IP Library Granted Patent US 11,765,340
Granted Patent B2
US 11,765,340 · App. 17/689,339 · Granted Sep 19, 2023

Goggle imaging systems and methods

Inventors: Samuel Achilefu (St. Louis, MO); Yang Liu (Akron, OH); Viktor Gruev (St. Louis, MO); Joseph P. Culver (Webster Groves, MO); Walter Akers (Columbia, IL); Adam Bauer (Webster Groves, MO)
Assignee: WASHINGTON UNIVERSITY
H04N13/344A61B34/25A61B90/30A61B90/36A61B90/361A61K49/0032A61K49/0034A61K49/0056C07K7/06G02B27/017H04N25/76A61B1/0005A61B1/0692A61B2090/364
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Quick Facts
Patent No.
US 11,765,340
App. No.
17/689,339
Granted
Sep 19, 2023
Kind
B2
Abstract

A goggle system is provided. The goggle system includes a computing device, a goggle device configured to be worn by a user and including a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode, at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode, and a communications module configured to transmit acquired image data from the goggle device to the computing device.

Claims (39)

1. A goggle system comprising:

a computing device; and

a goggle device configured to be worn by a user and comprising:

a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode;

at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode; and

a communications module configured to transmit acquired image data from said goggle device to said computing device.

2. A goggle system according to claim 1 , wherein said goggle device further comprises a white light source.

3. A goggle system according to claim 1 , wherein said goggle device further comprises a fluorescence excitation light source.

4. A goggle system according to claim 1 , further comprising a fluorescence excitation light source detached from said goggle device.

5. A goggle system according to claim 1 , wherein said detector is configured to acquire visible light image data in the first image mode and fluorescence image data in the second image mode.

6. A goggle system accordingly to claim 1 , wherein said detector comprises a detector array comprising:

a plurality of first image mode detector elements; and

a plurality of second image mode detector elements, wherein said first and second image mode detector elements are arranged in a checkerboard pattern.

7. A goggle system according to claim 6 , wherein at least one of said plurality of first image mode detector elements and said plurality of second image mode detector elements comprises a plurality of alternating layers containing p-n junctions.

8. A goggle system according to claim 1 , wherein said goggle device further comprises a switch configured to switch between different imaging modes displayed on said at least one eye assembly.

9. A goggle system according to claim 1 , wherein said at least one eye assembly includes a pixel array comprising:

a plurality of first image mode pixels; and

a plurality of second image mode pixels, wherein said first and second image mode pixels are arranged in a checkerboard pattern.

10. A goggle device configured to be worn by a user and comprising:

a detector configured to simultaneously acquire image data of a subject in a first image mode and a second image mode; and

at least one eye assembly configured to display at least one of an image in the first image mode, an image in the second image mode, and a hybrid image including pixels of image data from the first image mode and pixels of image data from the second image mode.

11. A goggle device according to claim 10 , further comprising a white light source.

12. A goggle device according to claim 10 , further comprising a fluorescence excitation light source.

13. A goggle device according to claim 10 , wherein said detector is configured to acquire visible light image data in the first image mode and fluorescence image data in the second image mode.

14. A goggle device according to claim 10 , wherein said detector comprises a detector array comprising:

a plurality of first image mode detector elements; and

a plurality of second image mode detector elements, wherein said first and second image mode detector elements are arranged in a checkerboard pattern.

15. A goggle device according to claim 14 , wherein at least one of said plurality of first image mode detector elements and said plurality of second image mode detector elements comprises a plurality of alternating layers containing p-n junctions.

16. A goggle device according to claim 10 , wherein said goggle device further comprises a switch configured to switch between different imaging modes displayed on said at least one eye assembly.

17. A goggle device according to claim 10 , wherein said at east one eye assembly includes a pixel array comprising:

a plurality of first image mode pixels; and

a plurality of second image mode pixels, wherein said first and second image mode pixels are arranged in a checkerboard pattern.

18. A goggle device according to claim 10 , wherein said at east one eye assembly comprises:

a left eye assembly configured to display an image to a left eye of the user; and a right eye assembly configured to display an image to a right eye of the user.

19. A method for fluorescence imaging, said method comprising:

administering a fluorescent molecular probe to a subject;

observing the subject using a goggle device configured for at least one of visible light and near infrared light imaging; and

identifying; using the goggle device, at least one tumor in the subject based on a binding of the fluorescent molecular probe to tissue.

20. A method in accordance with claim 19 , wherein administering a fluorescent molecular probe comprises administering a fluorescent molecular probe via at least one of intravenous, transdermal, oral, tracheal, intraperitoneal, and transarterial delivery.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 10, 2022
From: ACHILEFU, SAMUEL; CULVER, JOSEPH; AKERS, WALTER; BAUER, ADAM; GRUEV, VIKTOR; LIU, YANG
To: WASHINGTON UNIVERSITY
Reel/Frame 059224/0865 →
Continuity (5)
Continuation 17122848 · Dec 15, 2020
Continuation 16169071 · Oct 24, 2018
Continuation 14374002
Provisional Application 61589623 · Jan 23, 2012
Related Publication 20220201274A1 · Jun 23, 2022