Electrode Assemblies for Measuring Impedance
An electrode assembly includes an electrically-conductive wire configured for insertion into a blood vessel of a subject, an electrode surrounding the wire, and a discontinuous electrically-insulating cover disposed between the wire and the electrode such that the wire lies radially opposite the electrode at a break in the discontinuous electrically-insulating cover. Other embodiments are also described.
1 . An electrode assembly, comprising:
an electrically-conductive wire, configured for insertion into a blood vessel of a subject;
an electrode surrounding the wire; and
a discontinuous electrically-insulating cover disposed between the wire and the electrode such that the wire lies radially opposite the electrode at a break in the discontinuous electrically-insulating cover.
2 . The electrode assembly according to claim 1 , wherein the electrode is shaped to define a helix.
3 . The electrode assembly according to claim 1 , wherein the electrode comprises a mesh.
4 . The electrode assembly according to claim 1 , wherein the electrode is coupled to the discontinuous electrically-insulating cover.
5 . The electrode assembly according to claim 1 , wherein a length of the break is less than 5 mm.
6 . The electrode assembly according to claim 1 , further comprising a reinforcing tube disposed around the discontinuous electrically-insulating cover.
7 . The electrode assembly according to claim 6 , wherein the reinforcing tube is proximal to the break.
8 . The electrode assembly according to claim 6 , wherein the reinforcing tube is distal to the break.
9 . The electrode assembly according to claim 6 , further comprising another electrode coupled to the reinforcing tube.
10 . The electrode assembly according to claim 1 , wherein the break includes a perforation in the discontinuous electrically-insulating cover.
11 . The electrode assembly according to claim 10 , wherein a surface area of the perforation is less than 0.8 mm 2 .
12 . Apparatus, comprising:
the electrode assembly according to claim 1 ; and
a treatment device, comprising:
a treatment element configured to treat an occlusion in the blood vessel; and
an electrically-insulating tube configured to facilitate delivery of the treatment element to the occlusion by advancing over the electrode assembly.
13 . The apparatus according to claim 12 ,
wherein the occlusion includes a thrombus,
wherein a distal portion of the electrically-insulating tube is shaped to define one or more apertures, and
wherein the treatment element comprises a treatment electrode surrounding the distal portion of the electrically-insulating tube and configured to attract the thrombus when a signal is applied between the treatment electrode and any electrically-conductive element disposed within the electrically-insulating tube, by virtue of an electrical current flowing through the apertures.
14 . The apparatus according to claim 13 ,
wherein the electrically-insulating tube is shaped to define a first lumen and a second lumen,
wherein the treatment element further comprises a return electrode,
wherein the signal is applied between the treatment electrode and the return electrode while the return electrode is disposed within the first lumen, and
wherein the electrically-insulating tube is configured to advance over the electrode assembly while the electrode assembly is disposed within the second lumen.
15 . The apparatus according to claim 14 , wherein the electrically-insulating tube is shaped to define a lateral window opening into the second lumen and disposed between a proximal end of the treatment electrode and a distal end of the treatment electrode.
16 . A method, comprising:
inserting, into a blood vessel of a subject, an electrode assembly including:
a wire,
an electrode surrounding around the wire, and
a discontinuous electrically-insulating cover disposed between the wire and the electrode such that the wire lies radially opposite the electrode at a break in the discontinuous electrically-insulating cover;
subsequently to inserting the electrode assembly, moving the electrode assembly through the blood vessel while monitoring a signal between the electrode and the wire, which results from ions flowing between the wire and the electrode via the break; and
treating an occlusion in the blood vessel responsively to the signal.
17 . The method according to claim 16 , wherein treating the occlusion comprises:
responsively to the signal, positioning a treatment device, which includes an electrically-insulating tube, by advancing the electrically-insulating tube over the electrode assembly; and
using the treatment device, treating the occlusion.
18 . The method according to claim 17 ,
wherein the occlusion includes a thrombus,
wherein the signal is a first signal,
wherein a distal portion of the electrically-insulating tube is shaped to define one or more apertures,
wherein the treatment device further includes a treatment electrode surrounding the distal portion of the electrically-insulating tube such that the apertures are disposed between a proximal end of the treatment electrode and a distal end of the treatment electrode, and
wherein treating the thrombus comprises attracting the thrombus to the treatment electrode by applying a second signal between the treatment electrode and any electrically-conductive element disposed within the electrically-insulating tube, by virtue of an electric current flowing through the apertures.
19 . The method according to claim 18 , wherein treating the thrombus further comprises:
subsequently to a start of the second signal, withdrawing the electrically-insulating tube and the electrode assembly from the blood vessel while the break in the discontinuous electrically-insulating cover is aligned with at least one of the apertures; and
while withdrawing the electrically-insulating tube and the electrode assembly, monitoring the first signal.
20 . The method according to claim 18 , wherein the electrically-conductive element is selected from the group of elements consisting of: the wire, the electrode, and another electrically-conductive element disposed over the wire.
21 . The method according to claim 18 ,
wherein the electrically-insulating tube is shaped to define a first lumen and a second lumen,
wherein the apertures open into the first lumen,
wherein the electrically-conductive element includes a return electrode disposed within the first lumen, and
wherein advancing the electrically-insulating tube over the electrode assembly comprises advancing the electrically-insulating tube over the electrode assembly while the electrode assembly is disposed within the second lumen.
22 . The method according to claim 21 , wherein the electrically-insulating tube is shaped to define a lateral window opening into the second lumen and disposed between a proximal end of the treatment electrode and a distal end of the treatment electrode, and wherein treating the thrombus further comprises:
subsequently to a start of the second signal, withdrawing the electrically-insulating tube and the electrode assembly from the blood vessel while the break in the discontinuous electrically-insulating cover is aligned with the lateral window; and
while withdrawing the electrically-insulating tube and the electrode assembly, monitoring the first signal.
23 . The method according to claim 16 ,
wherein the occlusion includes a thrombus,
wherein the signal is a first signal, and
wherein treating the thrombus comprises:
positioning the electrode assembly responsively to the first signal; and
attracting the thrombus to the electrode by applying a second signal between the electrode and the wire.
24 . The method according to claim 16 , further comprising generating the signal by applying a voltage or current between the electrode and the wire.
25 . The method according to claim 16 ,
wherein the electrode assembly further includes a pair of other electrodes, and
wherein the method further comprises generating the signal by applying a voltage or current between the pair of other electrodes.