IP Library Granted Patent US 12,076,587
Granted Patent B2
US 12,076,587 · App. 17/707,738 · Granted Sep 3, 2024

Dose smearing effect modeling for radiation treatment plan

Inventors: Pierre Lansonneur (Helsinki, FI); Perttu Niemela (Espoo, FI); Michiko Rossi (Espoo, FI); Matti Sakari Ropo (Helsinki, FI); Viljo Petaja (Espoo, FI)
Assignee: Siemens Healthineers International AG
A61N5/1031A61N2005/1034A61N2005/1087
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Quick Facts
Patent No.
US 12,076,587
App. No.
17/707,738
Granted
Sep 3, 2024
Kind
B2
Abstract

A computer implemented method of developing a radiation treatment plan comprising spot scanning of a treatment target comprising accessing information associated with a patient and information pertaining to a radiation delivery machine. The method further comprises determining an area associated with the treatment target, wherein the area comprises a plurality of spots and computing a weighting for each spot of the plurality of spots, wherein the weighting is associated with a number of protons delivered at a respective spot. Further, the method comprises computing timing related parameters based on information retrieved from the radiation delivery machine and determining a transition dose delivered by the radiation delivery machine during the transition from one spot to another spot when irradiating the treatment target.

Claims (51)

1. A computer implemented method of developing a radiation treatment plan comprising spot scanning of a treatment target, said method comprising:

accessing information associated with a patient and information pertaining to a radiation delivery machine;

determining an area associated with the treatment target, wherein the area comprises a plurality of spots;

computing a weighting for each spot of the plurality of spots, wherein the weighting is associated with a number of protons delivered at a respective spot;

computing timing related parameters based on information retrieved from the radiation delivery machine; and

determining a transition dose delivered by the radiation delivery machine during a transition from one spot to another spot when irradiating the treatment target under the radiation treatment plan.

2. The method of claim 1 , further comprising:

determining a spot dose for each spot of the plurality of spots; and

computing a total dose distribution for the radiation treatment plan by accumulating a spot dose determined for each spot of the plurality of spots and a transition dose determined for each transition from one spot to another during the irradiating under the treatment plan.

3. The method of claim 1 , wherein the determining the transition dose comprises determining a transmission dose matrix by modeling a line associated with the transition from the one spot to the another spot as a series of finite spots.

4. The method of claim 1 , wherein the determining the transition dose comprises determining a transmission dose matrix by modeling a line associated with the transition from the one spot to the another spot as a summation of a series of infinite spots.

5. The method of claim 1 , wherein the determining the transition dose comprises:

modeling a line associated with the transition from the one spot to the another spot as a summation of a series of infinite spots; and

performing a statistical computation to determine a transition dose matrix associated with the transition dose.

6. The method of claim 5 , wherein the statistical computation is a Monte Carlo calculation.

7. The method of claim 1 , further comprising:

determining a spot dose for each spot of the plurality of spots; and

computing a total dose distribution for the radiation treatment plan by accumulating a spot dose determined for each spot of the plurality of spots and a transition dose determined for each transition from one spot to another during the irradiating, wherein the total dose distribution depends on a pattern followed by the radiation delivery machine during the irradiating.

8. A computer system comprising a processor coupled to a bus and memory coupled to said bus, wherein said memory is programmed with instructions that when executed cause said computer system to implement a method of developing a radiation treatment plan comprising spot scanning of a treatment target, wherein said method comprises:

accessing information associated with a patient and information pertaining to a radiation delivery machine;

determining an area associated with the treatment target, wherein the area comprises a plurality of spots;

computing a weighting for each spot of the plurality of spots, wherein the weighting is associated with a number of protons delivered at a respective spot;

computing timing related parameters based on information retrieved from the radiation delivery machine;

computing a dose delivered at each spot of the plurality of spots; and

determining a plurality of transition doses delivered by the radiation delivery machine, wherein the plurality of transition doses comprise a radiation delivered during each transition from one spot to another spot when irradiating the treatment target under the radiation treatment plan.

9. The computer system of claim 8 , wherein the method further comprises:

determining a total dose distribution by summing up the plurality of transition doses with the dose delivered at each respective spot of the plurality of spots.

10. The computer system of claim 8 , wherein the determining the plurality of transition doses comprises determining a transmission dose matrix for each transition by modeling a line associated with a respective transition as a series of finite spots.

11. The computer system of claim 8 , wherein the determining the plurality of transition doses comprises determining a transmission dose matrix for each transition by modeling a line associated with a respective transition as a summation of a series of infinite spots.

12. The computer system of claim 8 , wherein the determining the plurality of transition doses comprises:

modeling a line associated with each transition as a summation of a series of infinite spots; and

performing a statistical computation to determine a transition dose matrix associated with each transition.

13. The computer system of claim 8 , wherein the statistical computation is a Monte Carlo calculation.

14. A non-transitory computer-readable storage medium having computer-executable instructions for causing a computer system to perform a method of developing a radiation treatment plan comprising spot scanning of a treatment target, the method comprising:

accessing information associated with a patient and information pertaining to a radiation delivery machine;

determining an area associated with the treatment target, wherein the area comprises a plurality of spots;

computing a weighting for each spot of the plurality of spots, wherein the weighting is associated with a number of protons delivered at a respective spot;

computing timing related parameters based on information retrieved from the radiation delivery machine; and

determining a transition dose delivered by the radiation delivery machine during a transition between spots when irradiating the treatment target under the treatment plan.

15. The non-transitory computer-readable storage medium of claim 14 , wherein the method further comprises:

determining a spot dose for each spot of the plurality of spots; and

computing a total dose distribution for the radiation treatment plan by accumulating a spot dose determined for each spot of the plurality of spots and a transition dose determined for each transition between spots during the irradiating.

16. The non-transitory computer-readable storage medium of claim 14 , wherein the determining the transition dose comprises determining a transmission dose matrix by modeling a line associated with the transition between spots as a series of finite spots.

17. The non-transitory computer-readable storage medium of claim 14 , wherein the determining the transition dose comprises determining a transmission dose matrix by modeling a line associated with the transition between spots as a summation of a series of infinite spots.

18. The non-transitory computer-readable storage medium of claim 14 , wherein the determining the transition dose comprises:

modeling a line associated with the transition as a summation of a series of infinite spots; and

performing a statistical computation to determine a transition dose matrix associated with the transition dose.

19. The non-transitory computer-readable storage medium of claim 18 , wherein the statistical computation is a Monte Carlo calculation.

20. The non-transitory computer-readable storage medium of claim 14 , wherein the method further comprises:

determining a spot dose for each spot of the plurality of spots; and

computing a total dose distribution for the radiation treatment plan by accumulating a spot dose determined for each spot of the plurality of spots and a transition dose determined for each transition between spots during the irradiating, wherein the total dose distribution depends on a pattern followed by the radiation delivery machine during the irradiating.

Assignments (2)
MERGER AND CHANGE OF NAME Recorded Mar 1, 2023
From: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG; VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 062901/0952 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 29, 2022
From: LANSONNEUR, PIERRE; NIEMELA, PERTTU; ROSSI, MICHIKO; ROPO, MATTI SAKARI; PETAJA, VILJO
To: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
Reel/Frame 059430/0866 →
Continuity (1)
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