IP Library Granted Patent US 11,723,384
Granted Patent B2
US 11,723,384 · App. 17/552,184 · Granted Aug 15, 2023

L-amino acid-containing feedstuff additive

Inventors: Ansgar Oelmann (Gelnhausen, DE); Hans Christian Alt (Gelnhausen, DE); Wilfried Blümke (Schöneck, DE); Franz Ulrich Becker (Freigericht-Horbach, DE); Christopher John Conrad (Omaha, NE)
Assignee: Evonik Operations GmbH
A23K20/142A23K10/12A23K20/00A23K20/158A23K40/10A23K40/30
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Quick Facts
Patent No.
US 11,723,384
App. No.
17/552,184
Granted
Aug 15, 2023
Kind
B2
Abstract

Granulated animal feed additives having high bulk density were obtained by adding a surface-active substance to a fermentation broth containing amino acid before spray-drying, wherein low residual moisture levels were achieved at high spray rates and low granulator temperatures.

Claims (34)

1. A method for preparing a feed additive, comprising the following steps:

a) obtaining a fermentation broth by:

i) fermenting an L-amino acid-producing microorganism in an aqueous culture medium to produce a fermentation broth;

ii) after the fermenting step i) is complete: adding surface-active substance to the fermentation broth to a final concentration of 0.025 to 20% by weight; and

b) drying the fermentation broth obtained in step (a) in order to convert it into said feed additive;

wherein the concentrations of biomass and surface-active substance in the fermentation broth are such that the feed additive of step b) is a particulate composition with a particle density of at least 1.138 g/cm 3 .

2. The method of claim 1 , wherein the amount of surface-active substance present prior to drying is sufficient to produce a dried feed additive with a particle density of 1.138 to 1.160 g/cm 3 .

3. The method of claim 1 , wherein, prior to drying, the fermentation broth comprises a surface-active substance selected from the group consisting of: corn steep liquor, lipids, antifoaming agents, surfactants and mixtures thereof.

4. The method of claim 1 , wherein, prior to drying, the fermentation broth comprises an antifoaming agent selected from the group consisting of: polysiloxanes, mono- and polyglycols, phospholipids and fatty acid glycerides.

5. The method of claim 1 , wherein, prior to adding the surface-active substance in step a)ii), the water content of the fermentation broth is adjusted to a value of 35 to 50% by weight.

6. The method of claim 1 , wherein, prior to drying, the surface-active substance is present in the fermentation broth in an amount of 0.3 to 10% by weight.

7. The method of claim 1 , wherein the L-amino acid is L-lysine, L-methionine, L-threonine, L-valine or L-tryptophan.

8. The method of claim 1 , wherein the L-amino acid is L-lysine and, after completion of the fermentation and before the start of the drying, ammonium sulphate and/or sulphuric acid is added to the fermentation broth in order to establish a sulphate/L-amino acid ratio of 0.85 to 1.2.

9. The method of claim 1 , wherein the fermentation broth used in drying comprises:

a) a biomass content of 2 to 12% by weight;

b) an L-amino acid content of 12 to 48% by weight;

c) a solids content, including biomass, of 25 to 70% by weight;

e) a percentage by weight ratio of sulphate to L-amino acid of 0.8 to 1.2;

d) a surface-active substance content of 0.1 to 20% by weight.

10. The method of claim 9 , wherein the fermentation broth used in drying comprises:

a) a biomass content of 4 to 8% by weight;

b) an L-amino acid content of 12 to 48% by weight;

c) a solids content, including biomass, of 35 to 60% by weight;

d) a surface-active substance content of 0.3 to 10% by weight.

11. The method of claim 1 , wherein the feed additive comprises bacteria of the genus Corynebacterium or the genus Escherichia and/or cell debris from these bacteria.

12. The method of claim 1 , wherein said particle density is 1.40-1.55 g/cm 3 .

13. The method of claim 1 , wherein said particle density is 1.44-1.52 g/cm 3 .

14. The method of claim 1 , wherein drying step b) is by spray granulation.

15. The method of claim 1 , wherein the feed additive is a granulate with a moisture content of, at most, 3.5% by weight.

16. The method of claim 1 , wherein the amino acid content of the dried feed additive is at least 30% by weight.

17. The method of claim 1 , wherein the amino acid content of the dried feed additive is 40% to 60% by weight.

18. The method of claim 1 , wherein the particles in the feed additive are homogeneous.

19. The feed method of claim 1 , wherein the feed additive has cavities of less than 25% by volume.

20. The feed method of claim 1 , wherein the feed additive has cavities of less than 10% by volume.

Assignments (2)
CHANGE OF NAME Recorded Dec 24, 2021
From: EVONIK DEGUSSA GMBH
To: EVONIK OPERATIONS GMBH
Reel/Frame 058578/0558 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 20, 2021
From: OELMANN, ANSGAR; ALT, HANS CHRISTIAN; BLÜMKE, WILFRIED; BECKER, FRANZ ULRICH; CONRAD, CHRISTOPHER JOHN
To: EVONIK DEGUSSA GMBH
Reel/Frame 058433/0636 →
Priority Claims (1)
EP 13190055 · Oct 24, 2013 · regional
Continuity (2)
Division 15031258
Related Publication 20220104519A1 · Apr 7, 2022