IP Library › Granted Patent US 11,559,672
Granted Patent B2
US 11,559,672 · App. 17/662,413 · Granted Jan 24, 2023

Left atrial appendage stasis reduction

Inventors: Glen Rabito (Irvine, CA); Joseph Passman (Irvine, CA); Robert C. Taft (Irvine, CA); Stanton J. Rowe (Irvine, CA); Robert S. Schwartz (Irvine, CA); Alexander Siegel (Irvine, CA)
Assignee: NXT Biomedical, LLC
A61M27/002A61B17/0057A61F2/2487A61F2/82A61M60/161A61M60/165A61M60/216A61M60/289A61M60/861A61B2017/00632A61M2205/75A61M2206/20A61M2210/125
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Quick Facts
Patent No.
US 11,559,672
App. No.
17/662,413
Granted
Jan 24, 2023
Kind
B2
Abstract

Methods and devices that prevent stasis in the LAA by either increasing the flow through the LAA or by closing off or sealing the LAA. Increasing the flow is accomplished through shunts, flow diverters, agitators, or by increasing the size of the ostium. Closing off the LAA is accomplished using seals or by cinching the LAA.

Claims (26)

1. A method of increasing flow through a left atrial appendage comprising: creating a passageway traversing through a wall of a pulmonary vein and a wall of the left atrial appendage; and resistively diverting flow from the pulmonary vein directly into the left atrial appendage through the passageway such that a majority of the flow passes into the left atrial appendage and washes out the left atrial appendage.

2. The method of claim 1 , wherein creating the passageway traversing through the wall of the pulmonary vein and the wall of the left atrial appendage comprises placing a flow diverter in the pulmonary vein, upstream of a left lateral ridge, that leads directly into the left atrial appendage.

3. The method of claim 2 , further comprising causing all blood from the pulmonary vein to flow through the flow diverter.

4. The method of claim 3 , wherein causing all blood to flow through the flow diverter comprises implanting a flow resistor in the pulmonary vein such that pressure builds in the pulmonary vein, which is relieved by blood flowing through the flow diverter directly into the left atrial appendage.

5. The method of claim 2 , further comprising implanting a flow resistor downstream of the flow diverter near the left lateral ridge.

6. The method of claim 5 , wherein the flow diverter is comprised of a shunt and wherein the flow resistor is comprised of a stent.

7. The method of claim 5 , wherein the flow resistor is comprised of a flow inhibitor.

8. The method of claim 1 , further comprising directing the flow towards a sidewall of the left atrial appendage such that a vortex is created within the left atrial appendage.

9. A method of increasing a blood flow through a left atrial appendage, comprising:

connecting an inlet of a flow diverter to a pulmonary vein such that the inlet of the flow diverter extends through a wall of the pulmonary vein;

connecting an outlet of the flow diverter to the left atrial appendage such that the outlet of the flow diverter extends through a wall of the left atrial appendage, wherein the flow diverter is placed directly between the pulmonary vein and the left atrial appendage; and

resistively diverting a majority of the blood flow through the flow diverter into the left atrial appendage to wash out the left atrial appendage.

10. The method of claim 9 , wherein the flow diverter is comprised of a shunt.

11. The method of claim 9 , further comprising filtering blood flowing through the flow diverter.

12. The method of claim 9 , further comprising causing all of the blood to flow through the inlet of the flow diverter.

13. The method of claim 9 , wherein causing blood to flow through the inlet of the flow diverter comprises placing a flow resistor in the pulmonary vein downstream of the flow diverter, wherein the flow resistor is separate from the flow diverter.

14. The method of claim 13 , wherein the flow resistor is placed near a left lateral ridge.

15. The method of claim 13 , wherein the flow resistor is comprised of a stent.

16. The method of claim 13 , wherein the flow resistor is comprised of a braided flow inhibitor.

17. The method of claim 9 , further comprising orienting the outlet of the flow diverter towards a sidewall of the left atrial appendage such that the blood flow creates a vortex within the left atrial appendage.

18. A method of increasing a blood flow through a left atrial appendage, comprising:

placing a flow diverter directly between a pulmonary vein and the left atrial appendage;

placing a flow resistor in the pulmonary vein downstream of the flow diverter, wherein the flow resistor is separate from the flow diverter; and,

allowing blood to flow through the flow diverter and the flow resistor directly into the left atrial appendage.

19. The method of claim 18 , wherein the flow resistor is placed near a left lateral ridge.

20. The method of claim 18 , further comprising directing the blood flow towards a sidewall of the left atrial appendage such that a vortex is created within the left atrial appendage.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 29, 2026
From: NXT BIOMEDICAL, LLC
To: NIDUS BIOMEDICAL, LLC
Reel/Frame 073623/0168 →
Continuity (7)
Continuation 17424840
Provisional Application 62906001 · Sep 25, 2019
Provisional Application 62881239 · Jul 31, 2019
Provisional Application 62845528 · May 9, 2019
Provisional Application 62835434 · Apr 17, 2019
Provisional Application 62803337 · Feb 8, 2019
Related Publication 20220331566A1 · Oct 20, 2022
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