the multi-chamber bag are cut and removed.

3. The method of claim 1 , wherein the first port tube remains in the first portion after the portions of the flexible multi-chamber bag comprising the fourth port tube and the fifth port tube are cut and removed.

4. The method of claim 1 , wherein the producing the multi-chamber bag comprises sealing a top edge, a bottom edge, a left edge, and a right edge with a non-peelable seal.

5. The method of claim 4 , wherein producing the multi-chamber bag further comprises sealing a first wall and a second wall in the flexible multi-chamber bag with a peelable seal, wherein the first wall and the second wall separate the flexible multi-chamber bag into the first chamber, the second chamber, and the third chamber.

6. The method of claim 5 , wherein the first wall splits into a third wall and fourth wall, and wherein the third wall and the fourth wall delimit the fourth chamber.

7. The method of claim 5 , wherein the second wall splits into a fifth wall and sixth wall, and wherein the fifth wall and the sixth wall delimit the fifth chamber.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 3, 2025
From: BAXTER R&D EUROPE SPRL
To: BAXTER INTERNATIONAL INC.; BAXTER HEALTHCARE SA
Reel/Frame 071304/0193 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 3, 2025
From: DESBROSSES, FREDDY; PADULA, PIERPAOLO; BEZIN, JEAN-CLAUDE; DEMULLIER, MARIN
To: BAXTER R&D EUROPE SPRL
Reel/Frame 071304/0260 →
Continuity (1)
Related Publication 20230172809A1 · Jun 8, 2023
References Cited (16)
US 5267646A · Inoue et al. · 1993 [cited by applicant]
US 6039720A · Wieslander · 2000 [cited by examiner]
US 20050194060A1 · Houwaert et al. · 2005 [cited by applicant]
US 20070031976A1 · Trouilly · 2007 [cited by examiner]
US 20090166363A1 · Balteau · 2009 [cited by examiner]
US 20090254032A1 · Muramatsu · 2009 [cited by examiner]
US 20100318058A1 · Schroder · 2010 [cited by examiner]
US 20130039606A1 · Pittet et al. · 2013 [cited by applicant]
US 20130144247A1 · Davenport · 2013 [cited by examiner]
US 20160000652A1 · Uwe-Bernd · 2016 [cited by applicant]
EP 0790051 · 1997 [cited by applicant]
EP 2080501 · 2009 [cited by applicant]
International Search Report for Application No. PCT/US2022/08108 dated Apr. 4, 2023 (4 pages). [cited by applicant]
Vanek et al., A.S.P.E.N. Nutrition in Clinical Practice 2012, 27:440-491. [cited by applicant]
Osland et al., Australasian Society for Parenteral and Enteral Nutrition (AuSPEN) adult vitamin guidelines for parenteral nutrition. Asia Pac J of Clin Nutr 2016, 25(3):636-650. [cited by applicant]
Blaauw et al. Parenteral Provision of Micronutrients to Adult Patients: An Expert Consensus Paper. JPEN J Parenter Enteral Nutr. Mar. 2019;43 Suppl 1:S5-S23. [cited by applicant]
Cited By (1)
US 1,148,133