Granted Patent
B2
US 12,285,330 · App. 17/733,914 · Granted Apr 29, 2025
Prosthesis for atraumatically grasping intralumenal tissue and methods of delivery
Inventors:
J. Brent Ratz (Winchester, MA); Arshad Quadri (West Hartford, CT); Luca Pesce (Huntington Beach, CA)
Assignee:
Edwards Lifesciences CardiAQ LLC
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Loading inventors, assignments & file history…
Abstract
A prosthesis can comprise an expandable frame, a plurality of distal anchors and a plurality of proximal anchors. The anchors can extend outwardly from the frame. The frame can be configured to radially expand and contract for deployment within a body cavity. The frame and anchors can have one of many different shapes and configurations. For example, when the frame is in an expanded configuration, the frame can have a larger cross-sectional dimension in a middle portion of the frame and a smaller cross-sectional dimension in a proximal portion and a distal portion of the frame, wherein the middle portion is between the proximal and distal portions. As another example, the anchors can have looped ends, the entire anchor may loop out from the frame.
Claims (18)
1. A self-expanding replacement valve prosthesis comprising:
an expandable frame comprising a first end and a second end and having a longitudinal axis extending between the first end and the second end, the expandable frame configured to radially expand and contract for deployment within a native heart valve, wherein, when the expandable frame is in an expanded configuration, the expandable frame, excluding anchors, has a bulbous shape such that a cross-sectional dimension of the expandable frame increases from a smaller cross-sectional dimension at the first end to a larger cross-sectional dimension in a middle portion of the expandable frame and then decreases from the middle portion to a smaller cross-sectional dimension at the second end of the expandable frame, the middle portion being between the first end and the second end,
wherein the expandable frame comprises a plurality of cells formed by interconnected struts;
a valve body attached to the expandable frame, the valve body comprising a plurality of prosthetic heart valve leaflets;
a plurality of generally longitudinal struts extending from the first end, each of the plurality of generally longitudinal struts comprising a mushroom-shaped tab;
a plurality of anchors extending from a base attached to the expandable frame generally distally beyond the base and in a direction opposite the first end and then radially outwardly before extending generally towards the first end of the expandable frame, wherein the base of each of the plurality of anchors is at a location where corners of two adjacent cells of a distal-most row of the plurality of cells of the expandable frame are connected, such that each of the plurality of anchors extends from a trough of a V-shaped member of the expandable frame,
wherein each of the plurality of anchors is connected to the expandable frame at the base with a single strut which splits into two struts which connect at an end of the struts to form an atraumatic looped end and wherein the plurality of anchors have a length sufficient to extend between and provide tension on chordae tendineae positioned adjacent the native heart valve;
a first fabric portion covering at least a portion of the second end of the expandable frame; and
a plurality of second fabric portions each covering at least a portion of each of the plurality of anchors.
2. The prosthesis of claim 1 , wherein the plurality of cells are diamond-shaped cells.
3. The prosthesis of claim 2 , wherein adjacent looped ends of the plurality of anchors are spaced apart by at least one cell.
4. The prosthesis of claim 1 , wherein, when the self-expanding replacement valve prosthesis is expanded within the native heart valve, the middle portion is sized and adapted to engage a native valve annulus.
5. The prosthesis of claim 1 , wherein the atraumatic end of each of the plurality of anchors is covered by the plurality of second fabric portions.
6. The prosthesis of claim 1 , wherein the two struts form a generally triangular loop.
7. The prosthesis of claim 1 , wherein the prosthesis is a replacement mitral valve prosthesis.
8. The prosthesis of claim 1 , wherein the prosthesis is a replacement tricuspid valve prosthesis.
9. The prosthesis of claim 1 , wherein the prosthesis is a replacement atrioventricular valve prosthesis.
10. The prosthesis of claim 1 , wherein the expandable frame further comprises a plurality of second anchors extending from the expandable frame and extending radially outwardly before extending generally towards the second end of the expandable frame, wherein, when the expandable frame is in an expanded condition, opposing anchors and second anchors are drawn closer together so as to grasp tissue on opposite sides of the native heart valve, and wherein the plurality of anchors extend radially outward further than the plurality of second anchors.
Assignments (3)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Mar 8, 2024
From: RATZ, J. BRENT; QUADRI, ARSHAD; PESCE, LUCA
To: CARDIAQ VALVE TECHNOLOGIES, INC.
Reel/Frame 066706/0805 →
MERGER AND CHANGE OF NAME
Recorded Mar 8, 2024
From: IMPALA, INC.; CARDIAQ VALVE TECHNOLOGIES, INC.; CARDIAQ VALVE TECHNOLOGIES, INC.
To: EDWARDS LIFESCIENCES CARDIAQ, INC.
Reel/Frame 066706/0874 →
CERTIFICATE OF CONVERSION
Recorded Mar 8, 2024
From: EDWARDS LIFESCIENCES CARDIAQ, INC.
To: EDWARDS LIFESCIENCES CARDIAQ LLC
Reel/Frame 066766/0221 →
Continuity (5)
Provisional Application
61782707
· Mar 14, 2013
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