Treating upper airway nerve tissue
Systems and methods for treating a patient's mucus hypersecretion condition are disclosed herein. Certain implementations may involve a method for reducing mucus secretion in an upper airway of a patient to treat at least one of post nasal drip or chronic cough. The method may include advancing a treatment delivery portion of an energy-based treatment device into a nostril of the patient. The treatment delivery portion may contact mucosal tissue of the upper airway without piercing the mucosal tissue. The treatment delivery portion may deliver treatment to at least one tissue selected from the group of the mucosal tissue and another tissue underlying the mucosal tissue to modify a property of the at least one tissue and thus treat at least one of post nasal drip or chronic cough in the patient.
1. A method for treating a nasal cavity of a patient by deactivating nerve tissue without forming an incision or implanting an implant, the method comprising:
advancing a treatment element of a treatment device into a nostril of the patient;
expanding multiple pre-shaped segments of the treatment element to cause them to contact mucosa lining the nasal cavity; and
delivering radiofrequency energy through the mucosa with at least a first pair of bipolar radiofrequency electrodes on at least two of the pre-shaped segments, while leaving at least a second pair of bipolar radiofrequency electrodes on the pre-shaped segments in an inactive state,
wherein delivering the radiofrequency energy with at least the first pair of bipolar radiofrequency electrodes deactivates the nerve tissue underlying the mucosa.
2. The method of claim 1 , wherein delivering the radiofrequency energy ablates the nerve tissue.
3. The method of claim 1 , wherein expanding the pre-shaped segments comprises by exposing them to a change of temperature past a transition temperature.
4. The method of claim 1 , further comprising using a control system coupled with the treatment device to select at least the first pair of bipolar radiofrequency electrodes for delivering the radiofrequency energy and to select at least the second pair of bipolar radiofrequency electrodes for maintaining in the inactive state.
5. The method of claim 4 , further comprising measuring impedance with an impedance sensor in the control system.
6. The method of claim 5 , wherein measuring the impedance comprises:
activating at least the first pair of bipolar radiofrequency electrodes and the second pair of bipolar radiofrequency electrodes;
measuring a first impedance in the first pair of bipolar radiofrequency electrodes; and
measuring a second impedance in the second pair of bipolar radiofrequency electrodes.
7. The method of claim 6 , further comprising:
determining, with the controller, that the second impedance is outside a desired range.
8. The method of claim 1 , further comprising sensing a temperature of the mucosa with at least one thermocouple attached to at least one of the pre-shaped segments.
9. The method of claim 1 , further comprising determining that the patient has a nasal mucus hypersecretion condition, wherein deactivating the nerve tissue ameliorates at least one symptom of the nasal mucus hypersecretion condition.
10. A system for treating a nasal cavity of a patient without forming an incision or implanting an implant, the system comprising:
a treatment device, comprising:
a handle;
a shaft extending from the handle; and
a treatment element coupled with a distal end of the shaft and sized to allow it to pass into the nasal cavity of the patient, wherein the treatment element comprises:
multiple pre-shaped expandable segments; and
multiple pairs of bipolar radiofrequency electrodes disposed on the multiple pre-shaped expandable segments;
a control system coupled with the treatment device, comprising:
a generator for providing radiofrequency energy to the multiple pairs of bipolar radiofrequency electrodes; and
an impedance sensor for sensing impedance between the multiple pairs of bipolar radiofrequency electrodes.
11. The system of claim 10 , wherein the multiple pre-shaped expandable segments are made of a shape-memory material selected from the group consisting of nickel-cobalt, nickel-titanium, shape memory polymers, and biodegradable polymers.