IP Library Granted Patent US 11,937,823
Granted Patent B2
US 11,937,823 · App. 17/625,657 · Granted Mar 26, 2024

Gradually restricting vascular blood flow

Inventor: Michael Gabriel Tal (Tel Aviv, IL)
Assignee: VenaCore Inc.
A61B17/12036A61B17/12109A61B17/12145A61F2/848A61F2/915A61F2002/068A61F2230/005A61F2250/0039
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Quick Facts
Patent No.
US 11,937,823
App. No.
17/625,657
Granted
Mar 26, 2024
Kind
B2
Abstract

Disclosed are implant and method for gradually restricting vascular blood flow in a host blood vessel. The implant N comprising an elongated body and at least one holding member. Implant body comprising a flow restricting portion enclosing a variable minimal internal diameter. Holding member is configured for restraining implant body to maintain the variable minimal internal diameter in a first minimal internal diameter, and to physically yield voluntarily after a first predetermined average duration of being continuously subjected to internal human body conditions, thereby releasing and allowing the implant body to elastically deform voluntarily such that the variable minimal internal diameter changes to a second minimal internal diameter, smaller than the first minimal internal diameter.

Claims (20)

1. An implant for gradually restricting vascular blood flow, comprising:

an elongated implant body comprising a flow restricting portion enclosing a variable minimal internal diameter; at least one first holding member configured for restraining the implant body to maintain the variable minimal internal diameter in a first minimal internal diameter, the at least one first holding member is configured to physically yield voluntarily after a first predetermined average duration of being continuously subjected to internal human body conditions, thereby releasing and allowing the implant body to elastically deform voluntarily such that the variable minimal internal diameter changes to a second minimal internal diameter, smaller than the first minimal internal diameter; and

at least one second holding member configured for restraining the implant body to maintain the variable minimal internal diameter in the second minimal internal diameter, after the first holding member physically yields, the second holding member is configured to physically yield voluntarily following a second predetermined average duration, greater than the first average duration, of being continuously subjected to human body conditions, thereby releasing and allowing the implant body to elastically deform voluntarily such that the variable minimal internal diameter changes to a third minimal internal diameter, smaller than the second minimal internal diameter.

2. The implant according to claim 1 , wherein at least a portion of the elongated body is configured as a stent and/or a mesh, and/or is formed by way of braiding, weaving, knitting, extruding or laser cutting.

3. The implant according to claim 1 , wherein the first holding member is formed of a biodegradable material, optionally particularly configured as a biodegradable surgical suture.

4. The implant according to claim 1 , wherein the first average duration is within a range of one day to one month, optionally particularly of one week to two weeks.

5. The implant according to claim 1 , wherein the implant body includes a distal anchoring portion provided distally to the flow restricting portion and/or a proximal anchoring portion provided proximally to the flow restricting portion.

6. The implant according to claim 5 , wherein the distal anchoring portion and/or the proximal anchoring portion are self-expandable or balloon-expandable for securing the implant body to an intralumenal surface of a host blood vessel.

7. The implant according to claim 5 , wherein the distal anchoring portion and/or the proximal anchoring portion are expandable to a maximally allowed outer diameter being equal to or greater than an average lumen diameter of a superior vena cava in an adult human subject.

8. The implant according to claim 5 , wherein the distal anchoring portion and/or the proximal anchoring portion are configured with a stent structure and includes a plurality of stent rings, each ring formed of a plurality of stent struts.

9. The implant according to claim 5 , wherein the flow restricting portion includes or is configured as one or more spaced-apart struts or cells collectively enclosing therebetween a constricted passage of the variable minimal internal diameter.

10. The implant according to claim 9 , wherein the constricted passage is covered and/or impregnated with a flexible material configured to resist and/or block blood flow therethrough.

11. An implant for gradually restricting vascular blood flow, comprising:

an elongated implant body comprising a flow restricting portion enclosing a variable minimal internal diameter; and

at least one first holding member configured for restraining the implant body to maintain the variable minimal internal diameter in a first minimal internal diameter, the at least one first holding member is configured to physically yield voluntarily after a first predetermined average duration of being continuously subjected to internal human body conditions, thereby releasing and allowing the implant body to elastically deform voluntarily such that the variable minimal internal diameter changes to a second minimal internal diameter, smaller than the first minimal internal diameter;

wherein the implant body includes a distal anchoring portion provided distally to the flow restricting portion and/or a proximal anchoring portion provided proximally to the flow restricting portion, and wherein the flow restricting portion is connected to the distal anchoring portion and/or the proximal retention portion via one or more elastic connecting members.

12. The implant according to claim 11 , wherein each connecting member has elastically stressed portions when the variable minimal internal diameter is set in the first minimal internal diameter, the elastically stressed portions being configured to shift into a less elastically stressed state when the variable minimal internal diameter is set in the second minimal internal diameter.

13. The implant according to claim 11 , wherein each connecting member is pulled towards the distal anchoring portion and/or the proximal anchoring portion by one or more of the at least one first holding member.

14. The implant according to claim 11 , wherein each connecting member is fastened to the distal anchoring portion and/or the proximal anchoring portion by one or more of the at least one first holding member.

15. The implant according to claim 11 , wherein each connecting member is forced into a straightened form by one or more of the at least one first holding member.

Assignments (2)
CHANGE OF NAME Recorded May 26, 2026
From: VENACORE, INC.
To: TOTAL MEDICAL INC.
Reel/Frame 074757/0180 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 19, 2022
From: TAL, MICHAEL GABRIEL
To: VENACORE INC.
Reel/Frame 059635/0451 →
Continuity (3)
Provisional Application 62968406 · Jan 31, 2020
Provisional Application 62872085 · Jul 9, 2019
Related Publication 20220296247A1 · Sep 22, 2022