Synchronized aspiration system with catheter sensors for removal of acute blockages from blood vessels
An aspiration catheter for assisting in the retrieval of a clot from a vessel of a patient including at least one electrode pair and a first pressure sensor positioned within an inner lumen of the aspiration catheter and a second and third pressure sensor positioned on an exterior surface of the aspiration catheter. The electrode pair and pressure sensors are in electrical communication with a control console. The control console is configured to modulate an aspiration vacuum pressure waveform pattern applied through the aspiration catheter based on electrical and pressure inputs from the one or more sensors, and optionally based on a blood pressure waveform pattern of the patient.
1 . An aspiration catheter for assisting in retrieval of a clot from a vessel of a patient, the aspiration catheter comprising:
at least one electrode pair positioned on a first side of a wall that defines an inner lumen of the aspiration catheter, the inner lumen extending proximal along a longitudinal axis between a distal tip and a proximal hub;
a first pressure sensor positioned at a distal portion proximal the distal tip and within the inner lumen of the aspiration catheter;
a second pressure sensor positioned at a distal portion proximal the distal tip on an opposed side of the wall that defines an exterior surface of the aspiration catheter;
a third pressure sensor positioned at a proximal portion of the aspiration catheter on the exterior surface of the aspiration catheter; and
a seal located on an exterior surface of the aspiration catheter, the seal being configured to seal against the lumen of an outer catheter such that an aspiration applied through the outer catheter is transferred to the aspiration catheter.
2 . The aspiration catheter of claim 1 , wherein:
the at least one electrode pair is configured to transmit an electrical input to a control console, wherein the electrical input comprises a change in conductivity in a fluid flowing inside the inner lumen of the aspiration catheter.
3 . The aspiration catheter of claim 2 , wherein:
when the distal tip of the aspiration catheter is near the clot, the at least one electrode pair is configured to detect the clot within the fluid flowing inside the inner lumen of the aspiration catheter.
4 . The aspiration catheter of claim 1 , wherein:
when the distal tip of the aspiration catheter is engaged with the clot, the at least one electrode pair is configured to monitor the clot as the aspiration catheter is moved about the vessel.
5 . The aspiration catheter of claim 1 , wherein:
the first pressure sensor is configured to transmit a first pressure input to a control console;
the second pressure sensor is configured to transmit a second pressure input to the control console; and
the third pressure sensor is configured to transmit a third pressure input to the control console, wherein the first, second, and third pressure inputs are different.
6 . The aspiration catheter of claim 5 , wherein:
when the distal tip of the aspiration catheter is near the clot, the first pressure input and the second pressure input together generate a pressure measurement of an antegrade flow rate around the aspiration catheter in the vessel.
7 . The aspiration catheter of claim 5 , wherein:
the control console is further configured to modulate an aspiration by applying an oscillating vacuum waveform based on pressure input from one or more pressure sensors.
8 . The aspiration catheter of claim 5 , wherein:
the control console is further configured to modulate an aspiration to a waveform of a blood pressure of a patient by applying an oscillating vacuum waveform in phase with a blood pressure waveform of the patient.
9 . The aspiration catheter of claim 5 , wherein:
the control console is further configured to modulate an aspiration to a waveform of a blood pressure of a patient by applying an oscillating vacuum waveform out of phase with a blood pressure waveform of the patient.